Aerobic exercise training programmes for improving physical and psychosocial health in adults with Down syndrome

Andriolo, Régis B; Dib, Regina El; Ramos, Luis; Atallah, ��lvaro N; Silva, Edina MK da

doi:10.1002/14651858.cd005176.pub2

Cited by 16 publications

(12 citation statements)

References 72 publications

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“…Finally, no sport-related injuries were reported during the whole experience that may indicate not only the effectiveness but also the safety of our 12week program based on aerobic exercise at moderate intensity for individuals with Down syndrome. This is of particular interest because injuries and discomfort may lead to participants to interrupt their program (Andriolo et al, 2005). Another observation one can make when reviewing the literature is that our sample size (n 5 31) was similar to the highest ones reported in previous studies in individuals with Down syndrome (Pastore et al, 2003;Aguiar et al, 2008).…”

Section: Discussionsupporting

confidence: 54%

Aerobic training at moderate intensity reduced protein oxidation in adolescents with Down syndrome

Ordóñez

Rosety

et al. 2012

Scandinavian Med Sci Sports

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Individuals with Down syndrome have been generally described as having high levels of oxidative stress, which have been associated to an increased morbidity. Fortunately, recent studies have reported that aerobic training may upregulate antioxidant defence system both in general population and individuals with trisomy 21. Accordingly, the present study was conducted to ascertain the effectiveness of aerobic training in reducing protein oxidation. To achieve this goal, 31 adolescents with Down syndrome performed a 12-week training program on a treadmill with 3 days/week, consisting of warm-up (15 min), main part (20-35 min) at a work intensity of 60-75% of peak heart rate (HR(max) =194.5-[0.56 age]) and cool-down (10 min). A control group included seven age-, sex- and BMI-matched adolescents with trisomy 21 that did not perform any training program. Plasma carbonyl content was determined by means of a slightly modified Levine method. Pre- and post-training carbonyl contents were 1.98 ± 0.2 [95% confidence intervals (95% CI): 1.94-2.02] nmol/mg protein and 1.16 ± 0.1 (95% CI: 1.14-1.18) nmol/mg protein, respectively. When compared with baseline values, it was decreased significantly (1.98 ± 0.2 vs 1.16 ± 0.1; P<0.001). It was concluded that 12-week exercise program significantly reduced protein oxidation in adolescents with Down syndrome. Further long-term follow-up studies are required to determine whether correction of this oxidant imbalance improves clinical outcomes of individuals with trisomy 21.

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Section: Discussionsupporting

confidence: 54%

Aerobic training at moderate intensity reduced protein oxidation in adolescents with Down syndrome

Ordóñez

Rosety

et al. 2012

Scandinavian Med Sci Sports

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“…Moreover, IT seems to be a more effective way compared with less intense continuous types of exercise to reduce body weight in adolescents and adults in the general population (Gutin et al 2005;Tjønna et al 2008;Trapp et al 2008). Most studies using CAT showed no improvement in body or fat mass in a DS population 328 (Varela et al 2001;Tsimaras et al 2003;Andriolo et al 2011), which was confirmed in a review (Dodd & Shields 2005). Another review by González-Agüero et al (2010) stipulated that perhaps the training intensity and/or volume did not provide a sufficient stimulus for loss in body weight in a DS population.…”

Section: Discussionmentioning

confidence: 91%

Effect of continuous aerobic vs. interval training on selected anthropometrical, physiological and functional parameters of adults with Down syndrome

Boer

Moss

2016

J intellect Disabil Res

143

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“…The limited reviews that study the efficacy of PT (Shields & Dodd 2004;Dodd & Shields 2005;Andriolo et al 2010;Hardee & Fetters 2017;Bertapelli et al 2016;Sugimoto et al 2016) in this population focus on a specific type of intervention. Likewise, there are no known clinical practice guidelines that support the PT interventions in this population.…”

Section: Introductionmentioning

confidence: 99%

Physical therapy in Down syndrome: systematic review and meta‐analysis

Ruiz-González

Lucena-Antón

Salazar

et al. 2019

J intellect Disabil Res

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Background Down syndrome is the most common chromosomal abnormality, with a worldwide incidence of around 0.1% in live births. It is related to several conditions in which the physical therapy could take action‐preventing co‐morbidities. This study aims to evaluate the effectiveness of physical therapy in Down syndrome, to know and compare the effectiveness of different physical therapy interventions in this population. Methods A systematic review and a meta‐analysis of randomised controlled trials were conducted. The search was performed during June 2018 in the following databases: PubMed, Web of Science, Physiotherapy Evidence Database and Scopus. The studies were selected using predefined inclusion and exclusion criteria. The Physiotherapy Evidence Database scale evaluated the quality of the methods used in the studies. Subsequently, the data were extracted, and statistical analysis was performed when possible. Results A total of 27 articles were included, of which nine contributed information to the meta‐analysis. Statistical analysis showed favourable results for the strength of upper and lower limbs [standardised mean difference (SMD) = 1.46; 95% confidence interval (CI): (0.77–2.15); and SMD = 2.04; 95% CI: (1.07–3.01)] and mediolateral oscillations of balance [SMD = −3.30; 95% CI: (−5.34 to −1.26)]. Conclusions The results show the potential benefit of certain types of physical therapy interventions, specifically in strength and balance, in people with Down syndrome. There are still many aspects to clarify and new lines of research.

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Aerobic exercise training programmes for improving physical and psychosocial health in adults with Down syndrome

Cited by 16 publications

References 72 publications

Aerobic training at moderate intensity reduced protein oxidation in adolescents with Down syndrome

Aerobic training at moderate intensity reduced protein oxidation in adolescents with Down syndrome

Effect of continuous aerobic vs. interval training on selected anthropometrical, physiological and functional parameters of adults with Down syndrome

Physical therapy in Down syndrome: systematic review and meta‐analysis

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