Adulteration in Herbal Drugs: A Burning Issue

Shaheen, Shabnum; Ramzan, Sehrish; Khan, Farah; Ahmad, Mushtaq

doi:10.1007/978-3-030-28034-5

Cited by 10 publications

(7 citation statements)

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“…Among herbal products exported by India, 10% are Ayurvedic preparations, 30% are crude herbal extracts, and 60% are processed herbal extracts [35]. Some major pharmaceuticals derived from plant materials exported by India include menthol, Mehdi leaves, isabgol, sandalwood oil, cinchona alkaloids, jasmine oil, agarwood oil, and opium alkaloids [36].…”

Section: Indian Herbal Medicine (Ihm)mentioning

confidence: 99%

Traditional Herbal Medicine and Its Clinical Relevance: A Need to Preserve the Past for the Future

Tahir¹,

Hussain²,

Yousuf³

et al. 2022

JBM

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Section: Indian Herbal Medicine (Ihm)mentioning

confidence: 99%

Traditional Herbal Medicine and Its Clinical Relevance: A Need to Preserve the Past for the Future

Tahir¹,

Hussain²,

Yousuf³

et al. 2022

JBM

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“…Factors like unavailability of required species due to extinction, deforestation, high price, resemblance in morphological characteristics, cooccurrence, mislabeling, improper handling and storage, conflict in vernacular names as well scientific names, and unauthorized or fraudulent substitution have a marked contribution to the species adulteration in the herbal products. Adulteration has a very clear and direct impact on the promotion of herbal products [87][88][89][90][91]. It is very important to authenticate the herbal products for their safety and efficacy purposes and of course for the use in the discovery of novel drugs [92].…”

Section: Modern Viewmentioning

confidence: 99%

Calotropis procera (Arka): A Tribal Herb of Utmost Significance

Kumari¹,

Chaudhary²

2021

Int. j. res. appl. sci. biotechnol.

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Nature has gifted humans a vast variety of medicinal plants, which are the rich source of bioactive compounds. Calotropis procera is an important medicinal plant that belongs to the family asclepiadaceae. It is commonly known as madar and milkweed plant in english and arka in hindi. It is mostly found in the tropics of asia and africa. Calotropis procera is a highly valued plant in the folk medication system. Each part of the plant is richly endowed with diverse nature of phytochemical constituents like alkaloids, proteins, vitamins, carbohydrates, saponins, terpenes, and flavonoids, etc. These phytochemicals are significantly associated with various therapeutic and pharmacological properties such as anti-microbial, anti-oxidant, anti-inflammatory, anti-ulcer, antifertility, anti-diarrheal, and spasmolytic. In this review article, the therapeutic and pharmacological value of this important plant has been summarized along with its utilization in the folklore and ayurvedic medicinal system.

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“…Even though AYUSH is one of India's oldest traditional systems of treatment, it has been unable to capitalize on the expanding market's prospects [5]. According to reports, around 8000 herbal species are utilized as ethnomedicine, and ethnic communities have devised 25000 formulations that must be identified, verified, and documented [6]. The pharmaceutical industry has shown less attention for developing herbal medicines due to the complex process of drug development, quality control, security, adequacy, promotion, and administrative guidelines, and medical people are also not interested much in it [7].…”

Section: Introductionmentioning

confidence: 99%

Current Status and Challenges of Herbal Drug Development and Regulatory Aspect: A Global Perspective

Hossain

Gera

Ali

2022

Asian J Pharm Clin Res

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Conventional herbal medication has picked up a gigantic sum of intrigue around the world due to its viability in the treatment of extreme illnesses from the period of antiquated civilizations. Phytomedicines are considered a major health-care supplier around the globe, especially in rustic and farther ranges. A huge segment of individuals depends on or accept home-grown drugs as an essential cure for different afflictions rather than manufactured drugs. Researchers are paying much attention to herbal medicine as compared to synthetic drugs due to their severe side effects, and toxicity with less efficacy and specificity. Despite the significant increase in global interest in the investigation and development of new botanical products, only a few have been approved till now. Natural product medication development has significant technical and monetary hurdles, including a time-consuming formulation process, quality assurance, safety, therapeutic efficacy, promotion, and administrative issues. To meet these challenges, the regulatory agencies EMEA, ICH, AYUSH, DCGI, WHO, and U.S. FDA trying to bring these herbal drugs under the regulatory pipeline under the NDA approval process. Moreover, the process of drug discovery has also been revolutionized with the new advent of technologies such as the successful drug development of a novel therapeutic agent is critically relying on the process which adopts novel approaches and involves the concept of ADMET (i.e., absorption, distribution, metabolism, excretion, and toxicity) in the early stages of drug discovery along with the interaction profiles of herb-herb and herb-synthetic. In the present review, we will address the noteworthy opportunities and issues related to phyto-drug improvement in various developing and developed nations such as Europe, U.S. and India, its commercialization with regulatory guidelines, and recommended potential methods to bring them up into the mainstream of modern medical practices and healthcare.

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Adulteration in Herbal Drugs: A Burning Issue

Cited by 10 publications

References 0 publications

Traditional Herbal Medicine and Its Clinical Relevance: A Need to Preserve the Past for the Future

Traditional Herbal Medicine and Its Clinical Relevance: A Need to Preserve the Past for the Future

Calotropis procera (Arka): A Tribal Herb of Utmost Significance

Current Status and Challenges of Herbal Drug Development and Regulatory Aspect: A Global Perspective

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