Aggressive unicystic ameloblastoma affecting the posterior mandible: late diagnosis during orthodontic treatment

Lopes, Sérgio Lúcio Pereira de Castro; Flores, Isadora Luana; Gamba, Thiago de Oliveira; Ferreira-Santos, Rívea Inês; Moraes, Mari Eli Leonelli de; Cabello, Aline Alvarez; Moutinho, Paula Nascimento

doi:10.5125/jkaoms.2017.43.2.115

Cited by 4 publications

(7 citation statements)

References 10 publications

(30 reference statements)

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“…Cone-beam computed tomography scans are mandatory for three-dimensional lesion demarcation, including accurate assessment of relationships with skull structures. 25 , 26 Other tooth and bone effects were identified in 10% and 20% of cases, respectively, because of CBCT imaging. This highlights the importance of CBCT as an imaging modality in cases of AB.…”

Section: Discussionmentioning

confidence: 99%

The radiologic progression of ameloblastomas

Merbold,

Smit,

Ker-Fox

et al. 2023

South African Journal of Radiology

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Background: In developing countries, many diagnosed cases of ameloblastoma (AB) have a significant delay in receiving treatment because of patient factors and healthcare facility constraints.Objectives: The radiologic progression of ABs with delayed treatment was analysed using panoramic radiographs and cone-beam computed tomography imaging.Method: Histopathologically confirmed cases of AB with follow-up radiographs indicating no treatment were retrospectively reviewed over a study period of 10 years. Fifty-seven cases with 57 initial and 107 follow-up radiographs were included. Each follow-up radiograph was analysed for changes in borders, locularity, effects on surrounding structures and lesion size.Results: There was a general increase in poorly-demarcated lesions, with seven cases transforming from an initial unilocular to a multilocular appearance. At follow-up, there was an increase in cortical thinning and cortical destruction. Ameloblastomas presented with a three-fold increase in average size from the initial to follow-up visits. Regression analysis showed a statistically significant relationship between lesion duration and length (p = 0.001). A statistically significant relationship existed between duration and overall lesion dimensions when only the first and last observations per patient were used (p = 0.044).Conclusion: Considering the aggressive nature and unlimited growth potential, ABs with delayed treatment may show extensive growth, complicating their eventual management.Contribution: This study aimed to raise awareness of the importance of the timeous management of patients with AB by highlighting the detrimental effects of delayed treatment.

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Section: Discussionmentioning

confidence: 99%

The radiologic progression of ameloblastomas

Merbold,

Smit,

Ker-Fox

et al. 2023

South African Journal of Radiology

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“…In addition, Pereira-Castro-Lopes et al (26) reported a case of a 20-year-old male presenting a significant ameloblastoma lesion occupying the right body and ramus of the mandible, causing tooth resorption. The patient had another radiograph taken 4 years before for orthodontic planning purposes.…”

Section: Discussionmentioning

confidence: 99%

Radiographic estimation of the growth rate of initially underdiagnosed ameloblastomas

Mariz

Andrade²,

Agostini³

et al. 2019

Med Oral

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Background To evaluate the specific growth rate (SGR) of ameloblastoma. Material and Methods Cases of ameloblastoma initially underdiagnosed (e.g. cases overlooked or diagnosed as reactive lesions) which had adequate radiographic documentation to evaluate their progression were retrospectively selected. Two panoramic radiographs were analyzed to determine the specific growth rate (SGR) of each tumor, defined as the logarithm of the ratio of final tumor area (when the diagnosis of ameloblastoma was made) to the initial tumor area (when the lesion was underdiagnosed), divided by the time interval between the radiographic images. The tumor area was measured using the software ImageJ. Results Twelve patients with mandibular ameloblastomas were selected, including 5 males and 7 females, with a mean age of 24.9 years (range: 14-61 years). In four cases, the lesion was associated with the crown of an impacted third molar. In three cases, it was initially diagnosed as a periapical lesion. Three cases were extrafollicular and were not noticed in the initial radiographs. Two cases were initially diagnosed as ameloblastoma, but the surgery was delayed for personal reasons. The mean interval of time between the two radiographic images was 4.3 years (range: 0.4-9 years). Based on our analysis, ameloblastoma grows in average 40.4% per year (range: 14.9-88.7%). Conclusions Ameloblastoma is a progressively growing tumor, but its growth rate seems to be smaller than initially reported in the literature. Better understanding the radiographic progression of ameloblastoma might improve its early diagnosis, management, and prognosis. Key words: Ameloblastoma, odontogenic tumors, growth rate, panoramic radiograph.

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“…Despite its clinicopathological subtypes, ameloblastoma is generally characterized by an aggressive potential for local invasion and a high tendency to recur, therefore, aggressive treatment through surgical resection is commonly recommended 5 . However, surgical resection of mandibular ameloblastoma can cause complications and functional, physical and psychological sequelae, especially in young patients.…”

Section: Introductionmentioning

confidence: 99%

Conservative treatment of large unicystic ameloblastoma in a young patient: a 7-year follow-up

De Freitas,

Lacerda-Santos,

De Andrade

et al. 2024

Braz. J. Hea. Rev.

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The unicystic ameloblastoma is an odontogenic tumor that is frequently found in young patients and usually affects the posterior region of the mandible. This paper aimed to describe a case report and 7-year follow-up of a young patient. The 12-year-old patient presented with increased volume in the lower third of the right hemiface with a duration of 6 months. Radiographic examination showed a unilocular radiolucent lesion extending along the body, angle and right mandibular ramus. An incisional biopsy was performed and a histological diagnosis of luminal unicystic ameloblastoma was obtained, opting for a conservative treatment with decompression and subsequent complete enucleation of the lesion. The patient has been under follow-up for 7 years, with a good evolution of the condition and without clinical and radiographic signs of recurrence of the lesion. Thus, it is ratified that timely conservative intervention and conservative surgical treatment should be the first choice for ameloblastoma management in young patients.

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Aggressive unicystic ameloblastoma affecting the posterior mandible: late diagnosis during orthodontic treatment

Cited by 4 publications

References 10 publications

The radiologic progression of ameloblastomas

The radiologic progression of ameloblastomas

Radiographic estimation of the growth rate of initially underdiagnosed ameloblastomas

Conservative treatment of large unicystic ameloblastoma in a young patient: a 7-year follow-up

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