Air spark-like plasma source for antimicrobial NO<sub><i>x</i></sub>generation

Pavlovich, Matthew J.; Ono, Taizo; Galleher, Connor; Curtis, Brandon; Clark, Douglas S.; Machala, Zdenko; Graves, David B.

doi:10.1088/0022-3727/47/50/505202

Cited by 86 publications

(71 citation statements)

References 38 publications

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“…The figure shows that the measured profiles correlated well with the number densities of NO and NO 2 . This also confirmed that the model produces results consistent with experimental observations, because in aqueous or humid environments, such as the afterglow‐sample interface in our setup, the NO X species were converted quickly to

{N O}_{2}^{-}

and

{N O}_{3}^{-}

, as reported in, for example.…”

Section: Resultssupporting

confidence: 90%

Effect of Additive Oxygen on the Reactive Species Profile and Microbicidal Property of a Helium Atmospheric Pressure Plasma Jet

Arjunan

Obrusník

Jones

et al. 2016

Plasma Process. Polym.

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Microbial inactivation by cold atmospheric plasmas has been a subject of tremendous research interest in recent years, in part, due to the ambiguity concerning the plasma factors responsible for bacterial inactivation. This work investigated the efficacy of an atmospheric‐pressure plasma jet ignited in either helium or helium/oxygen mixtures in inactivating Escherichia coli on agar. The correlation of data obtained from inactivation experiments and a 2D model describing the gas dynamics and afterglow chemistry showed that the inactivation mechanisms differed qualitatively between the two gas compositions. This work also provides insight into the reaction pathways that lead to the production and destruction of the key active species and illustrates the importance in these processes of admixing ambient air.

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{N O}_{2}^{-}

and

{N O}_{3}^{-}

, as reported in, for example.…”

Section: Resultssupporting

confidence: 90%

Effect of Additive Oxygen on the Reactive Species Profile and Microbicidal Property of a Helium Atmospheric Pressure Plasma Jet

Arjunan

Obrusník

Jones

et al. 2016

Plasma Process. Polym.

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“…Surface dielectric barrier discharges operating in air were reported to generate on the order of hundreds to thousands of ppm of both NO and NO 2 in confined spaces next to the grounded electrode . Spark and glow‐type discharges in air can create even higher concentrations rapidly …”

Section: Air Plasma Rons and Plasma–water Interactionmentioning

confidence: 99%

Reactive Species from Cold Atmospheric Plasma: Implications for Cancer Therapy

Graves

2014

Plasma Processes & Polymers

254

192

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Cold atmospheric plasmas (CAP) formed in air generate reactive oxygen and nitrogen species (RONS). RONS are biologically and therapeutically active agents and experimental evidence suggests that air plasmas shrink tumors by increasing oxidative and nitrosative stress on neoplastic tissue. Most mainline anti‐cancer therapies – including ionizing radiation and chemotherapies – also operate primarily via this pro‐oxidant, oxidative, and nitrosative stress mechanism. The main disadvantage of these conventional therapies is the development of treatment‐resistant cells. A key question for plasma cancer therapies is therefore whether or not cold plasma will lead to similar oxidative stress resistance. However, there are hints that combining nitrosative stress with oxidative stress via air plasma might avoid this problem. Plasma‐based cancer treatment may be a powerful and practical anti‐cancer agent, acting either alone or in combination with other therapies.

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“…Thus, other reactive gaseous species, photons, and so forth must be at work. In particular, reactive oxygen and nitrogen species (RONS) have attracted a great deal of attention for applications in plasma medicine …”

Section: Introductionmentioning

confidence: 99%

Biodeactivation of Lipopolysaccharide Correlates with Surface‐Bound NO₃ After Cold Atmospheric Plasma Treatment

Bartis

Luan

Knoll

et al. 2015

Plasma Processes & Polymers

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Cold atmospheric plasma (CAP) treatment of biological surfaces results in important changes of biological functions, but little knowledge on specific surface-chemical changes is available. We measured surface-bound NO 3 on polymer and biomolecular films after CAP treatment. An O 2 /N 2 -based surface microdischarge was used to deactivate lipopolysaccharide (LPS), an immune-stimulating biomolecule found in Gram negative bacteria. The observed LPS biodeactivation was highest for low N 2 concentrations in O 2 , increased roughly linearly with surface NO 3 , and then saturated. NO 3 was also observed after treatment by a very different source: an atmospheric pressure plasma jet operating with an Ar carrier gas. Thus, NO 3 formation is a generic surface chemical modification of these materials by CAP sources.

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Air spark-like plasma source for antimicrobial NO_xgeneration

Cited by 86 publications

References 38 publications

Effect of Additive Oxygen on the Reactive Species Profile and Microbicidal Property of a Helium Atmospheric Pressure Plasma Jet

Effect of Additive Oxygen on the Reactive Species Profile and Microbicidal Property of a Helium Atmospheric Pressure Plasma Jet

Reactive Species from Cold Atmospheric Plasma: Implications for Cancer Therapy

Biodeactivation of Lipopolysaccharide Correlates with Surface‐Bound NO₃ After Cold Atmospheric Plasma Treatment

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Air spark-like plasma source for antimicrobial NOxgeneration

Cited by 86 publications

References 38 publications

Effect of Additive Oxygen on the Reactive Species Profile and Microbicidal Property of a Helium Atmospheric Pressure Plasma Jet

Effect of Additive Oxygen on the Reactive Species Profile and Microbicidal Property of a Helium Atmospheric Pressure Plasma Jet

Reactive Species from Cold Atmospheric Plasma: Implications for Cancer Therapy

Biodeactivation of Lipopolysaccharide Correlates with Surface‐Bound NO3 After Cold Atmospheric Plasma Treatment

Contact Info

Product

Resources

About

Air spark-like plasma source for antimicrobial NO_xgeneration

Biodeactivation of Lipopolysaccharide Correlates with Surface‐Bound NO₃ After Cold Atmospheric Plasma Treatment