Age shift: Breast cancer is occurring in younger age groups - Is it true?

Chopra, Brinder; Kaur, Vaneet Inder; Singh, Kamaljit; Verma, Minni; Singh, Sukhpreet; Singh, Ajmer

doi:10.4103/2278-0513.142652

Cited by 77 publications

(64 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The reason is increasing urbanization and westernization associated with changing lifestyle and food habits. Studies show that the disease peaks at 40-50 years in Indian women with a peak relative proportion between 45 and 49 years [5,6] which is similar to the median age of presentation at our institution which is 49 years. Indian women having breast cancer are found a decade younger in comparison to western women [7,8] .…”

Section: Discussionsupporting

confidence: 51%

Analysis of Demographic Characteristics and Treatment Outcome of Breast Cancer Patients in a Tertiary Cancer Centre

Velappan¹,

Shumugam²

2017

IOSR JDMS

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 51%

Analysis of Demographic Characteristics and Treatment Outcome of Breast Cancer Patients in a Tertiary Cancer Centre

Velappan¹,

Shumugam²

2017

IOSR JDMS

View full text Add to dashboard Cite

“…A study by Chopra et al also highlights around 61% breast cancer cases in the premenopausal age group. [11] In this study the most common molecular subtype was luminal A representing 37%, which is compatible with study done by Munjal K et al [12] and Fan et al [13] but much lower than Yang et al [14] and Spitale A et al [15] which showed around 70% of the patients to be of Luminal A type.…”

Section: Discussionsupporting

confidence: 80%

Molecular subtyping of invasive breast cancer and its relation to common risk factors: a hospital based study

Chauhan¹,

Trivedi²,

Panjwani³

et al. 2017

Int J Recent Sci Res

View full text Add to dashboard Cite

Background: Breast cancer is the most common cancer among Indian women. Majority of our patients do not have the traditional risk factors, and present in a locally advanced stage which progresses despite treatment. Studies have shown that it can be stratified in molecular subtypes by using a panel of immunohistochemical markers for estrogen, progesterone and HER 2neu receptor, which is closely related to its prognosis. Aim: This study was done to determine the prevalence of various molecular subtypes in our patients and its relation to various risk factors. Materials and Method: 446 breast cancer patients treated at Mahavir Cancer Sansthan, Patna from January 2015 toDecember 2015 were retrospectively analysed for their age, parity, history of breast feeding, menopausal status, height, weight, ER, PR & HER2neu receptor status. They were then classified in four molecular subgroups, Luminal A, Luminal B, Triple negative and HER2neu positive cancers and its relation to menopausal status and body mass index was analysed. Observations and Results: 68.38% patients were premenopausal with a mean age of 47.12 years. 24.38% patients were obese or overweight, with an average BMI of 22.38. Luminal A subtype followed by Triple Negative subtype was found in 37% and 29% of the patients respectively. The prevalence of Triple Negative subtype was more in premenopausal and overweight patients. Conclusion: Overall prevalence of triple negative subtype in our patient population is high esp. among premenopausal overweight patients.

show abstract

“…11 A study in India shows that there are two peaks in the age at diagnosis of breast cancer at 41-50 years and 51-60 years. 12 The latter peak is common with peak in western countries, but the peak at 41-50 years shows that the disease occurs at a younger age in Indian patients as compared to the west. Data of Delhi, India from 2001 to 2003 under national cancer registry program of ICMR recorded 529, 544, and 601 cases of breast cancer in age groups 40-44, 45-49, and 50-54 years respectively out of a total of 3777 breast cancer cases recorded.…”

Section: Discussionmentioning

confidence: 99%

Age distribution pattern of female breast cancer patients in Bangladesh- developing early and presenting late

et al. 2018

View full text Add to dashboard Cite

Background: Carcinoma of the breast is the most common malignancy in females. At present carcinoma breast is the leading cancer in Bangladesh and is competing cancer cervix in incidence. Epidemiological studies at regional and global levels suggest the occurrence of carcinoma breast at a younger, premenopausal age in Indian and Asian women as compared with western women. Knowledge of this factor emphasizes the need to modify the timing of modalities of detection of early carcinoma and its management. According to literature, majority of carcinoma breast cases in the western countries present in Stages I and II of the disease whereas in Bangladesh majority cases present in Stage III of the disease. The objective of this study is to observe age of occurrence of breast cancer and stage of cancer in SSMC and MH.Methods: A cross sectional observational study was conducted in 34 patients of histopathologically confirmed breast cancer.Results: Mean age of subjects was 46.24±7.4 years. Age distribution showed peaks at 41-50 years with 18 patients. This study shows that 82.35% of the total patients were having advanced carcinoma breast (Stage III, IV) and 77% of these patients were below 50 years of age.Conclusions: Breast cancer is increasingly occurring in younger age groups in Bangladesh when compared with western countries and a more aggressive nature of the disease strikes in their reproductive period suggesting the need for change in modalities of early cancer detection and adjusting preventive and therapeutic efforts. This small study may provocate thought for larger scale population study to evaluate the scenario in Bangladesh.

show abstract

Age shift: Breast cancer is occurring in younger age groups - Is it true?

Cited by 77 publications

References 1 publication

Analysis of Demographic Characteristics and Treatment Outcome of Breast Cancer Patients in a Tertiary Cancer Centre

Analysis of Demographic Characteristics and Treatment Outcome of Breast Cancer Patients in a Tertiary Cancer Centre

Molecular subtyping of invasive breast cancer and its relation to common risk factors: a hospital based study

Age distribution pattern of female breast cancer patients in Bangladesh- developing early and presenting late

Contact Info

Product

Resources

About