Aerobic exercise: effects on parameters related to fatigue, dyspnea, weight and body composition in HIV-infected adults

Smith, Barbara A.; Neidig, Judith L.; Nickel, Jennie T.; Mitchell, G. Lynn; Para, Michael F.; Fass, Robert J.

doi:10.1097/00002030-200104130-00004

Cited by 130 publications

(177 citation statements)

References 25 publications

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“…After screening titles and application of the eligibility criteria, 21 studies (Baigis et al, 2002;Cade et al, 2003;Cade et al, 2013;Cutrono et al, 2015;Dolan et al, 2006;Ezema et al, 2014;Hand et al, 2008;Jaggers et al, 2014;MacArthur et al, 1993;Mangona et al, 2015;Mapstone et al, 2014;Mutimura et al, 2008;Neto et al, 2016;Oursler et al, 2009;Perna et al, 1999;Ramírez-Marrero et al, 2014;Raso et al, 2013;Smith et al, 2001;Sullivan et al, 2014;Terry et al, 2006;Thoni et al, 2002) were eligible for inclusion in the meta-analysis. (n=31) and sub-maximal (n=5) exercise tests.…”

Section: Search Results and Flow Of Studies Through The Reviewmentioning

confidence: 99%

Cardiorespiratory fitness levels and moderators in people with HIV: A systematic review and meta-analysis

Vancampfort

Mugisha

Rosenbaum

et al. 2016

Preventive Medicine

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Cardiorespiratory fitness (CRF) is a modifiable risk factor for cardiovascular disease and premature mortality. CRF levels and moderators among people living with HIV (PLWH) are unknown. The aim of the current meta-analysis was to (1) determine mean CRF in PLWH and compare levels with age-and gender-matched healthy controls (HCs), (2) explore moderators of CRF,3and (4) explore moderators of CRF outcomes following physical activity (PA) interventions. Major electronic databases were searched systematically for articles reporting CRF expressed as maximum or peak oxygen uptake (ml/min/kg) in PLWH. A random effects meta-analysis calculating the pooled mean CRF including subgroup-and meta-regression analyses was undertaken. Across 21 eligible studies, the CRF level was 26.4 ml/kg/min (95%CI=24.6 to 28.1) (n=1,010; mean age =41years). There were insufficient data to compare CRF levels with HCs. A higher body mass index (β=-0.99, 95%CI=-1.93 to -0.06, P=0.04), older age (β=-0.31, 95%CI=-0.58 to -0.04, P=0.02) and the presence of lipodystrophy (β=-4.63, 95%CI=-7.88 to -1.39, P=0.005) were significant moderators of lower CRF levels. Higher CD4+ counts (β=0.004, 95%CI=0.0007 to 0.007, P=0.016), supervised interventions (P<0.001) and interventions with a lower frequency of weekly sessions (2 or 3 versus 4 times) (P<0.001) predicted a better CRFoutcome following PA. CRF levels of PLWH are among the lowest in comparison to other vulnerable populations. More research on the most optimal physical activity intervention characteristics is needed.

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Section: Search Results and Flow Of Studies Through The Reviewmentioning

confidence: 99%

Cardiorespiratory fitness levels and moderators in people with HIV: A systematic review and meta-analysis

Vancampfort

Mugisha

Rosenbaum

et al. 2016

Preventive Medicine

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“…Some authors also report that exercise and physical activity may be positive to HIV patients reducing central and peripheral obesity which is associated with the HAART [26][27][28] . Improvement in physical conditioning with physical activity and exercise represents better levels of actual energy for activities including leisure activities.…”

Section: Discussionmentioning

confidence: 99%

Níveis de atividade física e alterações metabólicas em pessoas vivendo com HIV/AIDS

Romancini

Guariglia

Nardo

et al. 2012

Rev Bras Med Esporte

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The introduction of Highly Active Antiretroviral Therapy (HAART) has deeply changed the course of HIV infection with increase in survival and improvement in quality of life as well as partial restoration of the immune system. After about ten years from the HAART use, the effects of combination treatment / virus started to come out. Among these, we can mention changes in lipid metabolism with hypertriglyceridemia, hypercholesterolemia, insulin resistance, hyperglycemia and redistribution of body fat as risk factors for cardiovascular disease. Observational studies with people living with HIV / AIDS evidence that when an individual finds out that he/she is an HIV/AIDS patient, he/she end ups feeling fear or shame, reducing hence social circle, work and leisure activities, and becomes isolated at home or in small groups which have common identity of HIV / AIDS patients. The purpose of this work was to evaluate the relationship between the level of habitual physical activity and recreation of people living with HIV / AIDS and its relation with metabolic changes. The patients were classified into active and sedentary, using the Habitual Physical Activity questionnaire proposed by Baecke and validated for HIV / AIDS patients. Classification was conducted according to the recommendations of the American College of Sports Medicine. Metabolism was assessed through plasma levels of glucose, total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides, using commercial kits. The sample consisted of 65 HIV patients who used HAART for at least five years. 64.6% were classified as sedentary and 35.4% as active. The study shows a direct relationship between physical activity level and higher levels of HDL -cholesterol in HIV / AIDS. HDL -Cholesterol is a lipoprotein of cardiovascular protection and, although other assessed parameters have not shown difference, these results highlight the need for additional studies on risk factors and physical activity for HIV / AIDS enabling proposals for specific interventions for these patients.

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“…Considerando os treinamentos aeróbios e de força, foram localizados quatro estudos: Terry et al (24) , Smith et al (25) , Yarasheski et al (26) e Lindegaard et al (27) . Terry et al (24) <I> em estudo randomizado com 30 pacientes HIV positivos com uso de TARV e dislipidemia, verificaram o VO 2pico , a composição corporal, a contagem de T-CD4+, a carga viral e o perfil lipídico em um programa de exercícios aeróbios.…”

Section: Treinamentos Aeróbio E De Forçaunclassified

“…Smith et al (25) <I> realizaram estudo randomizado com 60 pacientes HIV positivos (52 homens e oito mulheres) alocados em dois grupos, sendo que 30 eram do grupo experimental e 30 do grupo controle; entretanto, somente 19 participantes do grupo experimental finalizaram o treinamento. Foram avaliadas a fadiga, dispneia, volume expiratório forçado, massa corporal total e composição corporal em programa supervisionado de exercícios aeróbios, sendo que o grupo controle realizava suas atividades habituais.…”

Section: Treinamentos Aeróbio E De Forçaunclassified

Treinamento físico na síndrome lipodistrófica: revisão sistemática

Juchem

Lazzarotto

2010

Rev Bras Med Esporte

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Com a cronicidade da infecção pelo HIV, a partir do uso da terapia antirretroviral combinada (TARV), o indivíduo torna-se predisposto às alterações metabólicas e corporais denominadas síndrome lipodistrófica, que têm como consequência o risco aumentado para doenças cardiovasculares. Tornam-se necessários estudos com viabilidades terapêuticas com o intuito de melhorar a qualidade de vida destes pacientes. Neste contexto, o treinamento físico deve ser abordado como terapêutica para minimizar os efeitos deletérios da TARV. O objetivo desse artigo foi revisar na literatura as evidências científicas sobre o treinamento físico na síndrome lipodistrófica. O método utilizado foi uma revisão sistemática com a localização de artigos publicados entre 2000 e 2008 nas bases de dados PubMed e SciELO. As evidências científicas encontradas nos estudos analisados indicam que a maioria dos estudos, independente do tipo de treinamento, obtiveram melhoria significativa na composição corporal. Dessa forma, tornam-se necessário mais estudos investigando o treinamento físico no perfil lipídico, na resistência a insulina e nas alterações glicêmicas em pessoas vivendo com HIV/Aids.

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Aerobic exercise: effects on parameters related to fatigue, dyspnea, weight and body composition in HIV-infected adults

Abstract: We conclude that supervised aerobic exercise training safely decreases fatigue, weight, BMI, subcutaneous fat and abdominal girth (central fat) in HIV-1-infected individuals. It did not appear to have an effect on dyspnea.

Cited by 130 publications

References 25 publications

Cardiorespiratory fitness levels and moderators in people with HIV: A systematic review and meta-analysis

Cardiorespiratory fitness levels and moderators in people with HIV: A systematic review and meta-analysis

Níveis de atividade física e alterações metabólicas em pessoas vivendo com HIV/AIDS

Treinamento físico na síndrome lipodistrófica: revisão sistemática

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