“…Taking into account the composition of native bone, in which both organic and inorganic components are found, makes composite materials a logical choice for bone tissue engineering scaffolds [53,66]. Combinatorial approaches in which synthetic materials are combined with biological materials offer both a high degree of tailorability in mechanical properties as well as enhanced instructive properties due to their biological activity [67,68]. These instructive properties can result in enhanced cell attachment, proliferation and differentiation [18,48,[69][70][71][72][73].…”