Advances in Chitosan Material and its Hybrid Derivatives: A Review

Lee, Duck Weon; Lim, Ho-Sun; Chong, Ha Na; Shim, Woo Sub

doi:10.2174/1876502500901010010

Cited by 95 publications

(48 citation statements)

References 97 publications

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“…Besides these adsorptive properties, the amino groups as well as some hydroxyl groups are chemically reactive, which makes chitosan amenable to chemical modification (1,2). Based on these unique properties, chitosan has been used in a variety of fields, including water purification and the food, chemical, and medical industries (3)(4)(5). Chitosan is industrially produced by chemical deacetylation of chitin, primarily that derived from crustacean shell waste.…”

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confidence: 99%

Applied Usage of Yeast Spores as Chitosan Beads

Zhang

Tachikawa

Gao

et al. 2014

Appl Environ Microbiol

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bIn this study, we present a nonhazardous biological method of producing chitosan beads using the budding yeast Saccharomyces cerevisiae. Yeast cells cultured under conditions of nutritional starvation cease vegetative growth and instead form spores. The spore wall has a multilaminar structure with the chitosan layer as the second outermost layer. Thus, removal of the outermost dityrosine layer by disruption of the DIT1 gene, which is required for dityrosine synthesis, leads to exposure of the chitosan layer at the spore surface. In this way, spores can be made to resemble chitosan beads. Chitosan has adsorptive features and can be used to remove heavy metals and negatively charged molecules from solution. Consistent with this practical application, we find that spores are capable of adsorbing heavy metals such as Cu 2؉ , Cr 3؉ , and Cd 2؉ , and removal of the dityrosine layer further improves the adsorption. Removal of the chitosan layer decreases the adsorption, indicating that chitosan works as an adsorbent in the spores. Besides heavy metals, spores can also adsorb a negatively charged cholesterol derivative, taurocholic acid. Furthermore, chitosan is amenable to chemical modifications, and, consistent with this property, dit1⌬ spores can serve as a carrier for immobilization of enzymes. Given that yeast spores are a natural product, our results demonstrate that they, and especially dit1⌬ mutants, can be used as chitosan beads and used for multiple purposes.

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mentioning

confidence: 99%

Applied Usage of Yeast Spores as Chitosan Beads

Zhang

Tachikawa

Gao

et al. 2014

Appl Environ Microbiol

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“…The buriti growth is slow, this palm has a single trunk and presents difficulties for vegetative reproduction, since it demands a great amount of water for its satisfactory development. In order to be cultivated in crops, this species presents great limitations and sustainable management techniques should be encouraged and improved, as the areas of buriti occurrence are considered Permanent Protection Areas (APP), which is a place where all forests must be maintained and other forms of natural vegetation and should not be modified to other types of occupancy [60][61][62]. The buriti (Mauritia flexuosa L.) popularly known as Canadaguaçu, smell of coconut, miriti, palm of the marsh, among others, is a palm tree of the family Arecaceae, native of Brazil, with great socioeconomic potential.…”

Section: Buriti (Mauritia Flexuosa L) General Characteristics Of Thementioning

confidence: 99%

Application of Chitosan and Buriti Oil (Mauritia Flexuosa L.) in Skin Wound Healing

Rfj

Pighinelli

2017

JABB

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Wound is the breakdown of the structure and normal functions of the integument and its healing process. The wound healing process is common to all tissues and is characterized by three stages: inflammation, proliferation (fibroblast phase) and remodelling. Many substances are used to improve and accelerate this process. A polymer that comes to the attention of researchers is chitosan, which is obtained by the deacetylation of chitin. Another substance that shows good results in the healing process is buriti oil, extracted mainly from the fruit bulb of Mauritia flexuosa L. The main objective of this study is to demonstrate through bibliographical research the effects of chitosan and buriti oil on healing, as well as describing the process of obtaining chitosan and buriti oil and characterizing chitosan and buriti oil. This is an exploratory study where the bibliographical review was used as technical procedure. For the elaboration of the study, we used scientific materials already published, consisting mainly of theses, dissertations, books, articles of scientific journals and annals of scientific congresses, observing the temporal limits between 2000 and 2016. A potential use of chitosan and oil of buriti in the healing of cutaneous wounds since they presented good results in all the phases of tissue repair. Chitosan has been characterized as being biodegradable, biocompatible has free amine groups thus becoming well reactive, the oil has an orange-coloured liquid, rich in carotenoids (β-carotene), α-tocopherol (vitamin E) And fatty acids. It is expected that this study can serve as a reference for studies on these substances, as well as that they can be used together in order to potentiate their effects on the healing process.

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“…The deacetylated form of chitin refers to chitosan (Lee et al, 2009). Basically, the process consists of deproteinization of the raw shell material with a dilute NaOH solution and decalcification with a dilute HCl solution.…”

Section: Chitosanmentioning

confidence: 99%

Potential Applications of Chitosan Nanoparticles as Novel Support in Enzyme Immobilization

Malmiri

Jahanian

Berenjian

2012

American Journal of Biochemistry and Biotechnology

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Chitosan is an attractive natural biopolymer from renewable resources with the presence of reactive amino and hydroxyl functional groups in its structure. Due to the good biocompatibility of chitosan, it can be used in magnetic-field assisted drug delivery, enzyme or cell immobilization and many other industrial applications. In the past decade, nanotechnology has been a considerable research interest in the area of preparation of immobilized enzyme carriers. This study looks at characteristics and applications of chitosan and chitosan nanoparticles and their potentials as suitable supports for enzyme immobilization. Results indicated that activity of immobilized enzymes and performance of enzyme immobilization onto chitosan nanoparticles are higher than chitosan macro and microparticles. As compared to other biopolymers nanoparticles, application of chitosan nanoparticles to immobilize enzymes strongly increases stability of immobilized enzymes and their easy separability from the reaction mixture at the end of the biochemical process.

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Advances in Chitosan Material and its Hybrid Derivatives: A Review

Cited by 95 publications

References 97 publications

Applied Usage of Yeast Spores as Chitosan Beads

Applied Usage of Yeast Spores as Chitosan Beads

Application of Chitosan and Buriti Oil (Mauritia Flexuosa L.) in Skin Wound Healing

Potential Applications of Chitosan Nanoparticles as Novel Support in Enzyme Immobilization

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