Advances in the development of organic polymer monolithic columns and their applications in food analysis—A review

Jandera, Pavel

doi:10.1016/j.chroma.2013.08.010

Cited by 112 publications

(62 citation statements)

References 235 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Polymer monolithic columns can provide high efficiency in gradient elution 148 showed that the calculated throughput, peak capacity, and identification score were similar for the two columns for single protein digests (BSA or Myoglobin), although the silica monolith provided slightly better results for a more complicated nine-protein digest.…”

Section: Performance In Gradient Elutionmentioning

confidence: 99%

Core–Shell, Ultrasmall Particles, Monoliths, and Other Support Materials in High-Performance Liquid Chromatography

Tanaka¹,

McCalley

2015

Anal. Chem.

150

View full text Add to dashboard Cite

Section: Performance In Gradient Elutionmentioning

confidence: 99%

Core–Shell, Ultrasmall Particles, Monoliths, and Other Support Materials in High-Performance Liquid Chromatography

Tanaka¹,

McCalley

2015

Anal. Chem.

150

View full text Add to dashboard Cite

“…15 The large pores of organic monoliths allow large biomacromolecules to go through easily; then, the biomolecules can be removed in the sample pretreatment process. 16 However, there are some disadvantages that limit the wider application of polymer monoliths in separation; these include their nonuniform structure and shrinking or swelling in the organic solvent. To improve the characteristics of polymer monoliths, ionic liquid (IL) has been used in the polymerization.…”

Section: Introductionmentioning

confidence: 99%

Determination of trace macrolide antibiotics in milk with online solid‐phase extraction with an ionic‐liquid‐based monolithic column

Liu

Zong

Wei

et al. 2016

J of Applied Polymer Sci

View full text Add to dashboard Cite

An ionic liquid (IL)-based monolithic poly(ionic liquid glycidylmethacrylate-co-ethylene glycol dimethacrylate) column was prepared via in situ free-radical polymerization with 1-vinyl-3-butylimidazolium chlorine as one of the comonomers. The obtained monolithic column was used as the sorbent of solid-phase extraction (SPE) and coupled with high-performance liquid chromatography for the simultaneous determination of the macrolide antibiotics roxithromycin (ROX) and acetylspiramycin (ACE) in processed pure milk. The monolithic column was characterized by Fourier transform infrared spectrometry, scanning electron microscopy, nitrogen absorption-desorption, mercury intrusion porosimetry, and thermogravimetric analysis. The results reveal that the monolithic column exhibited a high selectivity and good permeability to the macrolide antibiotics in milk. The optimized method offered excellent linearity with a linear regression coefficient greater than 0.998. The precisions for interday and intraday were both less than 7.7%. The accuracies expressed by the recoveries for ROX and ACE were in the ranges 92.5-103.8 and 93.0-107.6%, respectively. Compared to the previous methods, this method had a low limit of detection and a good accuracy. As a result, the polymer IL based monolithic column could feasibly be used as a high-selectivity online SPE sorbent for determining trace macrolide antibiotics in milk.

show abstract

“…So far, only UHPLC methods using sub-2-µm particulate columns fulfil this demand, offering analysis times in the 5-min range. Alternative solutions employ a conventional HPLC instrumentation with monolithic columns, allowing faster analysis than the particle-packed columns of the same length at the same operating pressure [9,57]. Recently, a simple and sensitive method for the quantification of malachite green in fish feed was developed using a commercial LC C18 monolithic column in combination with mass spectrometry [44].…”

Section: Lc and Gc Separationsmentioning

confidence: 99%

“…The presence of mesopores increases the total pore surface area and sample capacity of monolithic beds. The structure of monolithic media can be represented as a network of small mesopores, which are responsible for the retention and separation selectivity, interconnected by large flow-through pores [9], and this should lead to higher permeability. Thus, you can get fast separations at the high flow of the mobile phase and moderate back-pressures in comparison to particle-packed columns with similar efficiency [10].…”

Section: Monoliths: General Featuresmentioning

confidence: 99%

Recent Advances and Uses of Monolithic Columns for the Analysis of Residues and Contaminants in Food

et al. 2015

View full text Add to dashboard Cite

Abstract:Monolithic columns are gaining interest as excellent substitutes to conventional particle-packed columns. These columns show higher permeability and lower flow resistance than conventional liquid chromatography columns, providing high-throughput performance, resolution and separation in short run times. Monoliths possess also great potential for the clean-up and preparation of complex mixtures. In situ polymerization inside appropriate supports allows the development of several microextraction formats, such as in-tube solid-phase and pipette tip-based extractions. These techniques using porous monoliths offer several advantages, including miniaturization and on-line coupling with analytical instruments. Additionally, monoliths are ideal support media for imprinting template-specific sites, resulting in the so-called molecularly-imprinted monoliths, with ultra-high selectivity. In this review, time-saving LC columns and preparative applications applied to the analysis of residues and contaminants in food in 2010-2014 are described, focusing on recent improvements in design and with emphasis in automated on-line systems and innovative materials and formats.

show abstract

Advances in the development of organic polymer monolithic columns and their applications in food analysis—A review

Cited by 112 publications

References 235 publications

Core–Shell, Ultrasmall Particles, Monoliths, and Other Support Materials in High-Performance Liquid Chromatography

Core–Shell, Ultrasmall Particles, Monoliths, and Other Support Materials in High-Performance Liquid Chromatography

Determination of trace macrolide antibiotics in milk with online solid‐phase extraction with an ionic‐liquid‐based monolithic column

Recent Advances and Uses of Monolithic Columns for the Analysis of Residues and Contaminants in Food

Contact Info

Product

Resources

About