Age-specific reference ranges for prostate specific antigen-total and free in patients with prostatitis symptoms and patients at risk

Abstract

Because of the greater variability at older ages, the 95th percentile increased faster than the median, the following age-specific reference ranges of TPSA and FPSA for patients with prostatism symptoms were as follows: 3.1 and 0.7 ng/ml for the age group 40-49 years, 4.4 and 0.89 ng/ml for the age group 50-59 years, 5.6 and 1.3 ng/ml for the age group 60-69 years, and 6.3 and 1.8 ng/ml for age group 70-79 years. There was a continuous increase in TPSA and FPSA means and medians with significant correlation (P<0.001, P<0.005) and advancing age group. The aim of this study was to find out age-specific values and ranges of TPSA and FPSA in patients with prostatism symptoms to ensure low false-positive biopsy rates.

Study on Early Prostate Cancer Antigen (EPCA) and existent risk factors of prostate cancer, Sudan: A case-control study

“…This is consistent with many of the results of studies conducted by Batikhi. which organized surveys in many different residential areas to define the role of obesity in the incidence of cancer [18]. Also, our results are similar in conclusion to study that included a population of older veterans [19].…”

Differentiation of Prostatitis and Prostate Cancer by Using Diffusion-weighted MR Imaging and MR-guided Biopsy at 3 T

“…MRguided biopsy was performed in male patients with (a) an elevated PSA level (.4 ng/mL), (b) family history of PCa, (c) suspicion for PCa based on diagnostic MR examination of the pelvis, and (d) at U rologists often face the dilemma of treating a patient in whom there is a high suspicion for prostate cancer (PCa) based on an elevated prostate-specific antigen (PSA) level (1)(2)(3). Benign prostatic hyperplasia can also lead to elevated PSA levels and is not always associated with clinical symptoms.…”