Advances in Blood Typing

Quraishy, NurJehan; Sapatnekar, Suneeti

doi:10.1016/bs.acc.2016.06.006

Cited by 23 publications

(31 citation statements)

References 99 publications

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“…In the meantime, the current recommendation of transfusing DEA 1- or DEA 1 matched blood at time of first transfusion initially and also crossmatch compatible blood for any subsequent transfusion (>4 days) may be extended to including typing for Kai dogs with incompatible crossmatch to find more readily compatible donors which had been also typed from Kai [18]. It should be noted that despite 36 blood group system and 352 antigens in humans [25], routine typing remains fairly restricted to ABO and Rh (and possibly Kell) unless in special circumstances or when the patient is found to be crossmatch incompatible [26]. …”

Section: Discussionmentioning

confidence: 99%

Kai 1 and Kai 2: Characterization of these dog erythrocyte antigens by monoclonal antibodies

2017

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Dog Erythrocyte Antigens (DEA) have thus far been found by sensitizing dogs with canine allogeneic blood and are clinically important regarding blood transfusion incompatibilities, but remain poorly defined. The goals of this study were to discover and characterize two DEAs, named as Kai 1 and Kai 2. The monoclonal antibodies were produced by mouse hybridoma techniques and examined by ELISA isotyping, immunoblotting, and affinity chromatography. Canine blood samples were typed and the development of alloantibodies was examined in transfused dogs. The monoclonal Kai 1 and Kai 2 antibodies were isotyped as IgM kappa and IgG3 lamda, respectively, and identified two different erythrocyte membrane proteins of 200 kDa and 80 kDa in molecular weights, respectively. Either Kai 1 or Kai 2 can be expressed but not both in an individual dog. There were no naturally occurring anti-Kai 1 or Kai 2 alloantibodies. In addition, Kai 1- and/or Kai 2- dogs developed Kai 1 and Kai 2 alloantibodies, respectively, when transfused with mismatched blood. This is the first discovery of canine blood types by screening monoclonal antibodies. Kai 1 and Kai 2 are novel blood types which can induce anti-Kai 1 or anti-Kai 2 alloantibodies when Kai 1- and/or Kai 2- dogs are transfused with Kai 1+ or Kai 2+ blood. These canine blood types may explain some of the blood incompatibilities and transfusion reactions observed in dogs in clinical practice.

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Section: Discussionmentioning

confidence: 99%

Kai 1 and Kai 2: Characterization of these dog erythrocyte antigens by monoclonal antibodies

2017

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“…Like ABO types, Rh-type refers to proteins on surface of RBCs. 47 Clinically, this system plays an important role in blood transfusion and erythroblastosis fetalis. 47 , 48 Recent studies also demonstrate a significant impact in COVID-19 infection and illness as well.…”

Section: Rhesus Type and Covid-19mentioning

confidence: 99%

Relationship between blood type and outcomes following COVID-19 infection

Kim

Latz

DeCarlo

et al. 2021

Seminars in Vascular Surgery

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Since the onset of the COVID-19 pandemic, a concentrated research effort has been undertaken to elucidate risk factors underlying viral infection, severe illness, and death. Recent studies have investigated the association between blood type and COVID-19 infection. This article aims to comprehensively review current literature and better understand the impact of blood type on viral susceptibility and outcomes.

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“…17,18 In contrast to Wittels and Lichtman, Quraishy and Sapatnekar on the panel (2016) proposed that O was proposed to be susceptible of most as the group of ABO system as in blood group O, there is no anti A and anti B produced. 19 As in the theory of immunology explaining the development of sepsis, the condition is like those with no antibody produced when someone get infected with Gramnegative pathogen such as Escherichia coli as the common causal of sepsis to date. However, Escherichia coli and Klebsiella pneumonia are the most causal in Indonesia, instead of Pseudomonas aeruginosa.…”

Section: Discussionmentioning

confidence: 99%

Correlation between Blood Types and Intraabdominal Infection A Preliminary Study

Robby

Moenadjat

2018

NRJS

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Introduction. Intra-abdominal infection (IAI) remain a clinical problem with high mortality rate. Among factors contributed to this mortality, the important one is blood type that never be considered. It was thought to have correlation with a certain type. Thus, a retrospective study as a preliminary study run to find out the evidence. Method. A descriptive analytic with cross sectional design was run. Data of those diagnosed with intraabdominal infection due to abdominal trauma and gastrointestinal infections managed at dr Cipto Mangunkusumo General Hospital was taken from medical record. ABO blood types and microbial culture results in two groups were the focus of a study and were analyzed statistically. Results. In the study, out of 230 subjects, there were 22 subjects (9.6%) with postoperative intra-abdominal infection were observed during January 2014-March 2016. There was a significant correlation between blood transfusion (p <0.001, OR = 0.02) with intraabdominal infection. However, there was no significant correlations found in blood type to the occurrence of intra-abdominal infection. Conclusion. The study unable to show that blood type has a correlation to intra-abdominal infection in those diagnosed with abdominal trauma and gastrointestinal infections.

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Advances in Blood Typing

Cited by 23 publications

References 99 publications

Kai 1 and Kai 2: Characterization of these dog erythrocyte antigens by monoclonal antibodies

Kai 1 and Kai 2: Characterization of these dog erythrocyte antigens by monoclonal antibodies

Relationship between blood type and outcomes following COVID-19 infection

Correlation between Blood Types and Intraabdominal Infection A Preliminary Study

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