Aggressive Pregnancy Tumor (Pyogenic Granuloma) with Extensive Alveolar Bone Loss Mimicking a Malignant Tumor: Case Report and Review of Literature

Abstract

MARTINS-FILHO SUMMARY:Oral pyogenic granuloma is a hyperplastic inflammatory lesion commonly associated to local irritation or trauma. Females are more affected than men probably due to the vascular effects of hormones that occur during puberty, pregnancy and menopause. In the pregnancy, the lesions are known as "pregnancy tumor" and tend to occur more frequently during the second and third trimester. In the oral cavity, histopathological examination is required for diagnosis, since the lesion is clinically indistinguishable from other reactive lesions and, usually, there is no evidence of bone involvement. The authors report a rare case of pyogenic granuloma with destruction of alveolar bone mimicking a malignant tumor in a 20-year-old woman in the 19 th week of pregnancy.

Bilateral lobular capillary- The aberrant twins

“…In a study done by Bhrugesh, Singh and Shenoy, cases of oral pyogenic granulomawith alveolar bone loss have been reported. MartinsFilho,reported a case of aggressivepyogenic granuloma with extensive alveolar bone loss that resembled a Malignant Tumor [9] . This emphasizes the need for histopathological evaluation, for any clinically or radiographically suspected lesion of pyogenic granuloma, to rule out the possibility of malignancy.…”

Aggressive invasive oral pyogenic granuloma: A case report

“…Bhrugesh, 12 Singh, 13 and Shenoy, 14 reported cases of oral pyogenic granuloma with alveolar bone loss. Martins-Filho, 15 reported aggressive pyogenic granuloma with extensive alveolar bone loss mimicking a Malignant Tumour. Saravana 16 in his review of 137 cases reported four patients with extensive bone loss and mobility of teeth.…”

ORAL HEALTH DURING PREGNANCY AND THE CLINIC APPEARANCE OF PREGNANCY TUMOR (Case Report)

“…In pregnancy tumors, the increased hormons return their normal ranges and tumor disappaers spontaneously after pregnancy. Pregnancy tumors are generally observed after first trimester 15,17,18 . Many published case studies have been reported on the observation of pregnancy tumors show that it can be seen in the third trimester likewise 2,3,19 .…”

“…For constructing therapy protocol, pregnancy should be taken into consideration. An expectant manner is followed but if the lesion causes bleeding, chewing disorders and does not recess after birth surgical treatment is indicated 15,19 . Operation during pregnancy is not a preferred therapy method since it shows recurrency.…”

“…It might have a stem or not 1,2 . This disease does not affect the bone tissue but in some cases mild bone resorption can be appeared in radiography 14,15 . Generally, it is not treated until pregnancy is ended however if it's painful and have excess bleeding and uncomfortable the patient, it can be surgically removed 1,2,4,,5,14,15 .…”