“…These include the antimetabolite methotrexate (75,76), the cytostatic active antibiotics adriamycin and daunomycin (77) and bleomycin (78), the organochlorine insecticides aldrin and dieldrin (79), the irreversible cholinesterase blocker parathion (80), the carcinogen aflatoxin 81 (81), the toxins of the dangerous toadstool Amanita phalloides, amanitins (42,82), the tuberculostatic drug isoniacid (83), the cardiovascular drugs 9,1O-dihydroergotamine (84), saralasin (85) and theophyllin (86), the peptide hormones motilin (87) and substance P (88), the anti-ulcer drug carbenoxolone (73), the polyamine spermine (36), several prostaglandins and prostaglandin metabolites (89,90,91,92), thromboxane 82 (93), the opiate antagonist naloxone (94), the benzodiazepine chlordiazepoxide (95), colchicine (96,97), a drug used in gouty arthritis, the pineal hormone melatonin (98,99) and (j-3,4-dimethoxyphenethylamine (100), a compound possibly associated with certain mental diseases.…”