Application of Chitosan and Buriti Oil (Mauritia Flexuosa L.) in Skin Wound Healing

Abstract

Wound is the breakdown of the structure and normal functions of the integument and its healing process. The wound healing process is common to all tissues and is characterized by three stages: inflammation, proliferation (fibroblast phase) and remodelling. Many substances are used to improve and accelerate this process. A polymer that comes to the attention of researchers is chitosan, which is obtained by the deacetylation of chitin. Another substance that shows good results in the healing process is buriti oil, extracted mainly from the fruit bulb of Mauritia flexuosa L. The main objective of this study is to demonstrate through bibliographical research the effects of chitosan and buriti oil on healing, as well as describing the process of obtaining chitosan and buriti oil and characterizing chitosan and buriti oil. This is an exploratory study where the bibliographical review was used as technical procedure. For the elaboration of the study, we used scientific materials already published, consisting mainly of theses, dissertations, books, articles of scientific journals and annals of scientific congresses, observing the temporal limits between 2000 and 2016. A potential use of chitosan and oil of buriti in the healing of cutaneous wounds since they presented good results in all the phases of tissue repair. Chitosan has been characterized as being biodegradable, biocompatible has free amine groups thus becoming well reactive, the oil has an orange-coloured liquid, rich in carotenoids (β-carotene), α-tocopherol (vitamin E) And fatty acids. It is expected that this study can serve as a reference for studies on these substances, as well as that they can be used together in order to potentiate their effects on the healing process.

ESTUDO DA TOXICIDADE DE Combretum leprosum Mart.: TESTE ALLIUM CEPA

“…The particle size of nanoparticulate chitosan originated from agglomeration process ranges from 20 nm for 120 nm, with an average of 55,4 nm (PIGHINELLI, 2017) proliferation (fibroblast phase. The results are illustrated in It is noted an increase in particle sizes of NCCH/B biocomposite (134 nm) when compared to NCCH (85 nm).…”