Adult respiratory distress syndrome: Current concepts

Putterman, Chaim

doi:10.1016/0300-9572(88)90074-3

Cited by 12 publications

(2 citation statements)

References 30 publications

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“…Robbins and Angell (1976) stated that "disseminated intravascular coagulation is the human equivalent of the experimentally produced generalized Shwartzman reaction". DIC is also implicated in adult respiratory distress syndrome (Putterman, 1988), where abnormalities of local coagulation and fibrinolytic systems are thought to occur before the development of the clinical syndrome (Idell, James, Levin, Schwartz, Manchanda, Maunder, Martin, McLarty and Fair, 1989).…”

Section: Discussionmentioning

confidence: 99%

Increased susceptibility of aged rats to haemorrhage and intravascular hypercoagulation following endotoxin administered in a generalized Shwartzman regime

Carthew

Dorman

Edwards

1991

Journal of Comparative Pathology

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Ageing rats are known to have an increased incidence of myocardial fibrosis and dyspnoea caused by pulmonary intravascular coagulation. In order to determine whether endotoxin can be responsible for such responses in ageing rats we have exposed rats of differing ages (2 months, 16 months and 24 months) to single or repeated (two doses 24 h apart; generalized Shwartzman regime) intravenous doses of endotoxin (E. coli 0111 B4). Only the 2-year-old rats reacted adversely. Two doses of endotoxin produced death, with focal myocardial necrosis, haemorrhage and pulmonary and hepatic intravascular coagulation. The increased susceptibility of aged rats to the toxic effects of endotoxin explains some of the changes found in the tissues of old rats. The sporadic nature of both cardiac failure and dyspnoea as a cause of morbidity and mortality in ageing rats may be related to the need for two endotoxin episodes in a period of 24 h to provoke a generalized Shwartzman reaction, an occurrence likely to be relatively uncommon under natural conditions.

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Section: Discussionmentioning

confidence: 99%

Increased susceptibility of aged rats to haemorrhage and intravascular hypercoagulation following endotoxin administered in a generalized Shwartzman regime

Carthew

Dorman

Edwards

1991

Journal of Comparative Pathology

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“…1 in der Neugeborenenperiode; bei den Erwachsenen gibt es erst in jüngster Zeit einige wenige Berichte über eine gegenüber 1967 (Zeitpunkt der Erstbeschreibung des Adult Respiratory Distress Syndrome -ARDS durch Eine kausale Therapie ist nur in Ausnahmefällen verfiigbar. Der klinische Behandlungsansau bleibt bis heute supportiv, die Aufrechterhaltung des Gasaustausches mittels maschineller Ventilation (MV) stellt den Crundpfeiler dar (77,79,80,89).…”

Section: Die Erfolgreiche Behandlung Des Akutenunclassified

Akutes Lungenversagen - Unterstützung des Gasaustausches mittels extrakorporaler oder implantierter Oxygenatoren - Gegenwärtiger Stand und zukünftige Entwicklung

Müller

Kolobow²,

Knoch³

et al. 1992

Anästhesiol Intensivmed Notfallmed Schmerzther

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In acute respiratory failure gas exchange can be supported or even maintained in an "alternative" way to mechanical ventilation using extracorporeal techniques (extracorporeal membrane oxygenation ECMO, extracorporeal CO2-removal ECCO2R), or intravenacaval oxygenators (IVOX). These techniques, which are currently in use in neonatology, pediatrics, and adult intensive care medicine, or techniques at present in clinical evaluation (IVOX), are reviewed with their indications, contraindications, differences, problems, worldwide results, and possible future applications.

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Reactive type II pneumocytes in bronchoalveolar lavage fluid from adult respiratory distress syndrome can be mistaken for cells of adenocarcinoma

Grotte

Stanley

Swanson

et al. 1990

Diagnostic Cytopathology

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A growing body of literature illustrates that bronchoalveolar lavage is a reliable and efficient means of diagnosing primary and secondary malignancies in the lung. Its safety in severely compromised patients often makes it preferable to other biopsy procedures. However, a variety of reparative and degenerative pulmonary disorders may result in cytologic alterations so severe that pneumocytes resemble cells of malignancy. We describe four patients with the adult respiratory distress syndrome from whom lavage fluid showed gland-like groups of malignant-appearing cells morphologically consistent with adenocarcinoma. Transbronchial biopsy sections in one case and lavage fluid electron microscopy in another showed that these pseudomalignant cells were reactive Type II pneumocytes with surface microvilli, cell junctions, and numerous cytoplasmic myelin figures. Careful clinicopathologic correlation is the best way to ensure accurate diagnosis in these cases.

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Adult respiratory distress syndrome: Current concepts

Cited by 12 publications

References 30 publications

Increased susceptibility of aged rats to haemorrhage and intravascular hypercoagulation following endotoxin administered in a generalized Shwartzman regime

Increased susceptibility of aged rats to haemorrhage and intravascular hypercoagulation following endotoxin administered in a generalized Shwartzman regime

Akutes Lungenversagen - Unterstützung des Gasaustausches mittels extrakorporaler oder implantierter Oxygenatoren - Gegenwärtiger Stand und zukünftige Entwicklung

Reactive type II pneumocytes in bronchoalveolar lavage fluid from adult respiratory distress syndrome can be mistaken for cells of adenocarcinoma

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