After 30 years … the future of hydroxyacids

Green, Barbara

doi:10.1111/j.1473-2165.2005.00159.x

Cited by 17 publications

(25 citation statements)

References 6 publications

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“…Finally, α-hydroxy acids (αHAs) have been widely used in cosmetic products to improve skin damage caused by UV light, having been successfully shown to decrease roughness, solar keratosis, and excessive pigmentation, as well as to increase collagen levels and elastic-fibre density [25] [26] [27]. Products containing HAs generally improve exfoliation and moisturization [28].…”

Section: Discussionmentioning

confidence: 99%

Improving Skin Aging, Skin Hydration and Sensitive Skin with Four Specific Skin Care Products: Results from a Single-Centre, Observational, Prospective Study

Piccioni¹,

García-Rodrigo²,

Pellegrini³

et al. 2017

JCDSA

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In this study, we assessed the efficacy and safety of four skin care products indicated for skin hydration (Aqua Therapy  and Perfecta ) and are formulated with a specific combination of active compounds (Dermo28  ). Evaluation of sebum secretion, hydration and pH of the skin (all groups), wrinkle severity (Unica Resurfacing Therapy  ) and erythema (Comfort Therapy  ) was performed at baseline and after 4 weeks of treatment. A significant increase in hydration was recorded in subjects with dry skin receiving Aqua Therapy  for facial hydration and Perfecta  for body hydration, respectively (p < 0.001 for both). A significant decrease in the modified Fitzpatrick wrinkle scale (p = 0.006) and an increase in sebum secretion and hydration (p = 0.013 and p < 0.001, respectively) were observed in the Unica Resurfacing Therapy  group. In subjects with sensitive skin (Comfort Therapy  ), a decrease in erythema (p = 0.012), an increase in sebum secretion (p = 0.001) and hydration (p < 0.001), and a reduction in pH (p = 0.005) were detected at the end of treatment. Only one patient reported a minor adverse event. This specific combination of active ingredients was clinically effective and safe, and contributed to skin surface hydrolipidic film regeneration, improvement of wrinkle depth and reduction of redness.

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Section: Discussionmentioning

confidence: 99%

Improving Skin Aging, Skin Hydration and Sensitive Skin with Four Specific Skin Care Products: Results from a Single-Centre, Observational, Prospective Study

Piccioni¹,

García-Rodrigo²,

Pellegrini³

et al. 2017

JCDSA

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“…These improvements have been measured as decreases in roughness, discoloration, solar keratoses, overall pigmentation, and also as increased density of collagen and improved quality of elastic fibers [2]. The antiaging effects of HAs have become a prominent factor in cosmetic dermatology, leading to proliferation of HA-containing cosmetic products and skin care systems [3]. …”

Section: Introductionmentioning

confidence: 99%

The effects of topically applied glycolic acid and salicylic acid on ultraviolet radiation-induced erythema, DNA damage and sunburn cell formation in human skin

Kornhauser

Wei

Yamaguchi

et al. 2009

Journal of Dermatological Science

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Background-α-Hydroxy acids (αHA) are reported to reduce signs of aging in the skin and are widely used cosmetic ingredients. Several studies suggest that αHA can increase the sensitivity of skin to ultraviolet radiation. More recently, β-hydroxy acids (βHA), or combinations of αHA and βHA have also been incorporated into antiaging skin care products. Concerns have also arisen about increased sensitivity to ultraviolet radiation following use of skin care products containing β-HA.

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“…A negative side effect of AHAs may be a sensation of stinging or burning immediately after application, particularly on people with sensitive skin. New more lipophilic AHAs will be utilized more in the future, especially when targeting oily skins (3). …”

mentioning

confidence: 99%

“…In the other hands, they are lipid-soluble in contrast to water solubility of AHAs. This structure allows them to penetrate into the skin through sebaceous follicles, making it appropriate for patients with oily skin and open comedones (3). In addition to prove anti-inflammatory effect of BHAs (e.g.…”

mentioning

confidence: 99%