Akraler papulöser Lichen myxoedematosus

Abstract

In 1986 Rongioletti introduced the term acral persistent papular mucinosis for persistent papules on the dorsum of the hands and distal forearms. Skin specimens reveal mucin deposits which resemble those in lichen myxedematosus (LM). Laboratory results are usually unremarkable. Our 54-year-old female patient showed a 2 1/2 year history of skin lesions in the typical acral distribution pattern. This entity appears to be an acral papular subtype of LM. In the classification of LM, acral papular lichen myxedematosus should replace the discrete papular form. This latter form has been well known for many years, but is not sufficiently definable and is of secondary clinical importance.

Acral persistent papular mucinosis: a case report and literature review

“…In most cases the lesions slowly increase in number but there are no systemic associations [3]. To our knowledge, thirty‐two cases including two from China have been reported earlier [1, 3–26] which strictly agree with the defined diagnostic criteria of APPM [3]. Besides these 32, another six cases reported in the previous century had similar lesions but did not strictly fit the criteria [3].…”

“…Only three were under 20 years of age at the onset of their lesions [14, 15], and only three had pruritic lesions [8, 13, 26]. Among the prior 27 cases which were fully described, four had past history of malignant tumors [7, 16, 17, 22] and one was found with a basal cell epithelioma at presentation [26]. Our case had history of benign thyroid tumor.…”