Adverse effects of herbal medicine

Dwivedi, Shridhar; Chopra, Deepti

doi:10.7861/clinmedicine.13-4-417a

Cited by 6 publications

(6 citation statements)

References 2 publications

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“…Moreover, rigorous scientific proof of the effectiveness of phytotherapy in otorhinolaryngology is still lacking, and it is critical to be aware of the interactions with conventional treatment. However, further in-depth research, national and international legislation, and strict regulation are necessary for the controlled use, safety, and efficacy evaluation of these herbal drugs 5,7,24 .…”

Section: Discussionmentioning

confidence: 99%

“…More research is needed to clarify and determine the clinical significance of herb-drug interactions. It is critical for health professionals, patients, regulatory authorities, and herbal medicine suppliers to be aware of the potential ADRs and drug interactions that can occur when herbal medicines are used either alone or in combination with conventional drugs 7 . Additionally, many of them have unknown long-term effects, necessitating appropriate use, education, and research 6 .…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, many of them have unknown long-term effects, necessitating appropriate use, education, and research 6 . Therefore, it is important to conduct rigorous scientific procedures and clinical trials to guarantee the consistency and quality of herbal products 5,7 .…”

Section: Introductionmentioning

confidence: 99%

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Self-medication practices with conventional and herbal drugs among ear, nose, and throat patients

Kıroğlu

Berktaş

Khan

et al. 2022

Rev. Assoc. Med. Bras.

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OBJECTIVE: This study evaluates the self-practices with conventional and herbal drug use among ear, nose, and throat outpatients. METHODS: A cross-sectional survey-based study was carried out among all ear, nose, and throat outpatients on their first visit to the otorhinolaryngology department at a tertiary care hospital. The survey comprised a total of 14 questions with 4 different sections, including demographic characteristics, self-medication of conventional medicines, herbal medication usage, and perception regarding herbal medicines. RESULTS: Overall, 255 questionnaires were distributed among patients, of which 183 completed the questionnaire (response rate=71.7%). Respondents reported self-medication (44.8%) with conventional drugs before visiting a hospital. The most commonly used medicine was analgesics (31.7%) and antibiotics (21.9%). Nearly half of the patients (49.2%) used at least one herbal drug. The most commonly used herbal medications were Tilia cordata (78.8%), Zingiber officinale (62.2%), and Camellia sinensis (45.5%). According to the International Union for Conservation of Nature Red List, most of the medicinal herbs were considered as data deficient/least concern. About 36.6% of the participants perceived that herbal drugs are effective for ear, nose, and throat problems. Moreover, 22.9% of the patients did not know about herbal-drug interaction with other medications. CONCLUSIONS: This study observed a considerable prevalence of self-based practices with conventional and herbal medications. Strict national regulations on conventional and herbal medication access and long-term actions should be implemented to discourage inappropriate drug use.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Self-medication practices with conventional and herbal drugs among ear, nose, and throat patients

Kıroğlu

Berktaş

Khan

et al. 2022

Rev. Assoc. Med. Bras.

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“…Over 30% of all ADRs are caused by drug-drug interactions (DDIs), causing serious morbidity each year which warrants early detection [98]. Similarly, due to the upsurge of herbal supplements which are used alone or co-administered with conventional drugs, adverse reactions and drug interactions attributed to herbal supplements are becoming a significant safety concern [35,99].…”

Section: Table 7: Traditional Classification Of Herbal Adverse Reactionsmentioning

confidence: 99%

Clinical Implications of Herbal Supplements in Conventional Medical Practice: A US Perspective

Hassen¹,

Belete²,

Carrera³

et al. 2022

Cureus

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Herbal supplements are common complementary and alternative medicine (CAM) approaches with an everincreasing use trend in the last two decades among the US population. Self-medication with herbal supplements which are promoted for general well-being, weight loss, immunity, and memory boost, and mental and physical health claims are very prevalent. There is a misperception that herbal supplements are harmless as they are prepared from natural sources. Unlike conventional drugs, the US Food and Drug Administration (FDA) does not regulate herbal supplements for premarketing purity and potency. Hence, there is a growing concern for health risks due to misbranded toxic ingredients, contaminants, adulterants, and herb-drug interactions (HDI) with co-administered drugs. The spectrum of pharmacological and toxicological effects of herbal supplements includes deranged lab results, allergic reactions, genotoxicity, carcinogenicity, teratogenicity, organ damage, and even fatality contributing to sizable emergency visits and hospitalizations in the US. The use of herbal supplements should be carefully monitored in high-risk groups such as pediatric and geriatric populations, pregnant women, breastfeeding mothers, immunocompromised patients, and surgical candidates. The deleterious health effects of herbal supplements are loosely addressed in conventional medical practice in part due to the limited knowledge of practitioners. This comprehensive narrative review aims to explore the clinical implications of herbal supplements in order to fill the knowledge gaps by summarizing scientific publications. It also highlights the pivotal roles physicians can play in minimizing the health risks of herbal supplements by encouraging patients to disclose usage through a non-judgmental approach, employing HDI screening tools, and reporting adverse reactions to FDA. Formal training of physicians, a standardized pharmacovigilance system, stricter regulation of the herbal industry, and more scientific studies are keys to establishing herbal safety and efficacy in clinical practice.

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“…Due to the pervading marketing from HMP companies, dietary supplements sales are valued at $151.9 billion a year, with compounded annual growth rates estimated at 8.9% through 2030 27 . The prevailing assumption is that HMP's are natural ingredients and therefore “safe” for consumption, when in fact, HMP's contain pharmacologically active ingredients which can potentiate ADR 28 . The baby boomer cohort known for their self‐assured and resourceful nature, have been drawn to use these dietary supplements to treat their growing comorbidities.…”

Section: Introductionmentioning

confidence: 99%

Pharmacotherapeutic challenges for treating the baby boomer cohort

Pelok

2023

Special Care in Dentistry

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As the baby boomer cohort ages, they have an ever‐increasing number of comorbidities and associated poly‐pharmaceutical treatment needs. The challenge for healthcare providers is to stay current of advancements in providing for this aging population. Baby boomers can expect a longer life expectancy than any previous generation. Yet, longevity has not correlated with better health. This cohort is noted for being goal driven and more self‐assured than younger generations. They are resourceful and will often attempt to fix things themselves, including their healthcare. They believe hard work deserves justifiable rewards and relaxation. These beliefs have resulted in baby boomers utilizing more alcohol and illicit drugs. Altogether this means today's healthcare providers must be aware of potential interactions from the polypharmacy of prescribed medication, and they must include and understand additional complications associated with supplemental medications and illegal drugs.

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Adverse effects of herbal medicine

Cited by 6 publications

References 2 publications

Self-medication practices with conventional and herbal drugs among ear, nose, and throat patients

Self-medication practices with conventional and herbal drugs among ear, nose, and throat patients

Clinical Implications of Herbal Supplements in Conventional Medical Practice: A US Perspective

Pharmacotherapeutic challenges for treating the baby boomer cohort

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