Aggressive Angiomyxoma of the Spermatic Cord. Two Unusual Cases Occurring in Childhood

Carlinfante, Gabriele; Marco, Loredana De; Mori, Maurizio; Ferretti, Stefania; Crafa, Pellegrino

doi:10.1078/0344-0338-00025

Cited by 26 publications

(15 citation statements)

References 24 publications

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“…Vimentin stains are positive in the lesional cells, with variable staining for smooth muscle actin and desmin and negativity for S-100 protein and CD34. Of two patients with significant follow-up, one was disease free at 30 months after surgical excision, 308 and another experienced recurrence in the opposite testis at 2 months. 310 Other benign paratesticular tumors of soft tissue origin Occasional benign soft tissue tumors are encountered in the paratestis of children.…”

Section: Aggressive Angiomyxomamentioning

confidence: 95%

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Testicular and paratesticular tumors and tumor-like lesions in the first 2 decades

Ulbright

Young

2014

Seminars in Diagnostic Pathology

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Section: Aggressive Angiomyxomamentioning

confidence: 95%

“…[308][309][310] Two involved the spermatic cord, one the paratestis without further specification, and two the "scrotum," without further localization. On gross examination the tumors usually have a gray-white, gelatinous, glistening appearance.…”

Section: Aggressive Angiomyxomamentioning

confidence: 98%

Testicular and paratesticular tumors and tumor-like lesions in the first 2 decades

Ulbright

Young

2014

Seminars in Diagnostic Pathology

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“…4 Although AAM has always been described as only locally infiltrative, in 1999 Siassi et al 6 described a case of an AAM of the pelvis that metastasized to the mediastinum and lungs in a 63-year-old woman. Macroscopically, AAM is a large, grossly gelatinous, poorly circumscribed 7 and locally infiltrative tumor. 4 Its microscopic features are myxoid stroma, low cellularity and vessels of varying size, sometimes with hyaline thick walls.…”

Section: Discussionmentioning

confidence: 99%

“…4 Its microscopic features are myxoid stroma, low cellularity and vessels of varying size, sometimes with hyaline thick walls. 7 Cellularity is usually low, and mitoses are not seen. 6 The anomalous muscular artery is very specific for diagnosis of AAM, and is the major histological difference form angiomyofibroblastoma.…”

Section: Discussionmentioning

confidence: 99%

Massive recurring angiomyxoma of the scrotum in a obese man

et al. 2011

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Aggressive angiomyxoma (AAM) is a rare mesenchymal benign myxoid tumor, characterized by locally infiltrative nature and high recurrence rate. AAM occurs almost exclusively in adult females, arising from the soft tissue of the pelvic region: to our knowledge, only 43 cases occurring in men have been reported. We report a case of massive recurrence of scrotal AAM in a 46-year-old obese man, who already underwent surgery for the same disease in 2004 and 2005. The mass had a circumference of 106 cm and weighted 30 kg. It was impossible to appreciate the testes and to find the penis. The patient underwent scrotal resection, bilateral orchidopexia and transposition of the penis, by means of a preputial flap. Residual scrotal skin was modeled in order to create a neoscrotum, where the testes were placed and secured with interrupted sutures. Histologic examination showed diffuse angiomyxoma-like lipomatosis. After three months, the patient presented with local relapse which also involved the external urethral orifice.

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“…To date, AAM has been reported very rarely in men and children. Recently two children with AAM in the spermatic cord and two children with AAM in the scrotum have been reported [1,3]. However, there is no report in the literature of AAM in the scrotum of a child with chronic renal failure (CRF).…”

Section: Introductionmentioning

confidence: 97%

Aggressive angiomyxoma in a child with chronic renal failure

et al. 2005

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Aggressive angiomyxoma (AAM) is a rare and nonmetastasizing soft-tissue tumor predominantly found in the female pelvis and perineum. It has a high risk of local recurrence. We report the unusual case of a 15-year-old boy with an AAM presenting as a slowly enlarging scrotal mass. The patient had had chronic renal failure since 1997 and had needed hemodialysis for the previous 11 months. He presented with a 12-month history of a nontender soft mass in the right scrotum. Ultrasound examination revealed a solid mass in the scrotum. After surgical resection, pathological analysis disclosed spindle-shaped neoplastic cells widely separated by a myxoid stroma rich in collagen fibers and prominent irregularly shaped blood vessels; the histological examination confirmed an AAM.

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Aggressive Angiomyxoma of the Spermatic Cord. Two Unusual Cases Occurring in Childhood

Cited by 26 publications

References 24 publications

Testicular and paratesticular tumors and tumor-like lesions in the first 2 decades

Testicular and paratesticular tumors and tumor-like lesions in the first 2 decades

Massive recurring angiomyxoma of the scrotum in a obese man

Aggressive angiomyxoma in a child with chronic renal failure

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