Aggregation-enhanced emission of metal nanoclusters triggered by peptide self-assembly and application in chymotrypsin inhibitor screening

Photofunctional Gold Nanocluster Composites for Bioapplications

“…Thus, the fluorescence response can be utilized for screening and assessing CHT inhibitors such as epigallocatechin gallate, tannic acid, oleanolic acid, and ursolic acid. 46 AuNC Composites for Diverse Therapies. The photothermal effect of AuNCs relies on their ability to absorb light energy and convert it into heat, resulting in the thermal killing of cells.…”

“…However, chymotrypsin (CHT) can degrade the FF, causing a reduction in the AIE effect within the AuNC nanocomposites. Thus, the fluorescence response can be utilized for screening and assessing CHT inhibitors such as epigallocatechin gallate, tannic acid, oleanolic acid, and ursolic acid …”

Construction of logic gate computation for the assay of the nerve agent sarin based on an AChE-based dual-channel sensing system

“…GSH-Au NCs was synthesized according to literature. 22 Freshly prepared aqueous solutions of GSH (1.5 mL, 100 mM) and HAuCl 4 (5 mL, 20 mM) were mixed with 43.5 mL of ultrapure water and then heated at a 70 °C under gentle stirring (500 rpm) for 24 h. Finally, the resulting solution was diluted ten-fold with water and kept in the dark at 4 °C until use.…”

Origin of luminescence properties and synthetic methods for gold- and bimetallic gold-based nanomaterials

“…Recently, several reports have demonstrated the AIE effect in AuNPs, which were utilized as fluorescent sensors and in bioimaging. [119][120][121][122][123][124][125] Recent reviews on the aggregation and self-assembly of nanoclusters shed light on the nanoscale forces/interactions such as dipolar attraction, van der Waals interactions, electrostatic interactions, p-p stacking, and metallophilic interactions, which can initiate the aggregation or assembly process in nanoclusters. 11,126,127 (iii) Influence of oxidation state of Au.…”