Adverse events following a third dose of measles, mumps, and rubella vaccine in a mumps outbreak

Impact of a Third Dose of Measles-Mumps-Rubella Vaccine on a Mumps Outbreak

“…[17][18][19][20][21] In 1976, mumps vaccine was administered to a proportion of the population during an epidemic of mumps on St. Paul Island, Alaska, and transmission among vaccinees stopped approximately a month earlier than among those who were unvaccinated. 19 Similarly, in 1986, at a time when only 1 dose of MMR vaccine was recommended in the United States, mumps vaccine was provided to 414 students and staff of a high school experiencing a mumps outbreak primarily among unvaccinated students.…”

“…18 Of those, 115 (7.2%) reported at least 1 local or systemic adverse event in the 2 weeks after vaccination. The most commonly reported adverse events were "pain, redness, or swelling at the injection site" (3.6%) and "joint or muscle aches" (1.8%).…”

Epidemiology and the economic assessment of a mumps outbreak in a highly vaccinated population, Orange County, New York, 2009–2010

“…The intervention, its impact and vaccine-related adverse events is described elsewhere. 19,37 Studies assessing the economic burden of a mumps outbreak are limited. Most of the cost during an outbreak is driven by contact/case-finding as these activities take the most amounts of time and resources.…”

Mumps Outbreak among Highly Vaccinated Teenagers and Children in the Central Region of Portugal, 2012-2013

“…12,30 Some authors have proposed the administration of a third dose of vaccine to compensate the decreased immunity over time that makes more susceptible to disease teenagers and young adults, groups in which complications are more frequent in particular orchitis. 16,30,31 Recruits vaccinated without record of previous vaccinations, escaped outbreaks in the United States in 2006. 12,16,31 Moreover, those inoculated with doses of vaccine containing the Rubini strain are less protected, forming a susceptible group which could promote virus circulation and thus outbreaks and would be prime candidates for a booster dose.…”

“…16,30,31 Recruits vaccinated without record of previous vaccinations, escaped outbreaks in the United States in 2006. 12,16,31 Moreover, those inoculated with doses of vaccine containing the Rubini strain are less protected, forming a susceptible group which could promote virus circulation and thus outbreaks and would be prime candidates for a booster dose.…”