Aggregation-induced emission photosensitizer microneedles for enhanced melanoma photodynamic therapy

Abstract

The incidence and mortality rates of skin melanoma have been increasing annually. Photodynamic therapy (PDT) enables effective destruction of tumor cells while minimizing harm to normal cells. However, traditional photosensitizers...

Construction of glutathione-responsive paclitaxel prodrug nanoparticles for image-guided targeted delivery and breast cancer therapy

“…26,27 In recent years, uorescent nanoparticles based on AIE active chromophores have turn into a new generation of biological imaging nanoparticles. 28 It will be very interesting to develop uorescent nano-prodrug composed of luminophor with AIE characteristics as alternative uorescent materials for cell imaging and drug delivery monitoring.…”