Aeroalergen distribution in skin prick test in children who were diagnosed with asthma and allergic rhinitis in Malatya region.

Abstract

Amaç: Astım ve alerjik rinit tanısı konulmuş çocukların aeroalerjenlere karşı duyarlılıkların dağılımını belirlemektir. Yöntem: İnönü Üniversitesi Pediatrik Alerji ve Astım polikliniğinde Haziran 2012 ile Mayıs 2013 tarihleri arasında astım ve alerjik rinit tanısı konulan çocukların dosyaların-dan deri prik test sonuçları geriye dönük olarak incelendi. Bulgular: Deri prik testi yapılan 358 hastanın 229 (%64) u en az bir aeroalerjene karşı duyarlı idi. Deri testinde pozitiflik tespit edilen hastaların ortanca yaşı 10 (5-18) olup, 138 (%60,3)'i erkek idi. En sık duyarlılığın tespit edildiği aeroalerjen ot/tahıl polen idi ve 112 hastada (%48,9) pozitif bulundu. Deri prik testinde pozitif bulunan aeroalerjenlerin sıklığı sırasıyla; yabani ot karışımı (48,5%), ev tozu akarı (40,2%), ağaç poleni karışımı (35,4%), hamam böceği (30,6%), mantar karışımı (27,5%), kedi ve köpek epiteli (26,6%) idi. Deri prik testi pozitif olan hastaların 51 (%25,3)'inde sadece bir aeroalerjene karşı duyarlılık varken, 171 hastada (%74,7) birden fazla aeroalerjene karşı duyarlılık vardı. Tek alerjene duyarlı olma ile hastaların cinsiyeti, yaşı, periferik eozinofili ve serum Ig E düzeyleri arasında istatistiksel olarak anlamlı bir ilişki yoktu. Bununla birlikte, astımlı hastaların birden fazla aeroalerjene karşı duyarlanmaları alerjik rinitli hastalara göre daha az idi (p=0,06). Sonuç: Kliniğimizde yapılan deri prik testinde en sık ot/tahıl polen karışımına karşı duyarlılık tespit edildi. Astımlı hastalar daha çok tek alerjene karşı duyarlanma eğilimindeydiler.

Preparedness and Knowledge Level of Family Physicians Regarding Anaphylaxis Diagnosis and Management

“…As has been reported in previous studies, the awareness and knowledge level of EAIs was inadequate among participants in this study (Prince et al, 2018;Topal et al, 2014;González-Díaz, et al, 2021;Yildiz et al, 2022). We analyzed and compared the percentages of FPs with adequate knowledge regarding diagnosis, acute treatment, and EAIs, our results indicate that older age and longer duration of work experience did not significantly influence knowledge of anaphylaxis, similar to the results of a previous study in Turkey (Topal et al, 2014;Yildiz et al, 2022). In contrast to recent study by Arga et al (2021), having clinical experience with or without epinephrine treatment had no statistically significant impact on the rates of adequate knowledge among participants in our study.…”

“…Current guidelines recommend that individuals who have experienced anaphylaxis and those at risk of anaphylaxis should be prescribed and carry an EAI at all times for emergency use (Cardona et al, 2020;Muraro et al, 2022). As has been reported in previous studies, the awareness and knowledge level of EAIs was inadequate among participants in this study (Prince et al, 2018;Topal et al, 2014;González-Díaz, et al, 2021;Yildiz et al, 2022). We analyzed and compared the percentages of FPs with adequate knowledge regarding diagnosis, acute treatment, and EAIs, our results indicate that older age and longer duration of work experience did not significantly influence knowledge of anaphylaxis, similar to the results of a previous study in Turkey (Topal et al, 2014;Yildiz et al, 2022).…”

“…Early diagnosis and proper management of this potentially life-threatening condition thus remain an important issue for international and national health associations. Due to the rising prevalence of anaphylaxis in children and adults, there is a growing body of work in Turkey studying the recognition and treatment of anaphylaxis using an EAI among physicians, teachers, and families (Tuncel et al, 2021;Ercan et al, 2012;Arga et al, 2021;Topal et al, 2014). Family physicians (FPs) are the primary first-line healthcare providers and should thus be prepared for this medical emergency to reduce its associated mortality and morbidity.…”

“…Family physicians (FPs) are the primary first-line healthcare providers and should thus be prepared for this medical emergency to reduce its associated mortality and morbidity. However, no studies have been conducted in Turkey on anaphylaxis knowledge among FPs, and very little is known regarding their awareness of EAI use in anaphylaxis management (Topal et al, 2014). Therefore, this study aimed to evaluate the baseline knowledge and awareness levels of FPs from different academic and employment positions in Sivas, Turkey, regarding the recognition of anaphylaxis symptoms in clinical scenarios, the use of epinephrine in acute treatment, and the role of EAIs in long-term treatment.…”

The distribution of sensitization to common aeroallergens in patients with rhinitis and asthma in Şanlıurfa, Türkiye

“…The hot and dry climate of the Şanlıurfa region, which is predominantly agricultural, explains the high frequency of detection of sensitization to grass pollens on skin tests in our study. In previous studies in the regions of Malatya (48.9%), Adıyaman (77.5%), and Diyarbakır (70.4%), which have a similarly hot and dry climate, sensitivity to pollen (grass and cereal mixtures) has been most frequently reported ( 4 , 18 , 19 ). In another study in Şanlıurfa (n= 38), the most common allergen sensitivities have been found as grass (39.5%) and cereal mixtures (34.2%) ( 20 ).…”