Air pollution and long-term risk of hospital admission due to chronic obstructive pulmonary disease exacerbations in Poland: a time-stratified, case-crossover study

Dąbrowiecki, Piotr; Chciałowski, Andrzej; Dąbrowiecka, Agata; Piórkowska, Anna; Badyda, Artur

doi:10.20452/pamw.16444

Cited by 6 publications

(4 citation statements)

References 45 publications

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“…Tobacco smoking, the first known cause of COPD, and air pollution's roles in developing chronic respiratory diseases are still not marginal [110,111]. Strategies for reducing COPD incidence and the severity of the disease (including preventing AECOPD) may reduce the amount of severe AECOPD patients requiring an ICU admission, meaning a clear benefit for the patient's health but also representing a strategy for reducing the economic impacts of COPD management and ICU stays [112][113][114][115][116][117][118][119]. Future research is needed to explore all these unmet questions about COPD.…”

Section: Discussionmentioning

confidence: 99%

COPD Exacerbation: Why It Is Important to Avoid ICU Admission

Prediletto

Giancotti

Nava

2023

JCM

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Chronic obstructive pulmonary disease (COPD) is one of the major causes of morbidity and mortality worldwide. Hospitalization due to acute exacerbations of COPD (AECOPD) is a relevant health problem both for its impact on disease outcomes and on health system resources. Severe AECOPD causing acute respiratory failure (ARF) often requires admission to an intensive care unit (ICU) with endotracheal intubation and invasive mechanical ventilation. AECOPD also acts as comorbidity in critically ill patients; this condition is associated with poorer prognoses. The prevalence reported in the literature on ICU admission rates ranges from 2 to 19% for AECOPD requiring hospitalization, with an in-hospital mortality rate of 20–40% and a re-hospitalization rate for a new severe event being 18% of the AECOPD cases admitted to ICUs. The prevalence of AECOPD in ICUs is not properly known due to an underestimation of COPD diagnoses and COPD misclassifications in administrative data. Non-invasive ventilation in acute and chronic respiratory failure may prevent AECOPD, reducing ICU admissions and disease mortality, especially when associated with a life-threating episode of hypercapnic ARF. In this review, we report on up to date evidence from the literature, showing how improving the knowledge and management of AECOPD is still a current research issue and clinical need.

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Section: Discussionmentioning

confidence: 99%

COPD Exacerbation: Why It Is Important to Avoid ICU Admission

Prediletto

Giancotti

Nava

2023

JCM

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“…This findings were similar to the previous studies. Dabrowiecki P et al 20 reported that during 21 days after exposure, an increase of 10 μg/m 3 in SO 2 and PM 10 was associated with an increase of 14.5% (95% CI: 3.8–26.2%) and 2.8% (95%CI: 0.8–4.9%) in COPD hospital admissions, respectively. Ghanbari et al 21 reported that during 1 year exposure, an increase of 10 μg/m 3 in SO 2 was associated with an increase of 0.5% (95% CI: 0%–1%) in COPD hospital admissions.…”

Section: Discussionmentioning

confidence: 99%

“…Numerous epidemiological studies have demonstrated that short‐ and long‐term exposure to air pollution is associated with COPD hospital admissions, acute exacerbation and mortality. 5 , 6 , 7 Dong et al 8 demonstrated that a 10‐μg/m 3 increase in PM 10 , SO 2 and NO 2 was associated with a 0.25% (95%CI: 0.01–0.49%), 1.67% (95%CI: 0.54–3.93%) and 1.37% (95%CI: 0.25–2.51%) increase in COPD outpatient visits, respectively. Zhang et al 9 found that every 10‐μg/m 3 increase in pollutants, the majority of the summary estimates for COPD hospital admissions were in the order of (ozone 3) O 3 > (particulate matter with aerodynamic diameter ≤ 2.5 um) PM 2.5 > NO 2 > PM 10 > SO 2 .…”

Section: Introductionmentioning

confidence: 99%

Long‐term effects of air pollution on hospital admissions and mortality for chronic obstructive pulmonary disease in Beijing, China

Zhu

Chen

2023

Clinical Respiratory J

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Objective We aimed to clarify the association between air pollution and hospital admissions for chronic obstructive pulmonary disease (COPD) and mortality in Beijing, China. Methods In this retrospective study, we recruited 510 COPD patients from 1 January 2006 to 31 December 2009. The patient data were obtained from the electronic medical records of Peking University Third Hospital in Beijing. Air pollution and meteorological data were obtained from the Institute of Atmospheric Physics of the Chinese Academy of Sciences. Monthly COPD hospital admissions, mortality and air pollution data were analysed using Poisson regression in generalised additive models adjusted for mean temperature, pressure and relative humidity. Results There were positive correlations between sulfur dioxide (SO2), particulate matter with an aerodynamic diameter ≤ 10 μm (PM10) and COPD hospital admissions in the single‐pollutant model. An increase of 10 μg/m3 in SO2 and PM10 were associated with an increase of 4.053% (95% CI: 1.470–5.179%) and 1.401% (95%CI: 0.6656–1.850%) in COPD hospital admissions. In the multiple‐pollutant model [SO2 and nitrogen dioxide (NO2) combinations], there was only a positive correlation between SO2 and COPD hospital admissions. An increase of 10 μg/m3 in SO2 were associated with an increase of 1.916% (95% CI: 1.118–4.286%) in COPD hospital admissions. There was no correlation between three pollutant combinations and COPD hospital admissions. We did not find correlations between air pollution and COPD mortality in either single‐ or multiple‐pollutant models. Conclusions SO2 and PM10 may be important factors for the increase in COPD hospital admissions in Beijing, China.

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“…Ambient air pollution could be linked to 8% to 10% of COPD admissions. [7] Another vulnerability caused by air pollution that calls for a serious concern, includes intra-uterine exposure to air pollutants and specially its effects on prenatal development. During both the prenatal and postnatal period, the window of vulnerability lies between the growth and developmental phases of the respiratory system of a fetus and extends till early infancy.…”

Section: Letter To the Editormentioning

confidence: 99%

The Invisible Threat: Urban Pollution’s Silent Assault on Respiratory Well-being

Khan,

Ghani,

Ahmad

et al. 2023

Preprint

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The detrimental impact of air pollution on human health is a growing concern, particularly in urban areas. Various factors, including industrial activities, traffic emissions, wildfires, and domestic heating, have led to the release of harmful pollutants such as PM2.5, PM10, NO2, SO2, NO, and O3, which exacerbate respiratory risks. Those diagnosed with respiratory conditions like Asthma, bronchitis, URTI, pneumonia, COPD, and Lung Tuberculosis are especially vulnerable to these pollutants. Air pollution contributes to both acute and chronic respiratory events. Acute exposure can result in respiratory diseases or worsen chronic conditions like COPD. Socioeconomic status is closely linked to the prevalence of lung tuberculosis, particularly in areas with high air pollution. Studies highlight the impact of air pollutants on vulnerable populations, such as children in urban households exposed to unclean fuels and the association with respiratory symptoms. Emergency room visits for asthma in children and the elderly reveal the delayed and immediate effects of different pollutants, emphasizing the need for air quality control. In addition to exacerbating chronic conditions, air pollution during prenatal and postnatal periods poses risks to fetal lung development. Maternal exposure to pollutants, including tobacco smoke, increases the risk of respiratory dysfunction in children. Preventive measures, such as prenatal counseling and awareness campaigns for vulnerable populations, are essential to mitigate the impact of air pollution. Furthermore, reducing emissions from industries and vehicles is crucial for improving air quality and safeguarding public health. Extensive research in this field is imperative to address this pressing environmental and health issue. Most importantly, prenatal genetic alterations are a new area of research for silent assault by air pollution that requires more literature.

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Air pollution and long-term risk of hospital admission due to chronic obstructive pulmonary disease exacerbations in Poland: a time-stratified, case-crossover study

Cited by 6 publications

References 45 publications

COPD Exacerbation: Why It Is Important to Avoid ICU Admission

COPD Exacerbation: Why It Is Important to Avoid ICU Admission

Long‐term effects of air pollution on hospital admissions and mortality for chronic obstructive pulmonary disease in Beijing, China

The Invisible Threat: Urban Pollution’s Silent Assault on Respiratory Well-being

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