Advancement in contemporary diagnostic and therapeutic approaches for rheumatoid arthritis

Bioreactor shoot cultures of Rhododendron tomentosum (Ledum palustre) for a large-scale production of bioactive volatile compounds

“…Rheumatoid arthritis, a chronic joint disease, affects about 1% of the world population (Kumar et al 2016). The anti-arthritic treatment is frequently based on plant remedies, which are cheaper, less toxic and more available for patients than synthetic pharmaceuticals, but comparably effective (Kumar et al 2016;Setty and Sigal 2005).…”

“…The anti-arthritic treatment is frequently based on plant remedies, which are cheaper, less toxic and more available for patients than synthetic pharmaceuticals, but comparably effective (Kumar et al 2016;Setty and Sigal 2005). One of the groups of phytocompounds modulating the pro-inflammatory signaling pathways are terpenes, the components of essential oils.…”

UHPLC–MS/MS analysis of sphingosine 1‐phosphate in joint cavity dialysate and hemodialysis solution of adjuvant arthritis rats: Application to geniposide pharmacodynamic study

“…The development of inflammation depends on many physiological and pathological processes. Rheumatoid arthritis (RA), the most common type of inflammatory arthritis, is an autoimmune disease that is characterized by the synovial tissue inflammation and could eventually lead to damage of joint cartilages and bones and even induce disability (de Souza et al, ; Kumar, Karthik, Gayathri, & Sivasudha, ). Research on and development of effective RA drugs and promotion of such drugs around the world is a difficult challenge in the field of traditional Chinese medicine.…”

Microdialysis sampling combined with ultra‐high‐performance liquid chromatography/tandem mass spectrometry for the determination of geniposide in dialysate of joint cavities in adjuvant arthritis rats

“…The most prevalent type of inflammatory arthritis is rheumatoid arthritis (RA), which is an autoimmune disease and occurs in the bone joints due to a damaged immune system. 1,2 It is considered to be the main reason for disability. Geniposide (GE, Figure 1A) is the major iridoid glycoside purified from gardenia fruit which has been used in the production of traditional Chinese medicine (TCM) for many years.…”