Advances in nanotechnology, nanopollution, nanotoxicology, and nanomedicine

Abstract

Nanotechnology is a science that deals with the design, characterization, synthesis, and application of nanoscale materials (1-100 nm). Nanomaterials (NMs) have unique physicochemical characteristics, including ultra-small size, large surface area to mass ratio, and high reactivity. Nanomedicine is the application of nanotechnology in medicine to advance diagnostic, preventive, and therapeutic strategies. The potent antioxidant properties of some NMs open the door to develop new therapies with enhanced, targeted actions. However, oxidative stress is the main adverse effect of metallic oxide NMs, such as nickel oxide, zinc oxide, and titanium dioxide. Therefore, NMs have double-edged effects on cellular redox hemostasis. Recently, many researchers have focused on the ecological and safety issues of synthetic NMs to reduce the risk of their toxicity. The present special issue "Advances in Nanotechnology, Nanopollution, Nanotoxicology and Nanomedicine (ANNNN)" is dedicated to integrate the previous and the current biological, medical, and ecological data on NMs.

Assessment of anti-inflammatory properties of metal nanoparticles as potential means for the correction of pathologies on the reproductive system in animals

“…Численні типи запалень, викликаних чужорідними патогенами або хімічними речовинами, і мутації, які посилюють інгібітори запалення, обумовлюють потребу в розробці нових засобів з вираженою протизапальною ефективністю [1]. За останнє десятиліття було досягнуто величезного прогресу в тому, щоб зробити комерційно доступними терапевтичні продукти та препарати на основі наночастинок (НЧ) [2][3][4]. Завдяки вражаючим досягненням у нанотехнологіях було досліджено наноматеріали з унікальними регулюючими властивостями щодо активних форм Оксигену (АФО), щоб керувати тимчасово-просторовою динамічною поведінкою АФО у біологічному середовищі, що сприяє появі терапевтичної методології нового покоління, тобто керованої наноматеріалами еволюції АФО in vivo для терапевтичних заходів [5,6].…”

A Review on Concept of Nanotechnology in Veterinary Medicine

“…Further research is still needed before such technology can be translated into effective products for in vivo use. [113][114][115][116] Toxic effects of nanoparticles Toxicology is the branch of biology, chemistry and medicine concerned with the adverse effects of chemicals on living organisms. In toxicology we study the symptoms, mechanisms, treatment and detection of poisoning especially the poisoning of animals and human.…”

Nanomaterials augmented bioeffects of ultrasound in cancer immunotherapy

“…With the rapid development of molecular engineering and synthetic biology, various nanomaterials have been used to construct ultrasound responsive nanoplatforms, which improve the bioeffects of ultrasound, promote the progress of ultrasound mediated immunotherapy and achieve high therapeutic efficacy [ [15] , [16] , [17] , [18] ]. These nanoplatforms not only modulate the tumor immunosuppressive microenvironment and restore immune surveillance, but also utilize the biological effects of ultrasound to further enhance antitumor efficacy, not only for the primary tumor, but also for metastatic and recurrent tumors [ 19 ].…”