Age and gender-specific distribution of metabolic syndrome components in East China: role of hypertriglyceridemia in the SPECT-China study

Abstract

BackgroundChinese population are experiencing remarkably changes of economic and cultural environments. The present study was to examine the prevalence of metabolic syndrome (MetS) by age between genders and to investigate the current characteristics of MetS and its components in China.MethodsSPECT-China is a population-based cross-sectional survey on Chinese adults aged ≥18 years in East China. A total of 10,441 Chinese residents participated in anthropometric and laboratory measurements. Of these, 9969 subjects (females, 5868) were eligible for the data analysis reported here. Estimates of the prevalence of MetS and its components were calculated. Presence of MetS was defined based on the IDF/AHA harmonized criteria. MetS z-score was calculated to evaluate the degree of total metabolic disorder.ResultsThe age-standardized prevalence of the metabolic syndrome was 22.0% (21.9% in men and 22.0% in women). Unlike the continuous MetS rise with age in females, the MetS prevalence in males remained stable among 46–55, 56–65 and > 65 yrs. age groups (31.2%, 31.4%, 32.5%, p = 0.538). In the five components of MetS, contrary to the elevated BP and BG disorders, the frequency of TG disorders decreased with age in males (46.6%(46–55 yrs), 37.2% (56–65 yrs), 27.7%(> 65 yrs), p < 0.001). Multivariable logistic regression showed that in males, more TG disorders were associated with higher BMI, higher educational level and current nonsmoker. In the MetS subjects, the 3-factor combinations which included TG disorders decreased with age in both genders. The whole metabolic profile became better in older male MetS subjects, which was opposite to the female.ConclusionOur results showed a distinct age-related prevalence of MetS between genders in dramatically changed China, in which the TG disorders played an important role. More targeted measures need to be taken to meet the serious challenges of metabolic diseases.Trial registrationChiCTR-ECS-14005052, Survey on Prevalence in East China for Metabolic Diseases and Risk Factors (SPECT-China).Electronic supplementary materialThe online version of this article (10.1186/s12944-018-0747-z) contains supplementary material, which is available to authorized users.

Urbanization-gradient-, gender- and age-specific prevalence of metabolic syndrome abnormal components and their accumulation in adults in Burkina Faso: analysis of the first national data

“…In men as in women, the prevalence of high FBG increased with either urbanization gradient or age ( Figures 3C, 4C & Supplemental Table) The increase in glycemia with urbanization gradient (prevalence of diabetes was 0.8%, 3% and 6% for rural, rural-to-urban migrants, and urban Peruvians) (40) has been identi ed. The age-speci c change in prevalence of elevated FBG in both sexes ( Figure 4C & Supplemental Table) was closely to its spectrum reported among for both sexes in the age-groups of 18-45, 46-55 and 56-65 years in China (41) . Moreover, since high FBG a prediabetes state reached 13.0/10.3% in men/women of Q4, and 11.0/14.2% in those aged 55-64y (Supplemental Table) the epidemiological surveillance is required.…”

“…China (41) . The overall prevalence of high BP (SBP/DBP≥140/90 mmHg or medication for hypertension) was low in Burkina Faso (18%) (24) but in Q4 and 55-64 age range, the respective prevalence of elevated BP in men/women reached 49.1/30.3% and 48.2/51.6%.…”

Comparative study on prevalence of metabolic syndrome based on three criteria among adults in Zhejiang province, China: an observational study

“…These results were similar to those reported in an epidemiological survey in east China, in which TG disorder was found to be a significant risk factor. 32 Previous data reported that obesity, dyslipidaemia and increased FPG were prevalent components of MetS among Han Chinese using CDS 2013. 42 A national survey in Indonesia reported decreased HDL-C and hypertension as the two most prevalent risk factors for MetS.…”

Prevalence of Metabolic Syndrome and Its Components in Adult Women

“…대사증후군 유병률은 연구에 따라 다양하게 보고하고 있으며, 성별, 나이, 인종, 지역 등에 따라 차이가 있는 것으로 보고하고 있는 데 [7], 대체적으로 나이가 증가할수록 대사증후군 유병률이 증가하 는 것으로 보고하고 있다 [3,8]. 또한 대사증후군 유병률은 계속적으 로 증가하는 추세를 보이고 있으며 [8,9], 발병연령에 있어 성인뿐 아 니라 아동 및 청소년의 대사증후군 유병률도 증가하고 있어 문제점 으로 제기되고 있다 [2].…”

“…우리나라의 경우도 생활습관의 변화, 영양 과다섭취 및 운동 부족 등으로 인해 대사증후군 유병률이 증가하 고 있으며 [10], 앞으로도 점차 증가할 것으로 추정된다 [11]. 특히 여성 의 경우 연령이 증가할수록 남성에 비해 대사증후군 유병률이 높 고 이로 인한 심혈관계 질환에 노출되는 위험도도 높은 것으로 보 고하고 있다 [3,7,12]. 또한 폐경 이후에는 대사증후군의 유병률이 더 높아지면서 심혈관계 질환 발병 위험도도 더욱 높아지는 것으로 보 고하고 있는데 [13,14], 이는 여성의 주요 사망 원인으로 남성보다 더 높은 비율을 보이고 있다 [15].…”