Aerobic training increases skin perfusion by a nitric oxide mechanism in type 2 diabetes

Colberg, S R

doi:10.2147/dmso.s12136

Cited by 4 publications

(2 citation statements)

References 22 publications

(39 reference statements)

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“…21,22,26,29 It is difficult to generalize the RCT findings due to The underlying mechanism of how physical activity delays arteriosclerosis is still unclear and the following pathways are proposed: (i) physical activity improves blood glucose, blood pressure, and blood lipids, which are well-known risk factors of arterial stiffness, 40 (ii) physical activity improves body composition, leading to fat mass reduction, which in turn inhibits the secretion of various inflammatory mediators (eg, interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α)) that are known to cause atherosclerosis, 41,42 and (iii) physical activity improves blood circulation and releases vasodilators (eg, nitric oxide) to improve blood and oxygen supply to the tissues and protects vascular endothelial cells, which in turn delays arteriosclerosis. [43][44][45]…”

Section: Discussionmentioning

confidence: 99%

Association Between Physical Activity and Arterial Stiffness in Patients with Type 2 Diabetes in Ningbo, China: A Cross-Sectional Study

Li,

Chattopadhyay,

Chen

et al. 2023

DMSO

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The study aimed to investigate the association between physical activity and arterial stiffness in patients with type 2 diabetes mellitus (T2DM) in Ningbo, China. Methods: A cross-sectional study was conducted using the Metabolic Management Center (MMC) dataset of The First Affiliated Hospital of Ningbo University from 1st March 2018 to 28th February 2023. 4444 adults with T2DM were included in the study. Physical activity was assessed using the International Physical Activity Questionnaire (IPAQ)-Short and was categorized into high, moderate, and low. Arterial stiffness was defined as brachial-ankle pulse wave velocity (baPWV) ≥1800cm/s or common carotid artery intima-media thickness (CCA IMT) ≥1mm. Multiple logistic regression analyses were performed to identify the association between physical activity and arterial stiffness. Results: 6.5%, 47.0%, and 46.5% of patients with T2DM had high, moderate, and low physical activity, respectively. 18.8% and 17.5% of patients had arterial stiffness based on baPWV and CCA IMT, respectively. The odds of arterial stiffness (based on baPWV) were lower in patients having moderate to high physical activity (OR 0.82, 95% CI 0.68 to 0.98 and OR 0.58, 95% CI 0.39 to 0.87, respectively). The odds of arterial stiffness (based on CCA IMT) were found to be lower in patients having high physical activity (OR 0.49, 95% CI 0.33 to 0.74). Conclusion: Higher physical activity was found to be associated with lower arterial stiffness in patients with T2DM in Ningbo, China. This was a cross-sectional study, and there is a need to conduct longitudinal studies on this topic.

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Section: Discussionmentioning

confidence: 99%

Association Between Physical Activity and Arterial Stiffness in Patients with Type 2 Diabetes in Ningbo, China: A Cross-Sectional Study

Li,

Chattopadhyay,

Chen

et al. 2023

DMSO

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“…As already mentioned, these factors are particularly important for postprandial glycemia, as it is known that insulin secretion after the meal will result in deficit [17,54]. Especially in athletes with T2D, it is certainly advisable to undertake a low-calorie diet to prevent weight gain according to the physical activity level, also considering the significant role of visceral fat in the pathogenesis of diabetes and related complications [55]. This objective must be pursued through a modest reduction of the daily caloric intake, equal to about 300-500 Kcal depending on the sport practiced [56].…”

Section: Nutritional Therapy and T2dmentioning

confidence: 99%

Nutritional Therapy for Athletes with Diabetes

Cannata

Vadalà

Ambrosio

et al. 2020

JFMK

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Diabetes is a worldwide disease also affecting the sports field. The two main forms of diabetes, namely type 1 diabetes (T1D) and type 2 diabetes (T2D), differ in both their pathological and pharmacological characteristics and thus require a distinct nutritional treatment. Diet plays an important role in the management of athletes with diabetes and is crucial to achieving their best performance. This review aims to investigate the objectives of nutritional therapy before, during and after training, in order to improve the best composition of macronutrients during meals. In this review, we provide a brief overview of recent studies about nutritional approaches to people with diabetes for performance optimization and for the control of diabetes-related complications. Thereafter, we discuss the differences between macronutrients and dietary intake before, during and after training. It can be concluded that each sport has particular characteristics in terms of endurance and power, hence demanding a specific energy expenditure and consequent nutritional adjustments. Therefore, the management of athletes with diabetes must be personalized and supported by medical professionals, including a diabetologist, physiologist and a nutritionist.

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Endurance, interval sprint, and resistance exercise training: impact on microvascular dysfunction in type 2 diabetes

Olver

Laughlin

2016

American Journal of Physiology-Heart and Circulatory Physiology

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Aerobic training increases skin perfusion by a nitric oxide mechanism in type 2 diabetes

Cited by 4 publications

References 22 publications

Association Between Physical Activity and Arterial Stiffness in Patients with Type 2 Diabetes in Ningbo, China: A Cross-Sectional Study

Association Between Physical Activity and Arterial Stiffness in Patients with Type 2 Diabetes in Ningbo, China: A Cross-Sectional Study

Nutritional Therapy for Athletes with Diabetes

Endurance, interval sprint, and resistance exercise training: impact on microvascular dysfunction in type 2 diabetes

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