Adult brain activation during visual learning and memory tasks. An experimental approach to translational neuroscience

Popova, Ferihan; Kovacheva, Antoaneta; Garov, Petar; Sivkov, Stefan; Kandilarova, Sevdalina; Sirakov, Nickolay; Stoeva, Magdalena; Velkova, K

doi:10.1111/jep.12911

Cited by 3 publications

(2 citation statements)

References 19 publications

(37 reference statements)

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“…Greater sample size is probably necessary to find statistical significant differences between the genders when comparing the BOLD-activations. We found similar imaging results in the active brain regions in one of our previous studies applying the same memory paradigm and same volunteers during a period of time when the students were not subjected to intensive learning (24). Therefore, further research and statistical analysis is indispensable for evaluation of the specific differences in cortical activation areas between both conditions in order to contribute to the disclosure of the way brain works in health and disease.…”

Section: Discussionsupporting

confidence: 78%

An fMRI Study of Adult Brain Cortical Activation Following Intensive Learning

et al. 2020

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Functional imaging techniques, fMRI in particular, has given the possibility to investigate non-invasively the cognitive processes in healthy populations and different disorders concerning neuro-psychiatry, thus unfolding the concepts guiding diagnosis and patient management. Different brain structures seem to support different types of cognitive functions in particular learning and memory thus the neurobiological explanation of the retrieval of information is associated with knowledge of brain plasticity, memory circuits, synaptic neurotransmission and the modulation of glial cells. Consistent with fMRI investigations of memory systems we tested the dependability of a memory paradigm using heterogeneous memory stimuli in order to find the neurobiological basis that correlates with memory task performance. Our study resulted with statistical significant differences in brain activations across the block design contrasts in both occipital and temporal regions in 29 mentally healthy students during a memory paradigm performance after intensive learning. As functional magnetic resonance imaging has become an important and reliable tool for investigation of brain anatomy and its function in health and disease, it becomes clear that further research of neurobiological basis of cognitive and memory domains can clarify different diagnostic prototypes and thus explain the human brain impairments in neuropsychological patients, since these are characterized by various cognitive dysfunctions.

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Section: Discussionsupporting

confidence: 78%

An fMRI Study of Adult Brain Cortical Activation Following Intensive Learning

et al. 2020

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“…Is it the method of clinical evaluation or the in vivo neuroimaging technique? The paper contributed by Popova and colleagues on adult brain activation during visual learning and memory tasks describes an experimental approach to translational neuroscience in the context of such questions and provides many clues for the direction of ongoing research.…”

Section: Translating the Findings Of Neuroscience Into Clinical Medicmentioning

confidence: 99%

Editorial introduction: The implications of translational neuroscience for clinical practice and its evaluation

Miles¹

2018

Evaluation Clinical Practice

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Are there sex differences in brain activity during long-term memory? A systematic review and fMRI activation likelihood estimation meta-analysis

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Slotnick

2020

Cognitive Neuroscience

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Adult brain activation during visual learning and memory tasks. An experimental approach to translational neuroscience

Abstract: The results highlighted several detailed distinctions between the genders and potential future directions in brain activation studies as part of the multidisciplinary approach in translational neuroscience.

Cited by 3 publications

References 19 publications

An fMRI Study of Adult Brain Cortical Activation Following Intensive Learning

An fMRI Study of Adult Brain Cortical Activation Following Intensive Learning

Editorial introduction: The implications of translational neuroscience for clinical practice and its evaluation

Are there sex differences in brain activity during long-term memory? A systematic review and fMRI activation likelihood estimation meta-analysis

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