Aggressive manifestations of inflammatory pulmonary pseudotumor in children

Hedlund, Gary L.; Navoy, Joseph F.; Galliani, Carlos; Johnson, Walter H.

doi:10.1007/s002470050553

Cited by 85 publications

(71 citation statements)

References 14 publications

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“…[23][24][25][26][27][28] They are more frequently seen in the lower lobe of the right lung, and form a solitary, oval, and well defined lobulated mass that is peripherally located. [29][30][31] A mass lesion is located peripherally in 87% and centrally in 6%, and the lesions can present radiologically as multiple nodular (5%), pleural based, cavitary lesions (5%), or can present with lobar atelectasis (8%) or hilar lymphadenopathy (5%). 32,33 The World Health Organization's defini- tion is a lesion composed of a myofibroblastic spindle cell population accompanied by an inflammatory infiltrate of plasma cells, lymphocytes, and eosinophils.…”

Section: Discussionmentioning

confidence: 99%

Adult Inflammatory Myofibroblastic Tumor of the Trachea: Case Report and Literature Review

Öztuna

Pehlivanlar²,

Abul³

et al. 2012

Respir Care

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Inflammatory myofibroblastic tumor of the trachea is a rare benign tumor in adults. It is mostly seen before the age of 16. We describe a 20-year-old female patient who presented with stridor. She had a fixed obstruction on spirometry, and computed tomography and bronchoscopy confirmed tracheal thickening and stenosis below the vocal cords and bronchial wall thickening at the level of the carina. Bronchoscopic biopsy confirmed an inflammatory myofibroblastic tumor. She recovered after mechanical dilatation and resection via rigid bronchoscopy, followed by corticosteroid therapy.

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Section: Discussionmentioning

confidence: 99%

Adult Inflammatory Myofibroblastic Tumor of the Trachea: Case Report and Literature Review

Öztuna

Pehlivanlar²,

Abul³

et al. 2012

Respir Care

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“…Increased parenchymal density around the lesion has been noticed in some studies which are related to peribronchial fibrosis with a patchy distribution, peribronchial lymphoplasmacytic infiltrates and intraalveolar organization and edema. A poorly circumscribed lesion with spiculated margins causes difficulty in differentiating from malignant lesions 8,9 Aggressive features of inflammatory pseudotumor have been reported which include vertebral destruction, vascular invasion. 8 CT aids in the delineation of the geographical location of the lesion besides added value in studying the internal characteristics of the lesions.…”

Section: Radiologicmentioning

confidence: 99%

“…A poorly circumscribed lesion with spiculated margins causes difficulty in differentiating from malignant lesions 8,9 Aggressive features of inflammatory pseudotumor have been reported which include vertebral destruction, vascular invasion. 8 CT aids in the delineation of the geographical location of the lesion besides added value in studying the internal characteristics of the lesions. In two of our cases, CT demonstrated central necrosis.…”

Section: Radiologicmentioning

confidence: 99%

Inflammatory Myofibroblastic Tumor of Lung – Computed Tomographic Features in 20 Patients

Ghimire

Zhu

2012

Nep J Radiology

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Aim: To study the salient characteristic computed tomographic findings of inflammatory myofibroblastic tumor of lung. Materials and methods: We retrospectively reviewed the CT examinations of twenty histopathologically confirmed cases of inflammatory myofibroblastic tumor of lung and analyzed the involvement, predominant location, pattern of presentation, shape, edge, pattern and degree of enhancement and any atypical findings in those cases. Results: Fourteen cases presented as pulmonary nodules among which twelve as solitary while two cases as multiple pulmonary nodules. Six cases presented as masses. The location was in the parenchyma of the lung among all cases except two masses that were predominantly mediastinal and endobronchial respectively. All nodules demonstrated mild enhancement except one nodule showed moderate and another one marked enhancement. Four masses demonstrated mild enhancement whearas one showed moderate and another marked enhancement. Pleural surface abutting was noticed in one nodule and two masses. Stippled calcification was present in one mass while necrosis was noticed in two other cases that presented as mass. Mass were associated with consolidation in one and as cavity in another case. Conclusion: Although diagnosis of inflammatory myofibroblastic tumor of lung cannot be confirmed radiologically, certain features as presence of nodules or masses that enhance mildly in a patient with equivocal clinical and radiological presentation warrants its inclusion in the differential diagnosis.

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“…The tumor rarely undergoes malignant transformation. The potential for recurrence and focal invasion are reported in oncologic, surgical, and radiological literature (2)(3)(4). Reports and radiologic imaging of malignant transformation, however, are very few (5) and to our knowledge, this is the first report that provides imaging of distant metastasis.…”

mentioning

confidence: 90%

Malignant transformation of an abdominal inflammatory myofibroblastic tumor with distant metastases in a child

Ernst¹,

Bosch²,

Desprechins³

et al. 2011

Journal of the Belgian Society of Radiology

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Inflammatory myofibroblastic tumors (IMT) are lesions that mostly affect young adults and children. The tumor is made up of myofibroblasts and a mixed inflammatory infiltrate and rarely undergoes malignant transformation. We present a case of a 13-year-old boy with a pelvic mass diagnosed as IMT which underwent malignant transformation and metastasised to the liver. We report the ultrasound, computed tomography (CT) and magnetic resonance (MR) findings of this rare disorder.

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Aggressive manifestations of inflammatory pulmonary pseudotumor in children

Cited by 85 publications

References 14 publications

Adult Inflammatory Myofibroblastic Tumor of the Trachea: Case Report and Literature Review

Adult Inflammatory Myofibroblastic Tumor of the Trachea: Case Report and Literature Review

Inflammatory Myofibroblastic Tumor of Lung – Computed Tomographic Features in 20 Patients

Malignant transformation of an abdominal inflammatory myofibroblastic tumor with distant metastases in a child

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