Aggressive, undifferentiated sarcoma with widespread metastasis in a six-month-old Neopolitan mastiff

Sanders, NA; Kerlin, RL; Dambach, Dm

doi:10.5326/15473317-32-2-97

Cited by 6 publications

(13 citation statements)

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“…On the basis of the clinical, radiographic and cytological findings our differential diagnosis included several types of neoplasia. Nevertheless, a definitive diagnosis should be based on histological and immunohistochemical examinations (Sanders et al 1996;Pawel et al 1997;Dixon and Head 1999;van Biervliet et al 2004;Penel et al 2008). From a pathological point of view, the present neoplasia presented an obvious mesenchymal origin.…”

Section: Fig 1: Clinical Aspect Of the Lesion Observed At Hospital Admentioning

confidence: 86%

“…2004). Sanders et al . (1996) reported a case of a dog with a poorly differentiated sarcoma in the cervical region with metastases to the mediastinum, pleura, lung, liver, kidney, omentum and mesentery.…”

Section: Discussionmentioning

confidence: 99%

“…The number of mitoses varies considerably. The histological diagnosis can be supported by immunohistochemistry; these tumour cells are positive to vimentin and negative to cytokeratin (Sanders et al 1996;Pawel et al 1997;van Biervliet et al 2004).…”

Section: Fig 2: (A) Left To Right Lateral Radiograph Showing the Invomentioning

confidence: 99%

“…No metastasis occurred in this horse nor in the other reported equine cases (Sweeney and Hendrickson 1989;Dixon and Head 1999;van Biervliet et al 2004). Sanders et al (1996) reported a case of a dog with a poorly differentiated sarcoma in the cervical region with metastases to the mediastinum, pleura, lung, liver, kidney, omentum and mesentery.…”

Section: Fig 2: (A) Left To Right Lateral Radiograph Showing the Invomentioning

confidence: 99%

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An undifferentiated sarcoma in the cervical region in a horse

Zani¹,

Zani

Borgonovo

et al. 2011

Equine Veterinary Education

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Summary An Italian Saddle Horse mare was admitted for a hard, nonpainful mass localised in the cervical region. Clinical and diagnostic investigations were performed, which were suggestive of a multilobulated ossifying mass of neoplastic origin. Due to poor prognosis the horse was subjected to euthanasia. Post mortem computed tomography, anatomopathological examination and immunohistochemistry were used to make a definitive diagnosis of undifferentiated sarcoma in the cervical region.

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Section: Fig 1: Clinical Aspect Of the Lesion Observed At Hospital Admentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Fig 2: (A) Left To Right Lateral Radiograph Showing the Invomentioning

confidence: 99%

Section: Fig 2: (A) Left To Right Lateral Radiograph Showing the Invomentioning

confidence: 99%

See 2 more Smart Citations

An undifferentiated sarcoma in the cervical region in a horse

Zani¹,

Zani

Borgonovo

et al. 2011

Equine Veterinary Education

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“…One report of an aggressive, undifferentiated sarcoma with metastasis in a young dog has been previously described [12]. This sarcoma occurred in the cervical neck region with metastasis to organs including the lungs, liver, and kidneys.…”

Section: Discussionmentioning

confidence: 99%

Poorly Differentiated Uterine or Cervical Sarcoma in a Young Dog

Cora

Neel

2011

Case Reports in Veterinary Medicine

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A 1.5 year old, female, spayed, Labrador retriever with a history of three abdominal surgeries within the previous two months presented to the North Carolina State University Veterinary Teaching Hospital for evaluation of a pelvic inlet mass causing fecal tenesmus, obstipation, and dysuria. Abdominal ultrasound revealed a caudal abdominal mass extending into the pelvic cavity. Cytologic evaluation of the mass showed a pleomorphic round to fusiform cell population with histiocytic and suppurative inflammation. The primary differential was neoplasia, but inflammation with cellular pleomorphism could not be excluded. Via histopathology and immunohistochemistry, a diagnosis of poorly differentiated sarcoma originating from the uterus or cervix with widespread intra-abdominal dissemination and metastasis was made. Sarcomas of any type are rare in young dogs with only sporadic cases of poorly or undifferentiated sarcomas reported. This case is a unique presentation of an aggressive, poorly differentiated sarcoma arising from the cervix or uterus in a young dog and illustrates the importance of histologic evaluation of surgically resected tissues that are abnormal in appearance.

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Soft tissue sarcomas in the pharyngeal region of a 5‐year‐old Quarter Horse mare

Pezzanite¹,

Devine²,

Toll³

2015

Equine Veterinary Education

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Summary This case report describes the identification of multiple soft tissue sarcomas in the pharyngeal region of a 5‐year‐old Quarter Horse mare. Diagnostic work‐up included physical examination, radiography, ultrasonography, endoscopic examination of upper airways and guttural pouch, and post mortem examination with histopathology. Humane euthanasia was indicated due to the chronicity of the condition, prognosis and financial constraints.

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Aggressive, undifferentiated sarcoma with widespread metastasis in a six-month-old Neopolitan mastiff

Cited by 6 publications

References 0 publications

An undifferentiated sarcoma in the cervical region in a horse

An undifferentiated sarcoma in the cervical region in a horse

Poorly Differentiated Uterine or Cervical Sarcoma in a Young Dog

Soft tissue sarcomas in the pharyngeal region of a 5‐year‐old Quarter Horse mare

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