Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate Ligand

Abstract

Due to the fast, emerging development of antibiotic-resistant bacteria, the need for novel, efficient routes to battle these pathogens is crucial; in this scenario, metal-organic frameworks (MOFs) are promising materials for combating them effectively. Herein, a novel Cu-MOF—namely 1—that displays the formula [Cu3L2(DMF)2]n (DMF = N,N-dimethylformamide) is described, synthesized by the combination of copper(II) and 3,4-dihydroxybenzoic acid (H3L)—both having well-known antibacterial properties. The resulting three-dimensional structure motivated us to study the antibacterial activity, adsorptive capacity and processability of the MOF in the form of pellets and membranes as a proof-of-concept to evaluate its future application in devices.

Mechanochemical Synthesis and Three-Dimensional Electron Diffraction Structure Solution of a Novel Cu-Based Protocatechuate Metal–Organic Framework

“…The crystalline phase was not modified by the presence of different liquid media except in the presence of DMF, in which the resulting PXRD pattern matches with the [Cu 3 (PC) 2 (DMF) 2 ] n phase ( Figure S3 ). 35 …”

“…Remarkably, the PC-MOF presents a 3D lattice in which water molecules are trapped and are not coordinated with metal nodes. This totally differs from a similar structure synthesized via the solvothermal method using N , N -dimethylformamide as the solvent . The PC-MOF structure is flexible and stable in several organic solvents or aqueous solutions at different pH.…”

“…This totally differs from a similar structure synthesized via the solvothermal method using N , N -dimethylformamide as the solvent. 35 The PC-MOF structure is flexible and stable in several organic solvents or aqueous solutions at different pH. The MOF was also extensively characterized.…”

“…The possibility of obtaining a PC-MOF has already been demonstrated. However, the only explored synthesis route is a classical solvothermal using N , N -dimethylformamide (DMF) as the solvent, which results to be coordinated to the MOF framework in its structure . Herein, we demonstrate the possibility of substituting this synthesis route with a green mechanochemical approach that leads to a solvent-free PC-MOF with only water in its pores.…”

“…However, the only explored synthesis route is a classical solvothermal using N , N -dimethylformamide (DMF) as the solvent, which results to be coordinated to the MOF framework in its structure. 35 Herein, we demonstrate the possibility of substituting this synthesis route with a green mechanochemical approach that leads to a solvent-free PC-MOF with only water in its pores. In addition, complete structural and thermal characterization has been carried out with a specific focus on the dehydration profiles and consequent reorganization of the structure.…”