Adsorptive stripping voltammetry applied to drug analysis: A powerful tool

Vire, J. C.; Kauffmann, J.M.; Patriarche, Gaston

doi:10.1016/0731-7085(89)80138-4

Cited by 33 publications

(15 citation statements)

References 66 publications

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“…Unfortunately, many analytes (e.g. organic molecules) cannot be accumulated at the electrode surface by a reversible faradaic process and some approaches have been developed, such as adsorptive stripping voltammetry [9][10][11][12], electrochemical generation of sparingly-soluble complexes prior to stripping analysis [13], or extractive stripping voltammetry [14]. Insertive stripping voltammetry has been also proposed for the detection of non-redox ions [15].…”

Section: Introductionmentioning

confidence: 99%

Signal amplification by electro-oligomerisation for improved isoproturon detection

Nasir

Gamero‐Quijano

Despas

et al. 2020

Talanta

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A novel concept is introduced for signal amplification in electrochemical sensing: the electrooligomerisation stripping voltammetry, which has been applied here to the improved detection of the isoproturon herbicide in spring waters as a proof-of-principle. It involves a potentiostatic accumulation step onto a glassy carbon electrode (at +1.5 V vs Ag/AgCl reference electrode for 300 s) leading to the formation of an oligomeric film, which is then detected by cathodic stripping square wave voltammetry (SWV). The presence and composition of the film are confirmed by confocal Raman spectroscopy. Its characterisation by cyclic voltammetry demonstrates the reversible nature of the electrodeposited material, confirming its interest for sensitive detection by SWV. Adding a mesoporous silica membrane with vertically oriented nanochannels further enhances the sensitivity of the sensor, exhibiting a linear response in the 10-100 µM concentration range. This effect was even more interesting for real media analysis thanks to the permselective properties of such nanoporous coating in rejecting interferences and/or surface fouling agents. The method should be applicable to other analytes that are usually not detectable by conventional accumulation/stripping voltammetry.

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Section: Introductionmentioning

confidence: 99%

Signal amplification by electro-oligomerisation for improved isoproturon detection

Nasir

Gamero‐Quijano

Despas

et al. 2020

Talanta

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“…Consequently, for a wide range of surface-active organic and inorganic species, which cannot be preconcentrated electroanalytically, the adsorption approach allows these analytes to be interfacially accumulated on the electrode and hence analysed. There have been many reviews devoted to emphasize and illustrate the wide spectrum and scope of adsorptive stripping vol-tammetric applications and potentialities in the analysis of metal ions [6,7] organic analytes [8,9] and pharma-ceutical drugs and biomedical compounds, such as, the anti-Inflammatory drug Lornoxicam, the antidepressant drug sulpiride and Josamycin, a Macrolide Antibiotic [10][11][12][13][14]. Timolol was the first beta (β) blocker to be used as an anti-glaucoma agent and to date remains as the standard because none of the newer β blockers were found to be more effective.…”

Section: Introductionmentioning

confidence: 99%

Stripping Voltammetric Determination of Timolol Drug in Pharmaceuticals and Biological Fluids

Alghamdi¹

2011

AJAC

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A sensitive and reliable stripping voltammetric method was developed to determine timolol drug. This method is based on the adsorptive accumulation of the drug at a hanging mercury drop electrode (HMDE) and then a negative sweep was initiated, which yield a well defined cathodic peak at –850 mV versus (Ag/AgCl) silver reference electrode. To achieve high sensitivity, various experimental and instrumental variables were investigated such as supporting electrolyte, pH, accumulation time and potential, scan rate, frequency, pulse amplitude, convection rate and working electrode area. The monitored adsorptive current was directly proportional to the concentration of timolol and it shows a linear response in the range from 1 × 10–7 to 1.5 × 10–6 mol●l–1 of this drug (correlation coefficient = 0.998) and the detection limit (S/N = 3) is 1.26 × 10–9 mol●l–1 at an accumulation time of 30 sec. The developed adsorptive stripping voltammetry (AdSV) procedure shows a good reproducibility, the relative standard deviation RSD% (n = 8) at a concentration level of 1 × 10–6 mol●l–1 of timolol was 0.13%, whereas the method accuracy was indicated via the mean recovery of 110% ± 1.414%. Possible interferences by several substances usually present in the pharmaceutical formulations have been also evaluated. The applicability of this approach was illustrated by the determination of the drug in pharmaceutical preparation and biological fluids such as serum and urine

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“…electroanalytical determinations [1][2][3][4]. The applicability of the adsorptive accumulation procedure in the determination of pharmaceutical drugs in biological fluids and drug dosage forms have been reviewed elsewhere [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Square-wave adsorptive stripping voltammetric determination of danazol in capsules

Alghamdi

Belal

Al-Omar

2006

Journal of Pharmaceutical and Biomedical Analysis

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Adsorptive stripping voltammetry applied to drug analysis: A powerful tool

Cited by 33 publications

References 66 publications

Signal amplification by electro-oligomerisation for improved isoproturon detection

Signal amplification by electro-oligomerisation for improved isoproturon detection

Stripping Voltammetric Determination of Timolol Drug in Pharmaceuticals and Biological Fluids

Square-wave adsorptive stripping voltammetric determination of danazol in capsules

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