Aeroallergene von zunehmender Bedeutung f�r die allergische Rhinitis

Rudack, Claudia; Sachse, F.; Jörg, S.

doi:10.1007/s00106-003-0917-8

Cited by 3 publications

(1 citation statement)

References 64 publications

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“…Dabei hat die Zahl der an Pollinosis erkrankten Erwachsenen in Deutschland zwischen 1990 und 1998 um 70% zugenommen. Der Heuschnupfen hat damit auf gesellschaftlicher Ebene eine grosse sozioökonomische Bedeutung, die vermutlich in Zukunft noch wachsen wird [1]. Die Relevanz der Darmflora für das Immunsystem ist unumstritten [2].…”

Section: Introductionunclassified

Immunmodulation mit Kanne-Brottrunk® zur Prävention bei Pollinosis: Eine einjährige Beobachtungsstudie mit Follow-up

2006

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The immune enhancing properties of probiotics are scientifically well documented. Whether Kanne- Brottrunk® (Selm-Bork, Germany) may play a preventive role in Pollinosis, was investigated in this study for the first time. Participants and Methods: 30 volunteers with pollinosis and a mean disease duration of 20 years agreed to consume 0.7 l Kanne-Brottrunk® daily for one year. At the beginning and at the end of the study and one year later they retrospectively rated their pollinosis related quality of life during the previous pollinosis season with a disease specific questionnaire (FLQA: Freiburg Life Quality Assessment). Additionally, the change was rated directly and status was assessed in November 2002, January 2003, May 2003 and November 2003. Results: 24 volunteers finished the study, although some of them consumed less than 0.7 l daily. 17 out of 20 assessed participants (85%) rated their pollinosis in the treatment year as ‘very much better’ or ‘much better’ (57% in the follow-up year). In 2003, the FLQA showed clinically relevant effect sizes (0.85-2.29) and statistically significant improvements (p < 0.05) for all six scales. In 2004, the improvements were slightly less pronounced (effect sizes 0.89-1.53) and were statistically significant for 4 scales (p < 0.05). 12 patients reported a relevant reduction or cessation of medication and many reported improvements of other immune related conditions Conclusions: The observed improvements under regular daily consumption of Kanne-Brottrunk® were marked and statistically significant. A randomized controlled trial would be necessary to allow causal conclusions.

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Section: Introductionunclassified

Immunmodulation mit Kanne-Brottrunk® zur Prävention bei Pollinosis: Eine einjährige Beobachtungsstudie mit Follow-up

2006

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Die Anwendung lipidhaltiger Nasensalbe bei allergischer Rhinitis — eine Therapieoption?

Geisthoff

Rupp-Classen²,

Blum

et al. 2005

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The test agent used in our study contains a lipid fraction, in this case in the form of high purity, long chain hydrocarbons. By local application, a significant improvement of the total symptomatology was shown. The mechanism has not been clarified. Owing to the efficacy and low risk of side effects, this seems to be a promising adjuvant therapy for allergic rhinitis. The probetoric use of this nasal ointment as a supportive therapeutic option should be reviewed in further clinical studies.

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Quality of life and healthcare costs of patients with allergic respiratory diseases: a cross-sectional study

et al. 2023

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Background Allergic rhinitis (AR) and allergic asthma (AA) are chronic respiratory diseases that represent a global health problem. One aim of this study was to analyze the Health-related Quality of Life (HRQoL) of the patients in order to identify statistically significant influencing factors that determine HRQoL. Another aim was to assess and analyze data on cost-of-illness from a statutory health insurance perspective. Methods The EQ-5D-5L was used to evaluate the patients’ HRQoL. To identify the factors influencing the HRQoL, a multinomial logistic regression analysis was conducted using groups based on the EQ-5D-5L index value as dependent variable. Routine data were analyzed to determine total healthcare costs. Results The average EQ-5D-5L index was 0.85 (SD 0.20). A high age, the amount of disease costs, low internal health-related control beliefs and high ozone exposure in the residential area were found to be statistically significant influencing factors for a low HRQoL, whereas low age, male sex and a good possibility to avoid the allergens were found to be statistically significant factors influencing a high HRQoL. On average, the study participants incurred annual costs of €3072 (SD: 3485), of which €699 (SD: 743) could be assigned to allergic respiratory diseases. Conclusions Overall, the patients in the VerSITA study showed a high level of HRQoL. The identified influencing factors can be used as starting points for improving the HRQoL of patients with allergic respiratory diseases. From the perspective of a statutory health insurance, per person expenditures for allergic respiratory diseases are rather low.

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Aeroallergene von zunehmender Bedeutung f�r die allergische Rhinitis

Cited by 3 publications

References 64 publications

Immunmodulation mit Kanne-Brottrunk® zur Prävention bei Pollinosis: Eine einjährige Beobachtungsstudie mit Follow-up

Immunmodulation mit Kanne-Brottrunk® zur Prävention bei Pollinosis: Eine einjährige Beobachtungsstudie mit Follow-up

Die Anwendung lipidhaltiger Nasensalbe bei allergischer Rhinitis — eine Therapieoption?

Quality of life and healthcare costs of patients with allergic respiratory diseases: a cross-sectional study

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