Aging affects motor learning but not savings at transfer of learning

Seidler, Rachael D.

doi:10.1101/lm.394707

Cited by 97 publications

(80 citation statements)

References 36 publications

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“…This deficit becomes progressively evident with increasingly complex motor tasks (YORDANOVA et al, 2004). Another study found motor acquisition deficit in older adults; however, they exhibit normal transfer of learning, indicating that motor acquisition and transfer are distinct processes, affected differently by age (SEIDLER, 2007). All the results found to date show that the causes of reduced motor learning are multifactorial.…”

Section: Introductionmentioning

confidence: 70%

Maze test: an instrument to evaluate age-related cognitive and motor changes in humans

Sousa

Oliveira

Campos

2013

Revista Brasileira De Ciências Do Envelhecimento Humano

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Changes in cognitive and motor ability performance due to advancing age can compromise daily activities. It is important to determine if the maze test can be sensitive to the cognitive or motor alterations of normal ageing. This, the aim of the study was to verify age-related differences in executive function, learning and short-time memory by means of the maze test. Participated 80 healthy individuals, 40 young people (22 ± 2 years) and 40 elderly individuals (67 ± 5 years), underwent a health and cognitive evaluation (Mini Mental State Examination). Participants were timed solving thirty mazes, and another 15 minutes later. The data were analyzed by ANOVA and multiple linear regression. The elderly subjects took longer to solve the mazes, suggesting difficulties in executive function; learning took place in the first trials and a short-time memory deficit occurred. A correlation was observed between the cognitive and maze test (r = -0.320; p = 0.003). Age was the only predictive factor of performance. It is suggested that the maze test may contribute to the monitoring of premature cognitive and motor alterations in the elderly.

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Section: Introductionmentioning

confidence: 70%

Maze test: an instrument to evaluate age-related cognitive and motor changes in humans

Sousa

Oliveira

Campos

2013

Revista Brasileira De Ciências Do Envelhecimento Humano

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“…This may increase the accurate diagnosis of MCI among elderly population with low levels of education. These data add to the growing literature examining the relationships between sensorimotor and cognitive function decline with aging [35,36,37,38,39,40]. …”

Section: Discussionmentioning

confidence: 90%

Mild Cognitive Impairment Is Associated with Impaired Visual-Motor Planning When Visual Stimuli and Actions Are Incongruent

2011

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Background/Aims: This study examined cognitive-motor integration in adults with mild cognitive impairment (MCI). Previously, we showed that the performance of early-stage Alzheimer’s disease patients declined significantly as a visually-guided movement went from having a standard mapping (vision and action spatially aligned) to having a non-standard mapping (vision and action incongruent). The present study extends this line of research by examining the performance of individuals affected by MCI. Methods: The participants made finger movements over a clear touchscreen placed in two separate spatial planes to either constantly present or remembered visual targets. These spatial plane conditions were repeated with the direction of cursor motion rotated 180° from that of hand motion. We also tested an ‘arbitrary’ condition where symbols instructed the participants to move their hand in certain directions. Results: We observe that adults with MCI took significantly longer to plan movements requiring intermediate levels of non-standard mapping, relative to healthy older adults. Conclusions: These data suggest that movements requiring rule integration is affected even in individuals at a very early stage of cognitive decline. Cognitive-motor integration may provide a sensitive means to detect functional difficulty in early cognitive impairment.

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“…These interactions between experiences can be positive or negative, and were studied extensively in connection with education, psychology, and motor learning, but very little is known about the relevant neuronal substrates (Seidler 2007). From a temporal perspective, learning can be divided into an immediate "on-line" acquisition phase and an "off-line" consolidation phase (Balas et al 2007).…”

mentioning

confidence: 99%

Facilitation of taste memory acquisition by experiencing previous novel taste is protein-synthesis dependent

Merhav¹,

Rosenblum²

2008

Learn. Mem.

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Very little is known about the biological and molecular mechanisms that determine the effect of previous experience on implicit learning tasks. In the present study, we first defined weak and strong taste inputs according to measurements in the behavioral paradigm known as latent inhibition of conditioned taste aversion. We then demonstrated that a strong novel taste input facilitated acquisition of the memory of subsequent weak taste input in inverse correlation with the time interval between the inputs. However, not only was a strong taste input unable to rescue an immediately subsequent strong taste input when the gustatory cortex was under the influence of the protein-synthesis inhibitor, anisomycin, but the effect of the interaction was to reduce the variation among individual taste memories. Taken together, these results demonstrate that taste memory facilitation, induced by previously experiencing a different unimodal taste input, depended on time, novelty, and directionality. Moreover, the results imply that learning is enhanced on the level of acquisition but not of molecular consolidation.

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Aging affects motor learning but not savings at transfer of learning

Cited by 97 publications

References 36 publications

Maze test: an instrument to evaluate age-related cognitive and motor changes in humans

Maze test: an instrument to evaluate age-related cognitive and motor changes in humans

Mild Cognitive Impairment Is Associated with Impaired Visual-Motor Planning When Visual Stimuli and Actions Are Incongruent

Facilitation of taste memory acquisition by experiencing previous novel taste is protein-synthesis dependent

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