Age‐dependent expression of abdominal symptoms in patients with <i>Yersinia enterocolitica</i> infection

Ehara, Akira; Egawa, Kiyoshi; Kuroki, Fumiko; Itakura, Osamu; Okawa, Masahito

doi:10.1046/j.1442-200x.2000.01240.x

Cited by 8 publications

(7 citation statements)

References 12 publications

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“…This confirms results from previous studies that reported differences in clinical manifestation of Y. enterocolitica infection according to age [6,18-20]. In older children and adolescents infection is often characterized by terminal ileitis and mesenteric lymphadenitis with symptoms that may resemble appendicitis [20-22]. In our study, pain in the lower right abdomen was strongly associated with hospitalization and appendectomy.…”

Section: Discussionsupporting

confidence: 92%

Clinical aspects and self-reported symptoms of sequelae of Yersinia enterocolitica infections in a population-based study, Germany 2009–2010

et al. 2013

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BackgroundFoodborne Yersinia enterocolitica infections continue to be a public health problem in many countries. Consumption of raw or undercooked pork is the main risk factor for yersiniosis in Germany. Small children are most frequently affected by yersiniosis. In older children and young adults, symptoms of disease may resemble those of appendicitis and may lead to hospitalization and potentially unnecessary appendectomies. Y. enterocolitica infections may also cause sequelae such as reactive arthritis (ReA), erythema nodosum (EN), and conjunctivitis.MethodsWe studied clinical aspects of yersiniosis, antimicrobial use, and self-reported occurrence of appendectomies, reactive arthritis, erythema nodosum and conjunctivitis. To assess post-infectious sequelae participants of a large population-based case–control study on laboratory-confirmed Y. enterocolitica infections conducted in Germany in 2009–2010 were followed for 4 weeks.ResultsDiarrhea occurred most frequently in children ≤4 years (95%); abdominal pain in the lower right quadrant was most common in children 5–14 years of age (63%). Twenty-seven per cent of patients were hospitalized, 37% were treated with antimicrobials. In 6% of yersiniosis patients ≥5 years of age, appendectomies were performed. Self-reported symptoms consistent with ReA were reported by 12% of yersiniosis patients compared to 5% in a reference group not exposed to yersiniosis. Symptoms consistent with EN were reported by 3% of yersiniosis patients compared to 0.1% in the reference group. Symptoms of conjunctivitis occurred with the same frequency in yersiniosis patients and the reference group.ConclusionsAcute Y. enterocolitica infections cause considerable burden of illness with symptoms lasting for about 10 days and hospitalizations in more than a quarter of patients. The proportion of yersiniosis patients treated with antimicrobial drugs appears to be relatively high despite guidelines recommending their use only in severe cases. Appendectomies and post-infectious complications (ReA and EN) are more frequently reported in yersiniosis patients than in the reference group suggesting that they can be attributed to infections with Y. enterocolitica. Physicians should keep recent Y. enterocolitica infection in mind in patients with symptoms resembling appendicitis as well as in patients with symptoms of unclear arthritis.

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Section: Discussionsupporting

confidence: 92%

Clinical aspects and self-reported symptoms of sequelae of Yersinia enterocolitica infections in a population-based study, Germany 2009–2010

et al. 2013

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“…Clinical presentations vary from mild enteric symptoms to more severe cases of enterocolitis with fever and bloody diarrhea. A pseudoappendicitis syndrome with terminal ileitis and mesenteric adenitis has been described, usually affecting older children [6,10].…”

Section: Discussionmentioning

confidence: 99%

“…Gastrointestinal symptoms may mimic appendicitis and even lead to appendectomy [5]. The pseudoappendicitis syndrome seems to occur predominantly in older children and adolescents and is usually characterized by terminal ileitis and mesenteric adenitis [6]. A small percentage of patients may present with true appendicitis as a complication of Yersinia infection or with features of chronic active colitis mimicking inflammatory bowel disease [7,8].…”

Section: Introductionmentioning

confidence: 99%

Yersinia enterocolitica infection mimicking surgical conditions

et al. 2006

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Yersinia enteritis may present with alarming gastrointestinal manifestations. The aim of this study was to review the cases of children admitted to a general hospital with a preliminary diagnosis of surgical nature and subsequently proven to be infected by Yersinia enterocolitica. All cases of children aged less than 14 years with stool cultures positive for Y. enterocolitica during the 12-year period January 1993 through December 2004 were analyzed. Y. enterocolitica was isolated from the stools of 71 children with gastrointestinal manifestations; 27 children were treated as outpatients and 44 were hospitalized. Six were admitted to the Pediatric Surgery Department (13.6% of the total hospitalizations and 8.4% of all Y. enterocolitica cases). Four of the Pediatric Surgery patients presented with abdominal pain and right lower quadrant tenderness. The preliminary diagnosis of appendicitis was excluded during hospitalization and none of them underwent appendectomy. The other two children were admitted for vomiting initially attributed to a preceding head injury and for diarrhea and a perianal abscess. Two children were given antibiotics and all had an excellent outcome. Y. enterocolitica enteritis manifestations can infrequently mimic appendicitis or other surgical conditions but should remain in the differential diagnosis of children presenting with an acute abdomen.

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“…Yersiniosis had a global prevalence and is a reportable disease in some countries, such as Denmark, Norway, and 38 states of USA [59,60]. According to PCR detection, Africa and Western Pacific [3,9,18,23,27,37] had the most, and the Americas [20, 30-32, 41, 51, 52, 55] had the least prevalence of Y. enterocolitica. In the present study, the highest prevalence of Y. enterocolitica in culture and PCR method was in Madagascar (16.56%).…”

Section: Discussionmentioning

confidence: 99%

Global Prevalence of Yersinia enterocolitica in Cases of Gastroenteritis: A Systematic Review and Meta-Analysis

Riahi

Ahmadi

Zeinali

2021

International Journal of Microbiology

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The prevalence of Yersinia enterocolitica in gastroenteritis is often underestimated. It relates considerably to morbidity and medical expenses around the world. Understanding the cause of gastroenteritis leads to making the appropriate treatment decisions. We systematically searched PubMed, Science Direct, Embase, and Scopus to identify all published studies between Jan. 1, 2000, and Dec. 31, 2019, to assess the prevalence of Y. enterocolitica in gastroenteritis patients. A total of 5039 articles were identified that lead to the extraction of data from 47 of them. The pooled prevalence of Y. enterocolitica in cases of gastroenteritis was estimated as 1.97% (1.32–2.74%) in the culture method and 2.41% (1.07–4.22%) in the molecular method. Among the biotypes of Y. enterocolitica, 1A (62.48%) and 1B (2.14%) had the most and least prevalence, respectively. Serotype O3 Y. enterocolitica with 39.46% had the highest and O5,27 with 0.0% had the least prevalence in gastroenteritis cases. In conclusion, the findings of this systematic review show that Y. enterocolitica is prevalent in gastroenteritis in all age groups. Serotypes O3 and O9 of Y. enterocolitica had the highest prevalence and O5,27 had the least prevalence in diarrheal patients. The prevalence of Y. enterocolitica was similar in both gender and different seasons. It should be noted that to determine the role of the organism, more studies are needed especially in food-borne diseases.

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Age‐dependent expression of abdominal symptoms in patients with Yersinia enterocolitica infection

Abstract: In Yersinia enterocolitica infections, younger children are predisposed to diarrhea and older children are predisposed to abdominal pain.

Cited by 8 publications

References 12 publications

Clinical aspects and self-reported symptoms of sequelae of Yersinia enterocolitica infections in a population-based study, Germany 2009–2010

Clinical aspects and self-reported symptoms of sequelae of Yersinia enterocolitica infections in a population-based study, Germany 2009–2010

Yersinia enterocolitica infection mimicking surgical conditions

Global Prevalence of Yersinia enterocolitica in Cases of Gastroenteritis: A Systematic Review and Meta-Analysis

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