Adverse reaction to potassium iodide from a cough syrup

Muñoz, Francisco J.; Bellido, J.; Moyano, J. C.; Álvarez, María José; Juan, J

doi:10.1111/j.1398-9995.1997.tb02556.x

Cited by 11 publications

(7 citation statements)

References 5 publications

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“…An oral challenge test (~300 mg KI) caused similar symptoms 5 h after the test. 3 The present case's symptoms also appeared several hours after taking the second dose of 10% KI solution. In fact, the dose of KI for sporotrichosis (beginning at 600 mg, 12 drops, three times daily for an adult) is much higher than that of KI for cough (250 mg three times daily).…”

supporting

confidence: 55%

“…In the past century, oral potassium iodide (KI) has been shown to be an economical and effective medication for a variety of inflammatory dermatoses and sporotrichosis 1 . Although adverse effects to iodinated contrast media are common, 2 only one case of adverse reaction to a KI‐containing cough syrup has been reported 3 . We describe a case of edematous reaction during oral 10% KI treatment in a boy with sporotrichosis.…”

mentioning

confidence: 96%

“…1 Although adverse effects to iodinated contrast media are common, 2 only one case of adverse reaction to a KI-containing cough syrup has been reported. 3 We describe a case of edematous reaction during oral 10% KI treatment in a boy with sporotrichosis.…”

mentioning

confidence: 98%

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Prominent facial edema caused by potassium iodide solution in a patient with sporotrichosis

Xiao¹,

Lin²,

Chen³

2009

The Journal of Dermatology

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supporting

confidence: 55%

mentioning

confidence: 96%

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Prominent facial edema caused by potassium iodide solution in a patient with sporotrichosis

Xiao¹,

Lin²,

Chen³

2009

The Journal of Dermatology

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“…Other reactions are productive cough, pulmonary edema, swelling/tenderness of parotid and submaxillary glands, and inflammation of pharynx/larynx/tonsil may also occur (10). Hypersensitivity reactions such as angioedema, cutaneous and mucosal hemorrhage, signs and symptoms resembling serum sickness (e.g., fever, arthralgias, lymph node enlargement, eosinophilia) can occur (11,12).…”

Section: Discussionmentioning

confidence: 99%

Acute Ioderma: an Uncommon Serious Adverse Event Associated with Saturated Solution of Potassium Iodide Treatment

Rivero

Cochran

Celi

2018

AACE Clinical Case Reports

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Objective:The objective of this report is to raise awareness of a case with acute life-threatening ioderma, an uncommon adverse event of saturated solution of potassium iodide (SSKI) therapy. Although extremely rare, physicians should consider the potential for ioderma development as a dangerous but treatable side effect of SSKI therapy.Methods: We present a case report of an uncommon serious adverse event associated with SSKI therapy.Results: A 67-year-old woman with mutlinodular goiter and subclinical hyperthyroidism was prescribed SSKI in preparation for total thyroidectomy. Unfortunately, the patient disregarded the instructions and took the equivalent of three doses at once without any fluid. Six hours later, she developed a reaction characterized by angioedema and hemorrhagic papulo-vesicular rash involving the oral mucosa and her extremities, sparing the trunk. The patient was hospitalized and treated with corticosteroids with prompt resolution of her symptoms. Subsequently, she underwent successful total thyroidectomy. Conclusion: SSKI is considered a safe and effective drug rarely associated with dermatologic side effects. Ioderma is an idiopathic reaction characterized by acneiform, vesicular pustular, hemorrhagic, or urticarial lesions. Other systemic side effects of SSKI include urticaria, fever, eosinophilia, jaundice, pruritus, angioedema, and bronchospasm. High-dose steroid is the therapy of choice, with prompt regression of the symptomatology. Physicians should consider this rare, severe, but treatable condition when prescribing SSKI. (AACE Clinical Case Rep. 2018;4:e127-e130) Abbreviation: SSKI = saturated solution of potassium iodide CASE REPORTA 67-year-old female with a 10-year history of hyperthyroidism secondary to toxic multinodular goiter present-e128 SSKI-Induced Dermatopathy, AACE Clinical Case Rep. 2018;4(No. 2)

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“…Productive cough, pulmonary edema, swelling/ tenderness of parotid and submaxillary glands, inflammation of pharynx/larynx/tonsil may occur. [30] 4. Hypersensitivity reactions:-Angioedema, cutaneous and mucosal hemorrhage, signs and symptoms resembling serum sickness (e.g, fever, arthralgias, lymph node enlargement, eosinophilia) may occur.…”

Section: Wegener's Granulomatosismentioning

confidence: 99%