Advanced Pathology Techniques for Detecting Emerging Infectious Disease Pathogens

Shieh, Wun‐Ju

doi:10.1007/978-3-319-95111-9_22

Cited by 5 publications

(1 citation statement)

References 83 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our study highlights the critical role of employing both traditional and advanced diagnostic methods, such as PCR and in-vivo confocal microscopy, for accurate pathogen identification, as suggested by Shieh. [10] . This approach is essential for guiding appropriate antimicrobial therapy, thereby improving treatment outcomes.…”

Section: Discussionmentioning

confidence: 99%

Investigating microbial keratitis: A comprehensive clinical and laboratory approach in a tertiary care setting

Jupalli

2019

Int. J. Med. Ophthalmol.

View full text Add to dashboard Cite

Introduction: Microbial keratitis is a serious ocular condition that can lead to significant visual impairment. This study aims to analyze the epidemiology, clinical features, microbiological profiles, and treatment outcomes of microbial keratitis in a tertiary care setting. Material and Methods: A retrospective observational study was conducted at the Ophthalmology Department of Mamata Medical College, Khammam, involving 50 patients with clinically diagnosed microbial keratitis. Data on demographics, clinical presentation, history of contact lens use, associated ocular and systemic conditions, and visual acuity were collected. Microbiological analyses included Gram staining, KOH wet mount, and cultures on blood agar, chocolate agar, and Sabouraud dextrose agar. Treatment efficacy and patient outcomes were also evaluated. Results:The study included 50 patients, with a mean age of 45.3 years and a male predominance (60%). Contact lens use was reported in 30% of cases. The most common presenting symptoms were pain, redness, and blurred vision. Microbiological analysis revealed bacterial growth in 44% on blood agar and 40% on chocolate agar, predominantly with Staphylococcus aureus and Pseudomonas aeruginosa. Fungal elements were identified in 30% of cases on Sabouraud dextrose agar, primarily Candida spp. and Fusarium spp. Treatment outcomes varied based on the causative organism and initial visual acuity. Conclusions: This study highlights the diverse etiology and complex clinical presentation of microbial keratitis in a tertiary care setting. The findings emphasize the importance of comprehensive diagnostic approaches and targeted treatment strategies. Improved understanding of microbial keratitis can lead to better management and outcomes for affected patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Investigating microbial keratitis: A comprehensive clinical and laboratory approach in a tertiary care setting

Jupalli

2019

Int. J. Med. Ophthalmol.

View full text Add to dashboard Cite

show abstract

Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics

Al-Salihi

Alberti

2021

Nat. Prod. Bioprospect.

View full text Add to dashboard Cite

Since the olden times, infectious diseases have largely affected human existence. The newly emerged infections are excessively caused by viruses that are largely associated with mammal reservoirs. The casualties of these emergencies are significantly influenced by the way human beings interact with the reservoirs, especially the animal ones. In our review we will consider the evolutionary and the ecological scales of such infections and their consequences on the public health, with a focus on the pathogenic influenza A virus. The nutraceutical properties of fungal and plant terpene-like molecules will be linked to their ability to lessen the symptoms of viral infections and shed light on their potential use in the development of new drugs. New challenging methods in antiviral discovery will also be discussed in this review. The authors believe that pharmacognosy is the “wave of future pharmaceuticals”, as it can be continually produced and scaled up under eco-friendly requirements. Further diagnostic methods and strategies however are required to standardise those naturally occurring resources.

show abstract

The smartphone biosensors for point-of-care detection of human infectious diseases: Overview and perspectives—A systematic review

Rizi

2022

Current Opinion in Electrochemistry

View full text Add to dashboard Cite

Advanced Pathology Techniques for Detecting Emerging Infectious Disease Pathogens

Cited by 5 publications

References 83 publications

Investigating microbial keratitis: A comprehensive clinical and laboratory approach in a tertiary care setting

Investigating microbial keratitis: A comprehensive clinical and laboratory approach in a tertiary care setting

Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics

The smartphone biosensors for point-of-care detection of human infectious diseases: Overview and perspectives—A systematic review

Contact Info

Product

Resources

About