Aggressive fibromatosis of the head and neck: a new classification based on a literature review over 40 years (1968–2008)

Kruse, Astrid L; Luebbers, Heinz T; Grätz, Klaus W.; Obwegeser, Joachim A.

doi:10.1007/s10006-010-0227-8

Cited by 39 publications

(33 citation statements)

References 36 publications

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“…The pathogenesis of this nonencapsulated lesion is still unknown (5) . The head and neck localization is not common and is mostly sporadic (6) .…”

Section: Discussionmentioning

confidence: 99%

“…During 40 years only 179 cases were reported (5) .Parotid localization has been very rarely treated; they have tried to separate it from that arising from other parts of the body (10) , due to its relation to its critical anatomical position (4) . The peak incidence is situating about the third decade (5,6) ; our patient was younger 24 years. The behavior of this tumor seems to be more aggressive in younger people.…”

Section: Discussionmentioning

confidence: 99%

“…Some authors report that both genders are equally affected (6) , others one reports a female predominance. No significant racial or ethnic distribution has been objectified (5) . The etiology is still unknown (7) .…”

Section: Discussionmentioning

confidence: 99%

“…It is a rare tumor that accounts for only 0, 03% of all neoplasm (4) with an annual incidence estimated at 2-4 cases /million / year (5) . Despite its benign histology, this tumor is characterized by infiltrative growth and the absence of proper capsule which explains the high incidence of local recurrence but without showing any metastasis (6) ; thus some authors classified it as a low-grade mesenchymal tumor or sarcoma (1,2) .…”

Section: Introductionmentioning

confidence: 99%

“…Despite its benign histology, this tumor is characterized by infiltrative growth and the absence of proper capsule which explains the high incidence of local recurrence but without showing any metastasis (6) ; thus some authors classified it as a low-grade mesenchymal tumor or sarcoma (1,2) . The localization in the head and neck was reported in 12% of cases of extra-abdominal fibromatosis (5) and seems to be more aggressive in this region due to the restricted anatomy and the recurrence rate following the surgical resection (5) .…”

Section: Introductionmentioning

confidence: 99%

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Desmoid Tumor of The Parotid Gland

Abir¹,

Monia²,

Abdelkéfi³

et al. 2017

IAM

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Desmoid tumor is a proliferation of a mesenchymal, fibroblastic or myofibroblastic tissue. It is a non-capsulated tumor. Despite its benign nature, desmoids tumor have an aggressive behavior.Its localization in the parotid gland has rarely been reported in the literature.The particularity of this location in the head and neck is the proximity of Vascularnervous structures, the facial nerve in the parotid location and the consequence, if affected, on the facial motility especially that this tumor often occurs in young people. The clinical presentation is often about a slow-growing mass characterized by being: painless, ill-defined, firm, non-inflammatory, deeply located, and fixed to the underlying structures. Treatments strategies, always made by a multidisciplinary committee, are based on the natural biological behavior of this deep fibromatosis which is unpredictable and variable. Surgery could be undergone every time it is radical. Radiotherapy could also be played. However, the most relevant point is that actually, most authors highlighted the conservative approach by the "wait and see" policy for primary as well as for recurrence of the disease after surgical resection or radiotherapy.

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“…The pathogenesis of this nonencapsulated lesion is still unknown (5) . The head and neck localization is not common and is mostly sporadic (6) .…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Desmoid Tumor of The Parotid Gland

Abir¹,

Monia²,

Abdelkéfi³

et al. 2017

IAM

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Desmoid tumors of the head and neck: A therapeutic challenge

et al. 2014

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Desmoid tumor, or aggressive fibromatosis, is a rare, histologically benign, fibroblastic lesion that infrequently presents in the head and neck. Desmoid tumors often grow locally, invasively, and may, in rare instances, be fatal secondary to invasion into critical structures, such as airway or major vessels. The most common treatment is surgery, but desmoid tumors are characteristically associated with a high local recurrence rate after resection. Although the margin status seems to be of importance, operations that avoid function loss and esthetic disfigurement should be the primary goal. The efficacy of postoperative radiotherapy is controversial. Its potential benefit should be carefully balanced against possible radiation-induced adverse effects. Alternative treatment modalities, such as primary radiotherapy and medical treatment or a wait-and-see policy, may be preferable to mutilating surgery. Considering all the aforementioned, it seems obvious that desmoid tumors of the head and neck present a therapeutic challenge and require an individualized approach.

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