Adverse birth outcomes and childhood caries: a cohort study

Abstract

Objectives To examine the association between adverse birth outcomes and dental caries in primary teeth. Methods This study included children in Khon Kaen, Thailand, who participated in the Prospective Cohort Study of Thai Children. Preterm was defined as a birth at <37 weeks gestation, low birthweight (LBW) as birthweight <2,500 grams, and small-for-gestational-age (SGA) as birthweight <10th percentile of expected weight for gestational age. Two calibrated dentists measured dental caries in primary teeth when the children were 3-4 years old using decayed, missing and filled surfaces (dmfs) index following the World Health Organization criteria. We used negative binomial regression with generalize linear models to estimate relative risks (RRs) and their 95% confidence intervals (CIs), adjusted for confounding factors. Of 758 children with gestational age data and 833 with birthweight data, the 544 (follow-up rate of 71.8% in preterm and 65.3% in LBW) who had dental data available were included in the analysis. Results Dental caries was observed in 480 children (88.2%), with a mean dmfs of 14.3 (standard deviation 12.8). The adjusted RR for dental caries was 0.61 (95%CI 0.43, 0.85) for preterm, 0.89 (95%CI 0.67, 1.21) for LBW, and 0.96 (95%CI 0.74, 1.26) for SGA. Conclusions There was an inverse association between preterm and childhood caries. LBW and SGA were not associated with dental caries in this population.

Dental Caries and Developmental Defects of Enamel in the Primary Dentition of Preterm Infants: Case-Control Observational Study

“…To the best of our knowledge, there were no other studies observing caries prevalence and experience within the birth weight categories ELBW, VLBW, and LBW. In the literature, LBW was not associated with dental caries in the primary dentition [Shulman, 2005;Tanaka and Miyake, 2014;Nirunsittirat et al, 2016]. The association between LBW and DDE found in other studies [Lunardelli and Peres, 2006;Ferrini et al, 2008;Velló et al, 2010;Takaoka et al, 2011;Cruvinel et al, 2012;Masumo et al, 2013;Nelson et al, 2013;Elfrink et al, 2014] was confirmed by the present data.…”

“…The differences were significant for the occurrence of cavitated and noncavitated caries lesions (ICDAS II criteria) and for caries experience (DMFT criteria). Few studies reported a higher caries prevalence in PTI [Saraiva et al, 2007;Carvalho et al, 2011], while others found nonsignificant lower caries prevalence in PTI compared to FTI [Burt and Pai, 2001;Cruvinel et al, 2010;Nelson et al, 2010;Rythen, 2012;Tanaka and Miyake, 2014;Nirunsittirat et al, 2016;Wagner and Heinrich-Weltzien, 2016]. Factors that may contribute to a higher risk of dental caries in PTI could be the impaired immune response leading to earlier colonization by cariogenic bacteria and the association of prematurity and LBW with deprived SES of the mother [Burt and Pai, 2001;Shulman, 2005].…”

“…Several studies found no association [Burt and Pai, 2001;Shulman, 2005;Tanaka and Miyake, 2014], while others found a higher caries risk [Saraiva et al, 2007;Nelson et al, 2010] or even a negative association [Nirunsittirat et al, 2016].…”

Adverse Birth Outcomes And Oral Health

“…We would like to congratulate Community Dentistry and Oral Epidemiology for the publication of the article 'Adverse birth outcomes and childhood caries: a cohort study' by Nirunsittirat et al 1 Indeed, it is vital to improve the understanding of early child's oral health determinants and consequent identification of interventions and behaviors that can be modified with health promotion activities since birth. Authors have suggested that proper fetal growth and adequate development in the first two years of life are determinants of health, not only at childhood but also in later life 2,3 .…”

Morphological Changes in Tooth Germs and Surrounding Tissues in Newborn Rats with Experimentally Induced Macrosomia

“…У зв'язку з широким поширенням хвороб тканин пародонта і твердих тканин зубів особлива увага вчених привертається до питань формування цих тканин. Віддалені наслідки перинатальної патології, зокрема вплив вагітності, яка патологічно протікає, на формування стоматологічних порушень на сьогоднішній день є парадигмою [1,2,3].…”