Age distribution pattern of female breast cancer patients in Bangladesh- developing early and presenting late

Abstract

Background: Carcinoma of the breast is the most common malignancy in females. At present carcinoma breast is the leading cancer in Bangladesh and is competing cancer cervix in incidence. Epidemiological studies at regional and global levels suggest the occurrence of carcinoma breast at a younger, premenopausal age in Indian and Asian women as compared with western women. Knowledge of this factor emphasizes the need to modify the timing of modalities of detection of early carcinoma and its management. According to literature, majority of carcinoma breast cases in the western countries present in Stages I and II of the disease whereas in Bangladesh majority cases present in Stage III of the disease. The objective of this study is to observe age of occurrence of breast cancer and stage of cancer in SSMC and MH.Methods: A cross sectional observational study was conducted in 34 patients of histopathologically confirmed breast cancer.Results: Mean age of subjects was 46.24±7.4 years. Age distribution showed peaks at 41-50 years with 18 patients. This study shows that 82.35% of the total patients were having advanced carcinoma breast (Stage III, IV) and 77% of these patients were below 50 years of age.Conclusions: Breast cancer is increasingly occurring in younger age groups in Bangladesh when compared with western countries and a more aggressive nature of the disease strikes in their reproductive period suggesting the need for change in modalities of early cancer detection and adjusting preventive and therapeutic efforts. This small study may provocate thought for larger scale population study to evaluate the scenario in Bangladesh.

Influence of Age, Estrogen receptor (ER),Progesterone receptor (PR) and Epidermal growth factor -2 (HER-2) in Breast Carcinoma Patient in correlation with Radionuclide Bone Scan – Single Institute Based Experience

“…Most of the patients in the study was in between 50-60 years and least patient was in age between 30-40 years and 70-80 years which was consistent with study conducted by Neesa et al (2018). They showed the similar findings, age range of their study subject was 32 to 81 years and least patient was in age group <40 years and >80 years (4). Another study conducted by Lee et al (2011) also found the similar results (5).…”

Effect of early rehabilitation on shoulder pain and disability after modified radical mastectomy

“…This result finding was in the same line with (Salehi et al, 2017) [36] who mentioned that the mean age at the time of diagnosis www.nursingjournal.net was 48.8 ±12.01. Also, (Nessa et al, 2018) [33] reported that the highest percentage of studied women was above 40 years. This finding may be justified that aging process is one of the most important risk factors of breast cancer because of the longer life expectancy, changes in reproductive patterns in women over 40 years, menopausal hormonal use, rising prevalence of obesity, and genetic damage (mutations) in the body at this age.…”

Molecular Analysis of Breast Cancer BRCA1 and BRCA2 in Southern Punjab

“…Its incidence in Pakistan is 2.5 times higher than that in neighboring countries like Iran and India [1]. The risk factors associated with breast cancer are age, family history, early menarche, nicotine consumption, 1 st child birth, physical inactivity and lack of awareness regarding the disease [8].…”