Adolescent Girls and Pelvic Inflammatory Disease

Benaim, J; Pulaski, Mary; Coupey, Susan M.

doi:10.1001/archpedi.152.5.449

Cited by 13 publications

(3 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Prior surveys of practitioners related to the guidelines demonstrated that less than half of primary care physicians knew about or followed the recommendations for PID and found poor compliance with disposition criteria for adolescents diagnosed with PID. 19 Hessol et al, 20 in a survey of primary care physicians, found only 44% reported following the CDC guidelines and that 52% were unaware of the guidelines or they did not follow them. One retrospective study looking at patients with documented positive cultures for gonorrhea or chlamydia found only 53% of patients were correctly diagnosed and treated in the ED.…”

Section: Discussionmentioning

confidence: 99%

Compliance with the Centers for Disease Control and Prevention Recommendations for the Diagnosis and Treatment of Sexually Transmitted Diseases

Kane

Degutis

Sayward

et al. 2004

Academic Emergency Medicine

View full text Add to dashboard Cite

Little is known about gaps in quality and the extent to which clinical standards are used in emergency department (ED) practice. Objectives: To determine whether ED practitioners comply with the Centers for Disease Control and Prevention (CDC) recommendations for diagnosing and treating sexually transmitted diseases (STDs). Methods: A retrospective chart review of ED visits was conducted at an urban teaching hospital. Using ICD-9 codes, urethritis, cervicitis, pelvic inflammatory disease (PID), gonorrhea, and chlamydia cases seen from May 1, 2000, to February 28, 2001, were identified. Documentation of components of the history, physical examination, diagnostic testing, prescribed antibiotics, and discharge instructions necessary to comply with the CDC guidelines were abstracted. This set of comprehensive criteria was compared with a less stringent subset of selected criteria. Results: Two hundred forty-six patient visits were identified, and 203 (83%) were included. Forty-eight men and 155 women were included: 48 (24%) with urethritis, 34 (17%) with cervicitis, and 121 (60%) with PID. For urethritis, cervicitis, and PID, respectively, there was documentation of compliance with indicators related to the following: history 73%, 15%, and 14%; physical examinations 63%, 15%, and 22%; diagnostic testing 79%, 71%, and 71%; antibiotic use 33%, 32%, and 32%; and safe sex instructions 50%, 18%, and 15% of the time. Men were more likely to receive safe sex instructions (p # 0.01). Total (100%) compliance in all five domains occurred 8% of the time for urethritis, 3% for cervicitis, and never for PID. The rates of 100% compliance were not significantly different when a subset of selected criteria was used. Conclusions: Deficits in adherence to recommended guidelines for the diagnosis and treatment of STDs exist in ED practice.

show abstract

Section: Discussionmentioning

confidence: 99%

Compliance with the Centers for Disease Control and Prevention Recommendations for the Diagnosis and Treatment of Sexually Transmitted Diseases

Kane

Degutis

Sayward

et al. 2004

Academic Emergency Medicine

View full text Add to dashboard Cite

show abstract

“…In modern industrialized countries, the annual incidence of PID in women aged 15–39 years seems to be 10–13 per 1,000 women, with peak incidence of about 20 per 1,000 in the age-group 20–24 years. 11 , 12…”

Section: Introductionmentioning

confidence: 99%

“…In modern industrialized countries, the annual incidence of PID in women aged 15-39 years seems to be 10-13 per 1,000 women, with peak incidence of about 20 per 1,000 in the agegroup 20-24 years. 11,12 Medicinal herbs and formulations thereof have been used for treating inflammatory diseases for centuries. For instance, arthritis, oralinflammation, eyeinflammation, postsurgical inflammation, edema, and rheumatism are frequently treated in Ayurvedic and Unani medicine.…”

Section: Introductionmentioning

confidence: 99%

<p>Active <em>Cousinia thomsonii</em> Extracts Modulate Expression of Crucial Proinflammatory Mediators/Cytokines and NFκB Cascade in Lipopolysaccharide-Induced Albino Wistar Rat Model</p>

Dar

Khan

Amin

et al. 2020

JIR

View full text Add to dashboard Cite

Introduction Chronic inflammation is implicated in a multitude of diseases, including arthritis, neurodegeneration, autoimmune myositis, type 2 diabetes, rheumatic disorders, spondylitis, and cancer. Therefore, strategies to explore potent anti-inflammatory regimens are pivotal from a human-health perspective. Medicinal plants represent a vast unexplored treasure trove of therapeutically active constituents with diverse pharmacological activities, including anti-inflammatory properties. Herein, we evaluated Cousinia thomsonii , an edible medicinal herb, for its anti-inflammatory/immunomodulatory properties. Methods Soxhlet extraction was used to obtain different solvent extracts (hexane, ethyl acetate, ethanol, methanol, and aqueous extract) in increasing order of polarity. In vitro anti-inflammatory assays were performed to investigate the effects of extracts on protein denaturation, proteinase activity, nitric oxide surge, and erythrocyte-membrane stabilization. The most effective extracts, ie, ethyl acetate (CTEA) and ethanol (CTE) extracts (150–200 g) were selected for further in vivo analysis using albino Wistar rats. Wistar rats received varying concentrations of CTEA and CTE (25, 50, and 100 mg/kg) for 3 weeks, followed by a single subplantar injection of lipopolysaccharide. Dexamethasone served as positive control. Blood was obtained from the retro-orbital plexus and serum separated for estimation of proinflammatory cytokines (IL6, IL1β, IFNγ and TNFα). Western blotting was performed to study expression patterns of crucial proteins implicated in the NFκB pathway, ie, NFκB p65, NFκB1 p50, and NFκB2 p52. Histopathological examination was done and gas chromatography–mass spectrometry (GC-MS) carried out to reveal the identity of compounds responsible for ameliorating effects of C. thomsonii. Results Among five tested extracts, CTEA and CTE showed marked inhibition of protein denaturation, proteinase activity, nitric oxide surge and erythrocyte-membrane hemolysis at 600 μg/mL ( P <0.001). Both these extracts showed no toxic effects up to a dose of 2,500 mg/kg. Extracts exhibited concentration-dependent reductions in expression of IL6, IL1β, IFNγ, TNFα, NFκB-p65, NFκB1, and NFκB2 ( P <0.05). Healing effects of extracts were evident from histopathological investigation. GC-MS analysis revealed the presence of important anti-inflammatory compounds, notably stigmast-5-en-3-ol, oleate, dotriacontane, ascorbic acid, n -hexadecanoic acid, and α-tocopherol, in C. thomsonii. Conclusion C. thomsonii possesses significant anti-inflammatory/immunomodulatory potential by virtue of modifying levels of proinflammatory cytokines/markers and NFκB proteins.

show abstract

Use of an Institutional Intervention to Improve Quality of Care for Adolescents Treated in Pediatric Ambulatory Settings for Pelvic Inflammatory Disease

Trent

Judy

Ellen

et al. 2006

Journal of Adolescent Health

View full text Add to dashboard Cite

Adolescent Girls and Pelvic Inflammatory Disease

Cited by 13 publications

References 17 publications

Compliance with the Centers for Disease Control and Prevention Recommendations for the Diagnosis and Treatment of Sexually Transmitted Diseases

Compliance with the Centers for Disease Control and Prevention Recommendations for the Diagnosis and Treatment of Sexually Transmitted Diseases

<p>Active <em>Cousinia thomsonii</em> Extracts Modulate Expression of Crucial Proinflammatory Mediators/Cytokines and NFκB Cascade in Lipopolysaccharide-Induced Albino Wistar Rat Model</p>

Use of an Institutional Intervention to Improve Quality of Care for Adolescents Treated in Pediatric Ambulatory Settings for Pelvic Inflammatory Disease

Contact Info

Product

Resources

About