Airway Hyperresponsiveness in Wood Smoke Chronic Obstructive Pulmonary Diseas

González-García, Mauricio; Torres‐Duque, Carlos A.; Bustos, Adriana; Peña, Carol; Maldonado, Darío

doi:10.1378/chest.124.4_meetingabstracts.168s-b

Cited by 3 publications

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“…COPD related to chronic indoor (domestic) inhalation of wood smoke has similarities and differences with COPD due to cigarette smoking (68,91,92). Wood smoke-attributable COPD presents clinically with minimal emphysema as a chronic obstructive disease with persistent cough, phlegm, dyspnea, and cor pulmonale (93,94). The women with wood smoke-attributable COPD tend to be older, shorter, and have a greater body mass index than those with cigarette smokingattributable COPD (68,93); they also have milder reduction of CO diffusing capacity of the lung (DL CO ), a normal or near normal ratio of DL CO /alveolar volume (93,95), and minimal or no emphysema on high-resolution computed tomography (CT) of the chest (95).…”

Section: Copd Chronic Bronchitis Respiratory Symptoms and Lung Funmentioning

confidence: 99%

Biomass Fuels and Respiratory Diseases: A Review of the Evidence

Torres-Duque¹,

Maldonado²,

Pérez‐Padilla³

et al. 2008

Proceedings of the American Thoracic Society

417

266

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Globally, about 50% of all households and 90% of rural households use solid fuels (coal and biomass) as the main domestic source of energy, thus exposing approximately 50% of the world population-close to 3 billion people-to the harmful effects of these combustion products. There is strong evidence that acute respiratory infections in children and chronic obstructive pulmonary disease in women are associated with indoor biomass smoke. Lung cancer in women has been clearly associated with household coal use. Other conditions such as chronic obstructive pulmonary disease in men and tuberculosis could be also associated but evidence is scarce. According to estimates of the World Health Organization, more than 1.6 million deaths and over 38.5 million disability-adjusted life-years can be attributable to indoor smoke from solid fuels affecting mainly children and women. Interventions to suppress or reduce indoor exposure include behavior changes, improvements of household ventilation, improvements of stoves, and, outstandingly, transitions to better and cleaner fuels. These changes face personal and local beliefs and economic and sociocultural conditions. In addition, selection of fuels should consider cost, sustainability, and protection of the environment. Consequently, complex solutions need to be locally adapted, and involve the commitment and active participation of governments, scientific societies, nongovernmental organizations, and the general community.

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Section: Copd Chronic Bronchitis Respiratory Symptoms and Lung Funmentioning

confidence: 99%

Biomass Fuels and Respiratory Diseases: A Review of the Evidence

Torres-Duque¹,

Maldonado²,

Pérez‐Padilla³

et al. 2008

Proceedings of the American Thoracic Society

417

266

View full text Add to dashboard Cite

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“…Los afectados tienden a ser mujeres, mayores, de menor estatura, nacidas en área rural y con mayor índice de masa corporal (35,36) . Además, presentan menor reducción de la capacidad de difusión pulmonar a CO, engrosamiento de la pared bronquial en radiografías de tórax (36) y un mínimo o inexistente enfisema, visualizado a través de tomografía computarizada de alta definición, que aquellas con EPOC atribuible a tabaco (35,37) . Asimismo, presentan mayor hiperactividad bronquial a la prueba con metacolina que en mujeres con EPOC por tabaco (37) .…”

Section: Diferencias Entre La Enfermedad Pulmonar Obstructiva Crónica...unclassified

“…Además, presentan menor reducción de la capacidad de difusión pulmonar a CO, engrosamiento de la pared bronquial en radiografías de tórax (36) y un mínimo o inexistente enfisema, visualizado a través de tomografía computarizada de alta definición, que aquellas con EPOC atribuible a tabaco (35,37) . Asimismo, presentan mayor hiperactividad bronquial a la prueba con metacolina que en mujeres con EPOC por tabaco (37) . El consumo de tabaco produce una EPOC con más enfisema e hiperplasia de células caliciformes, mientras que la exposición a biomasa tiende a producir EPOC con fibrosis de las vías respiratorias pequeñas, antracosis e hiperplasia de la íntima de la arteria pulmonar (38) .…”

Section: Diferencias Entre La Enfermedad Pulmonar Obstructiva Crónica...unclassified

Enfermedad pulmonar obstructiva crónica por exposición al humo de biomasa

Lopez

Mongilardi

Checkley

2014

Rev Peru Med Exp Salud Publica

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En este artículo se discute la relación existente entre la enfermedad pulmonar obstructiva crónica (EPOC) y el humo de biomasa. Más de la mitad de la población utiliza biomasa como combustible principal, sobre todo en áreas rurales y en países en vías de desarrollo donde su uso llega hasta el 80%. La inhalación del humo de biomasa crea un estado inflamatorio crónico, que se acompaña de una activación de metaloproteinasas y una reducción de la movilidad mucociliar. Esto podría explicar la gran asociación existente entre la exposición a biomasa y EPOC, revelada por estudios observacionales y epidemiológicos provenientes de países en vías de desarrollo y de países desarrollados. En esta revisión exploramos también las diferencias entre la EPOC causada por tabaco y por biomasa, y encontramos que, a pesar de las diferencias fisiopatológicas, la mayoría de las características clínicas, calidad de vida y mortalidad fueron parecidas. En los últimos diez años se han realizado intervenciones para disminuir la exposición a biomasa mediante el uso de cocinas mejoradas y combustibles limpios, sin embargo, estas estrategias todavía no han sido exitosas debido a su incapacidad para reducir los niveles de contaminación a niveles recomendados por la Organización Mundial de la Salud, y por su falta de uso. Por lo tanto, hay una necesidad urgente de ensayos de campo aleatorios, cuidadosamente realizados, para determinar la verdadera gama de reducciones de contaminación potencialmente alcanzables, la probabilidad de su uso y los beneficios a largo plazo en la reducción

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Estudo comparativo de sintomas respiratórios e função pulmonar em pacientes com doença pulmonar obstrutiva crônica relacionada à exposição à fumaça de lenha e de tabaco

et al. 2008

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Comparative study of respiratory symptoms and lung function alterations in patients with chronic obstructive pulmonary disease related to the exposure to wood and tobacco smoke* Estudo comparativo de sintomas respiratórios e função pulmonar em pacientes com doença pulmonar obstrutiva crônica relacionada à exposição à fumaça de lenha e de tabaco AbstractObjective: To describe and analyze clinical symptoms and spirometric alterations of patients with chronic obstructive pulmonary disease (COPD) and history of exposure to wood and tobacco smoke. Methods: We retrospectively evaluated data related to 170 patients distributed into 3 groups: 34 exposed only to wood smoke, 59 patients exposed only to tobacco smoke and 77 patients exposed to both. Results: The groups did not differ significantly in terms of age (p = 0.225) or degree of exposure, considering each type of exposure in isolation or in combination (p = 0.164 and p = 0.220, respectively). Females predominated in the group exposed to wood smoke. There were no differences among the groups regarding respiratory symptoms (p > 0.05), and moderate dyspnea predominated in the three groups (p = 0.141). The group exposed to wood smoke presented higher percentages of forced expiratory volume in one second/forced vital capacity ratio and of forced expiratory volume in one second (p < 0.05). Positive results on bronchodilator testing occurred more frequently in the group exposed to tobacco smoke. The percentage of severe and extremely severe obstruction was significantly higher in the group exposed to tobacco smoke (44.1%) than in that exposed to wood smoke (11.8%; p = 0.006). Conclusions: Respiratory symptoms and pulmonary function alterations consistent with COPD were observed in the groups of patients exposed to wood smoke. However, those alterations were not as significant as the alterations observed in the groups exposed to tobacco smoke. This study emphasizes the importance of prospective studies in evaluating the risk of wood-smoke-related COPD in Brazil, as well as the need for preventive measures in this area.Keywords: Pulmonary disease, chronic obstructive; Smoking; Air pollution, indoor; Smoke. ResumoObjetivo: Descrever e analisar sintomas respiratórios e alterações espirométricas em pacientes portadores de doença pulmonar obstrutiva crônica (DPOC), com história de exposição à fumaça de lenha e de tabaco. Métodos: Foram avaliados retrospectivamente dados de 170 pacientes distribuídos em 3 grupos: 34 pacientes expostos somente à fumaça de lenha, 59 pacientes, somente à de tabaco e 77 pacientes expostos a ambas. Resultados: Os grupos não diferiram quanto a idade (p = 0,225) e grau de exposição, considerando cada tipo de exposição isoladamente ou em associação (p = 0,164 e p = 0,220, respectivamente). No grupo exposto à fumaça de lenha predominou o sexo feminino. Não houve diferença entre os grupos quanto à freqüência dos sintomas respiratórios (p > 0,05), e houve predominância de grau moderado de dispnéia nos três grupos (p = 0,141). O grupo exposto à fumaça de ...

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Airway Hyperresponsiveness in Wood Smoke Chronic Obstructive Pulmonary Diseas

Cited by 3 publications

References 0 publications

Biomass Fuels and Respiratory Diseases: A Review of the Evidence

Biomass Fuels and Respiratory Diseases: A Review of the Evidence

Enfermedad pulmonar obstructiva crónica por exposición al humo de biomasa

Estudo comparativo de sintomas respiratórios e função pulmonar em pacientes com doença pulmonar obstrutiva crônica relacionada à exposição à fumaça de lenha e de tabaco

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