Age Dependent Secretion of LH and ACTH in Healthy Men and Patients with Erectile Dysfunction

Derouet, H.; Lehmann, Jan; Stamm, Bettina; Lühl, Christof; Römer, Dirk; Georg, Thomas; Isenberg, E.; Gebhardt, Th.; Stöeckle, Michael

doi:10.1016/s0302-2838(01)00033-1

Cited by 14 publications

(10 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The active forms of cortisol have been shown to have signifi cant negative correlations with IIEF domains [ 8 ] . This fi nding contrasts with the results of another study that found no differences in the cortisol levels of individuals with and without ED [ 17 ] . Our Low dose, 5 mg tadalafi l once pro re nata ; high dose, 10 mg tadalafi l once pro re nata ; FSH, follicle-stimulating hormone.…”

Section: Discussioncontrasting

confidence: 99%

“…The active forms of cortisol have been shown to have significant negative correlations with IIEF domains [8]. This finding contrasts with the results of another study that found no differences in the cortisol levels of individuals with and without ED [17]. Our findings support the hypothesis that the stress incurred by the thought of ‘obligatory coitus’ (compulsory sexual behaviour) causes sexual dysfunction in men engaging in TI.…”

Section: Discussioncontrasting

confidence: 87%

See 1 more Smart Citation

Sexual dysfunctions induced by stress of timed intercourse and medical treatment

et al. 2012

View full text Add to dashboard Cite

show abstract

Section: Discussioncontrasting

confidence: 99%

“…The active forms of cortisol have been shown to have significant negative correlations with IIEF domains [8]. This finding contrasts with the results of another study that found no differences in the cortisol levels of individuals with and without ED [17]. Our findings support the hypothesis that the stress incurred by the thought of ‘obligatory coitus’ (compulsory sexual behaviour) causes sexual dysfunction in men engaging in TI.…”

Section: Discussioncontrasting

confidence: 87%

Sexual dysfunctions induced by stress of timed intercourse and medical treatment

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Active forms of cortisol showed significant negative correlations with domains of IIEF (Kobori et al, 2009). This is in contrast with another study that indicated no differences in cortisol levels between individuals with and without ED (Derouet et al, 2002), suggesting that active forms of cortisol likely decrease sexual function. According to Kobori et al (2009), the increased level of stress could be one reason why ED occurred in patients with high levels of cortisol.…”

Section: Discussioncontrasting

confidence: 99%

Erectile Dysfunction and Extramarital Sex Induced by Timed Intercourse: A Prospective Study of 439 Men

Bak

Lyu

Seok

et al. 2012

Journal of Andrology

View full text Add to dashboard Cite

During the fertile window of a woman's menstrual cycle, the effect of impending timed intercourse (TI) on the psychological well-being and behavior of male partners has not been thoroughly investigated, despite the fact that men comprise one half of each couple endeavoring to achieve natural conception. This prospective study consisting of 439 men was conducted during a 3-year period between July 1, 2008, and June 30, 2011. Various characteristics were evaluated, including newly acquired erectile dysfunction (ED); extramarital sex (EMS); intake of soft drinks (SD); levels of hormones, such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), prolactin, and estradiol (E2); and semen parameters. A total of 188 men (42.8%) experienced ED and 47 men (10.7%) engaged in EMS. As the number of TI episodes increased, the number of men with ED and EMS and those who wanted to avoid TI also increased (all, P , .0001). All 47 men who reported EMS experienced ED with their spouses. Men who consumed SDs produced significantly smaller volumes of semen (P 5 .0363). Among the hormones investigated, the levels of LH, T, and E2 were significantly lower in men with ED (all, P , .05) whereas the level of FSH was higher in contrast to E2, which was significantly higher in men who had EMS (both, P , .01). TI imposes a great deal of stress on male partners evoking ED and, in some cases, causing these men to seek EMS. Physicians and clinicians should acknowledge the potential harmful effects of TI on men. Furthermore, both female and male partners should also be cautioned about the increased possibilities of ED and EMS as TI incidents increase.

show abstract

“…28 The serum level of total testosterone in healthy men and patients with ED do not show any difference. 29 In our study, we also observed nonsignificant association between severity of ED and total testosterone, except severe ED (IIEF%7). This finding might be explained by aging men with highlevel SHBG, as SHBG increases 0.86 nmol/l per year.…”

Section: Discussionsupporting

confidence: 48%

Association among hypogonadism, quality of life and erectile dysfunction in middle-aged and aged male in Taiwan

Hwang

Tsai³

et al. 2006

Int J Impot Res

View full text Add to dashboard Cite

The association between hypogonadism, quality of life (QoL), and erectile dysfunction (ED) among the middle-aged and aged male in Taiwan is evaluated. A total of 680 study subjects aged X40 years old were recruited from Northern (n ¼ 276), Middle (n ¼ 238), and Southern (n ¼ 202) Taiwan, respectively. ED was diagnosed by score of International Index of Erectile Function (IIEF-5). Taiwan version questionnaire for QoL includes domain 1 (physical domain), domain 2 (psychological domain), domain 3 (social relationship domain), and domain 4 (environmental domain) was used to measure QoL. Blood hormones, including FSH, LH, Prolactin, SHBG, total testosterone (TT), calculated free testosterone (cFT), and bioavailable testosterone (Bio-T), were determined. Logistic regression analysis was used to estimate crude and multivariate-adjusted odds ratio of risk factors and its 95% confidence interval. A significantly inverse association between concentration of serum cFT and Bio-T, and severity of ED was observed. Scores of QoL of Domain 1-4 were significantly decreased with the increament of severity of ED. Significant correlations were found between IIEF scores and four domains of QoL, respectively. After adjustment for age, cFT and Bio-T, study subjects with ED (IIEFp21) would have significantly high risk of low level of QoL in four domains. In conclusion, a significant association between low levels of serum calculated cFT, Bio-T, and severity of ED was found. In addition, abnormal erectile function significantly associated with low level of QoL in four domains.

show abstract

Age Dependent Secretion of LH and ACTH in Healthy Men and Patients with Erectile Dysfunction

Cited by 14 publications

References 27 publications

Sexual dysfunctions induced by stress of timed intercourse and medical treatment

Sexual dysfunctions induced by stress of timed intercourse and medical treatment

Erectile Dysfunction and Extramarital Sex Induced by Timed Intercourse: A Prospective Study of 439 Men

Association among hypogonadism, quality of life and erectile dysfunction in middle-aged and aged male in Taiwan

Contact Info

Product

Resources

About