Age Changes in the Thymus- A Histological and Morphological Study

Sivan, Sheela; Viswasom, Angela A.; Krishnan, Binu

doi:10.14260/jemds/615

Cited by 1 publication

(1 citation statement)

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“…According to research by (Sivan et al, 2013), who also demonstrated that the stromal elements of mesodermal origin are capillaries, septa and perivascular spaces and single invasive cells.…”

Section: Discussionmentioning

confidence: 99%

Study of anatomical, histological and cytological characteristics of the thymus of lambs

Rahmoun¹,

Lieshchova²,

Chaanbi³

et al. 2020

TAVM

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Thymus of lambs of the Ouled-Djellal breed from eastern Algeria, aged one to 10 months, were used to study the anatomical, histological and cytological characteristics of these organs. Modern techniques have been used to demonstrate the morphometric parameters and masses of the thymus at different ages, a regression of the morphometric and mass indexes has been visualized according to the age of the lambs. Staining techniques with Hematoxylin and eosin revealed the normal structure of the thymus with its tissue components. The thymus is bilobed. The lobe is surrounded by a thin capsule and subdivided into lobules separated by septae, the cortical and medullary areas were clearly visible, the interlobular blood vessels enter the lobule in all its aspects to continue its way as interlobular blood vessels. From the changes observed in the involution of the thymus according to the age of the animals which occur relatively late, the percentage of the surface found for the capsule was very variable, which increases from the first to the tenth month, the demarcation of the cortex and the medulla beginning during the second month of age of the animal. The interlobular connective tissue (ILC) presents sums, the maximum of which was found in the fourth month of age of the animal, while the minimum was found in the thymus of ninth month lambs Concerning the Hassal corpuscles, their sums are in high extension until the tenth month, rich in T lymphocytes, whose use of immunohistochemistry, the anti-CD 157+ antibody allowed us to visualize to locate them clearly, which invade and form most of the thymus cortex. In conclusion, the significant changes in thymus development in sheep of the Ouled-Djellal breed are similar to those of other species.

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Section: Discussionmentioning

confidence: 99%