Age at drinking onset, age at first intoxication, and delay to first intoxication: Assessing the concurrent validity of measures of drinking initiation with alcohol use and related problems

Morean, Meghan E.; L’Insalata, Alexa; Butler, Ellyn R.; McKee, Avalon; Krishnan‐Sarin, Suchitra

doi:10.1016/j.addbeh.2017.12.017

Cited by 29 publications

(34 citation statements)

References 29 publications

(34 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Initiation of alcohol use is commonly reported during early (11-15 years of age) adolescence (Faden, 2006;Masten et al, 2009;Morean et al, 2018), and this early initiation is frequently associated with the development of alcohol abuse/dependence later in life (Kuntsche et al, 2016). Several researchers have reported that adolescents who begin drinking at or before the age of 14 are at an elevated risk of becoming alcohol-dependent compared to those who initiate alcohol use at the age of 19 or later (DeWit et al, 2000;Ehlers et al, 2006;Dawson et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

“…Several researchers have reported that adolescents who begin drinking at or before the age of 14 are at an elevated risk of becoming alcohol-dependent compared to those who initiate alcohol use at the age of 19 or later (DeWit et al, 2000;Ehlers et al, 2006;Dawson et al, 2008). Likewise, a fast progression from first drink to the first intoxication is a strong predictor and indicator of binge and high-intensity drinking among adolescents (Morean et al, 2014(Morean et al, , 2018Kuntsche et al, 2016;Patrick et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Adolescent Ethanol Exposure: Anxiety-Like Behavioral Alterations, Ethanol Intake, and Sensitivity

Towner

2020

Front. Behav. Neurosci.

View full text Add to dashboard Cite

Adolescence is a developmental period associated with rapid age-specific physiological, neural, and hormonal changes. Behaviorally, human adolescents are characterized by age-typical increases in novelty-seeking and risk-taking, including the frequent initiation of alcohol and drug use. Alcohol use typically begins during early adolescence, and older adolescents often report high levels of alcohol consumption, commonly referred to as high-intensity drinking. Early-onset and heavy drinking during adolescence are associated with an increased risk of developing alcohol use disorders later in life. Yet, long-term behavioral consequences of adolescent alcohol use that might contribute to excessive drinking in adulthood are still not well understood. Recent animal research, however, using different exposure regimens and routes of ethanol administration, has made substantial progress in identifying the consequences of adolescent ethanol exposure that last into adulthood. Alterations associated with adolescent ethanol exposure include increases in anxiety-like behavior, impulsivity, risk-taking, and ethanol intake, although the observed alterations differ as a function of exposure regimens and routes of ethanol administration. Rodent studies have also shown that adolescent ethanol exposure produces alterations in sensitivity to ethanol, with these alterations reminiscent of adolescent-typical ethanol responsiveness. The goal of this mini-review article is to summarize the current state of animal research, focusing on the long-term consequences related to adolescent ethanol exposure, with a special emphasis on the behavioral alterations and changes to ethanol sensitivity that can foster high levels of drinking in adulthood.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Adolescent Ethanol Exposure: Anxiety-Like Behavioral Alterations, Ethanol Intake, and Sensitivity

Towner

2020

Front. Behav. Neurosci.

View full text Add to dashboard Cite

show abstract

“… Dawson, Goldstein, Chou, Ruan, & Grant, 2008 ; Henry et al, 2011 ; Hingson, Heeren, & Winter, 2006 ; Hingson & Zha, 2009 ; Marino & Fromme, 2016 ; Patte, Qian, & Leatherdale, 2017 ; Warner & White, 2003 ; Warner, White, & Johnson, 2007 ). More recently, delay to first intoxication (i.e., the lag time between AO and AI) has been identified as an independent alcohol-related risk factor ( Morean et al, 2014 ; Morean, Corbin, & Fromme, 2012 ; Morean, L'Insalata, Butler, McKee, & Krishnan-Sarin, 2018 ). Of note, delay to intoxication (AI – AO) is conceptualized as a more informative way of understanding early intoxication, as it deconstructs intoxication into two independent constructs: age of onset and delay to first intoxication.…”

Section: Introductionmentioning

confidence: 99%

“…In conjunction, AO and delay account for more variance in drinking outcomes in samples of high school and college students than either AO or AI alone ( Morean et al, 2012 ; Morean et al, 2014 ). Furthermore, recent research suggests that using concrete terminology to assess AO (i.e., the age at which an individual first consumes at least 1 standard drink) and AI (i.e., the age at which an individual first engages in a binge drinking episode) outperforms using subjective terminology (e.g., assessing first intoxication using first subjective “drunk”) when predicting alcohol-related outcomes ( Morean et al, 2018 ). Although there is mounting evidence that both an early AO and a short delay confer alcohol-related risk, there has been no research examining risk factors for a short delay to first intoxication itself.…”

Section: Introductionmentioning

confidence: 99%

Predictors of quickly progressing from initiating alcohol use to engaging in binge drinking among adolescents

Morean

Peterson

L’Insalata

2019

Addictive Behaviors Reports

Self Cite

View full text Add to dashboard Cite

Background A short delay to first intoxication confers alcohol-related risk, but risk factors for a short delay have yet to be examined. Methods 230 high school students (55.7% male; age 16.52 [1.19] years; 70.9% White) were surveyed about alcohol use. We examined whether sex, race, parental history of alcohol problems, age of onset, type of alcohol consumed, drinking company, and subjective response to alcohol were associated with 1) delay to first binge episode and 2) binge drinking status (i.e., never bingers, individuals who binge drank on their first drinking occasion, and individuals who binge drank at a later date). Finally, we examined whether first-occasion bingers reported heavier drinking and alcohol-related problems than later-occasion and never bingers. Results Overall, a shorter delay was associated with being male an older age of onset, and, during one's first drinking experience, consuming liquor, drinking with friends or alone, and experiencing high arousal negative alcohol effects. First-occasion bingers were more likely to be male, consume liquor, and experience stronger high arousal positive and negative alcohol effects than never bingers and to have a later age of onset, experience stronger high arousal negative, and weaker low arousal negative alcohol effects than later-occasion bingers. First-occasion bingers also reported heavier current drinking and more alcohol-related problems. Conclusions Characteristics of underage drinkers that confer risk for a shorter delay and first-occasion binging may provide fruitful targets for intervention, as efforts to delay binge drinking may mitigate alcohol-related risk associated with underage alcohol use.

show abstract

“…Nonetheless, aggregated data have the advantage of not being affected by self-selection bias, a common limitation of longitudinal studies. Furthermore, some evidence signals that different ED measures (such as first sip, first drunkenness, or initiation of regular drinking) might yield different results (Morean et al, 2018). It has also been suggested (Maggs et al, 2019) that there might be differences in whether drinking initiation occurs during early adolescence or during childhood (i.e., before 11 years of age), and we did not consider those factors.…”

Section: Relationships Between Ed and Dependence For All Countries Anmentioning

confidence: 95%

The Association Between Early Drinking and Dependence Varies by Drinking Context

Conde

Peltzer

Gimenez

et al. 2020

Front. Behav. Neurosci.

View full text Add to dashboard Cite

Evidence regarding the association between early drinking (ED) and later dependence is controversial. It has been alternately hypothesized that ED either plays a causal role in the development of dependence or that it is an early marker of increased psychosocial vulnerabilities. Despite a clear rationale for delaying youth consumption, it is important to discern this relationship. However, most epidemiological evidence comes from individual studies and high-income countries. If there is a causal link between ED and dependence, an association at the aggregate level would be expected. Furthermore, if the link is due to biological mechanisms, the association should be rather invariable regardless of the drinking context, while if the association is due to psychosocial factors, a wider variability is to be expected. We explored whether the association between ED and dependence varied across countries clustered by their shared contextual drinking characteristics. We used data from 169 countries from the Global Information System on Alcohol and Health of the World Health Organization: ED, alcohol dependence, heavy episodic drinking (HED), actual drinkers, and alcohol policy. To cluster countries by their shared drinking characteristics (prevalences of HED and actual drinkers, and alcohol policy), we used, sequentially, two multivariate data reduction techniques: a multiple correspondence analysis (MCA) and a hierarchic classification. To estimate the association between ED and alcohol dependence, beta regressions were performed, and then adjusted by country income-level and repeated by gender. The results indicated four country clusters: primarily abstainers (class 1), low drinking countries (class 2), high drinking countries (class 3), and very high drinking countries (class 4). Positive relationships between ED and alcohol dependence were found for all the countries in the world and for those in classes 1 and 2. No significant relationships were found for class 3 or class 4. These results were similar for males, but not for females, where no significant relationships were found after adjusting for income level. The association between ED and dependence varies according to the drinking context. Our findings either suggest that the ED-dependence association may be due to individual or environmental vulnerabilities that promote consumption outside cultural norms or that, if there is a causal link between ED and dependence, it is strongly moderated by psychosocial characteristics.

show abstract

Age at drinking onset, age at first intoxication, and delay to first intoxication: Assessing the concurrent validity of measures of drinking initiation with alcohol use and related problems

Abstract: Clearly defining AO and AI using objective definitions that reflect specific amounts of alcohol (e.g., first sip; first standard drink; first binge) appears to outperform subjective definitions of alcohol use (e.g., first drunk).

Cited by 29 publications

References 29 publications

Adolescent Ethanol Exposure: Anxiety-Like Behavioral Alterations, Ethanol Intake, and Sensitivity

Adolescent Ethanol Exposure: Anxiety-Like Behavioral Alterations, Ethanol Intake, and Sensitivity

Predictors of quickly progressing from initiating alcohol use to engaging in binge drinking among adolescents

The Association Between Early Drinking and Dependence Varies by Drinking Context

Contact Info

Product

Resources

About