Admissions Rate and Timing of Revascularization in the United States in Patients With Non-ST-Elevation Myocardial Infarction

Case, Brian C.; Yerasi, Charan; Wang, Yanying; Forrestal, Brian J.; Hahm, Joshua; Dolman, Sarahfaye; Weintraub, William S.; Waksman, Ron

doi:10.1016/j.amjcard.2020.08.010

Cited by 18 publications

(14 citation statements)

References 19 publications

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“…The proportion of left main coronary artery and left circumflex coronary artery as a culprit lesion was significantly higher in NSTEMI patients than in STEMI patients in this study, suggesting that NSETMI population included high-risk subset of patients who presented “non-ST elevation” electrocardiographic findings, but had a “STEMI like” hemodynamic consequence during evolving myocardial infarction. The recent study reported the favorable clinical outcome of shorter door to balloon time even in NSTEMI population, suggesting the importance of appropriate risk stratification and timely reperfusion therapy in NSTEMI population [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction

et al. 2021

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Background The detailed causes of death in non–ST-segment–elevation myocardial infarction (NSTEMI) have not been adequately evaluated compared to those in ST-segment elevation myocardial infarction (STEMI). Methods The study population was 6,228 AMI patients who underwent percutaneous coronary intervention (STEMI: 4,625 patients and NSTEMI: 1,603 patients). The primary outcome was all-cause death. Results Within 6 months after AMI, the adjusted mortality risk was not significantly different between NSTEMI patients and STEMI patients (HR: 0.83, 95%CI: 0.67–1.03, P = 0.09). Regarding the causes of death within 6 months after AMI, mechanical complications more frequently occurred in STEMI patients than in NSTEMI patients, while proportions of post resuscitation status on arrival and heart failure were higher in in NSTEMI patients than in STEMI patients. Beyond 6 months after AMI, the adjusted mortality risk of NSTEMI relative to STEMI was not significantly different. (HR: 1.04, 95%CI: 0.90–1.20, P = 0.59). Regarding causes of death beyond 6 months after AMI, almost half of deaths were cardiovascular causes in both groups, and breakdown of causes of death was similar between NSTEMI and STEMI. Conclusion The mortality risk within and beyond 6 months after AMI were not significantly different between STEMI patients and NSTEMI patients after adjusting confounders. Deaths due to post resuscitation status and heart failure were more frequent in NSTEMI within 6 months after AMI.

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Section: Discussionmentioning

confidence: 99%

Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction

et al. 2021

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“… 1 Among patients suffering an AMI, non–ST‐segment–elevation MI (NSTEMI) is approximately twice as common as ST‐segment–elevation myocardial infarction (STEMI). 2 The efficacy of immediate reperfusion in the setting of STEMI is well established, consistent with the pathophysiology of atherosclerotic plaque rupture/erosion and thrombosis. 3 In patients with NSTEMI, the efficacy of an invasive strategy with revascularization in appropriate patients is also well established.…”

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confidence: 80%

“…Of these hospitalizations, 50.3% involved diagnostic angiography, with 34.1% revascularized. 2 Of revascularized patients, 77.6% underwent percutaneous coronary intervention and 22.4% underwent coronary artery bypass grafting. Although percutaneous coronary intervention was frequently performed on the day of admission, the majority occurred over the next several days.…”

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confidence: 99%

Non–ST‐Segment–Elevation Myocardial Infarction: When Is Rapid Revascularization Critical?

Case

Weintraub

2021

JAHA

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“… 29 Although symptom-to-revascularization time is less frequently studied in patients with NSTEMI/UA, studies have demonstrated worse outcomes in high-risk patients when revascularization is delayed. 30 …”

Section: Introductionmentioning

confidence: 99%

Impact of COVID-19 on Acute Myocardial Infarction Care

et al. 2022

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Admissions Rate and Timing of Revascularization in the United States in Patients With Non-ST-Elevation Myocardial Infarction

Cited by 18 publications

References 19 publications

Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction

Differences in mortality and causes of death between STEMI and NSTEMI in the early and late phases after acute myocardial infarction

Non–ST‐Segment–Elevation Myocardial Infarction: When Is Rapid Revascularization Critical?

Impact of COVID-19 on Acute Myocardial Infarction Care

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