Adult rhabdomyoma of the extremity: A case report and review of the literature

Mediastinal rhabdomyoma: case report and review of the literature

“…The most common site is the mucosa of the pharynx, followed by the mucosa of the oral cavity, and the larynx and the branchial musculature of the neck in the distribution of the third and fourth branchial arches. Rare cases have been reported to occur in the extremities [5], esophagus [15], stomach [18], and mediastinum [2,12,17]. To our knowledge, this is the fourth case of adult rhabdomyoma occurring in the mediastinum.…”

“…There have been reported cases with a larger size [5,9] as Histologically, the tumor is composed of well-demarcated lobules that consist of closely packed, large polygonal cells and scant stroma containing thin-walled vascular channels [1,6,8,10,16,17]. The tumor cells have small round centrally or peripherally located nuclei with prominent nucleoli and abundant eosinophilic, granular or peripherally vacuolated cytoplasm [1,7,11,16,17].…”

“…The extracardiac adult rhabdomyoma (EAR) is an extremely uncommon benign neoplasm that usually involves the head and neck region [11]. In the literature, only three cases of EAR have been reported to arise in mediastinum [5,8,10]. Possible origin from the myoid cells of the thymus has been postulated [10].…”

Adult extracardiac rhabdomyoma: Light and immunohistochemical studies of two cases in the parapharyngeal space

“…Both patients were in their sixth decade, and adult rhabdomyomas generally occur in the elderly (median age, 60 years). 2 Although rare in children, these tumors have been described in patients of all ages from 5 weeks to 82 years of age. 5 The tumors are more common in men than in women (up to 6:1).…”

“…5 The tumors are more common in men than in women (up to 6:1). 2 The treatment of rhabdomyoma is complete excision. 6 Recurrence may be as high as 42%, 3 and in one case, three recurrences have been reported within a period of 35 years after primary resection.…”