Admission hyperglycemia and all-cause mortality in diabetic and non-diabetic patients with acute myocardial infarction: a tertiary center analysis

Ferreira, João; Baptista, Rui; Monteiro, Sílvia; Gonçalves, Francisco; Monteiro, Pedro; Gonçalves, Lino

doi:10.1007/s11739-021-02693-0

Cited by 25 publications

(32 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Stress hyperglycemia has been proven to be a strong predictor of a poor prognosis in ACS patients, particularly patients with AMI (12,14,15,(30)(31)(32). On the one hand, stress hyperglycemia reflects the seriousness of an emergency and poor glucose control to some extent.…”

Section: Discussionmentioning

confidence: 99%

“…A number of previous studies have shown that acute hyperglycemia at admission is independently associated with a poor early and late prognosis in acute coronary syndrome (ACS) patients, especially those diagnosed with acute myocardial infection (AMI) (12)(13)(14)(15). However, the admission blood glucose (ABG) level cannot entirely reflect the acute hyperglycemic state, which could also be affected by the chronic glucose level.…”

mentioning

confidence: 99%

See 1 more Smart Citation

The Impact of the Stress Hyperglycemia Ratio on Short-term and Long-term Poor Prognosis in Patients With Acute Coronary Syndrome: Insight From a Large Cohort Study in Asia

Yang

Zheng

et al. 2022

Diabetes Care

View full text Add to dashboard Cite

OBJECTIVE In recent years, some studies have indicated that a novel marker described as the stress hyperglycemia ratio (SHR) can reflect true acute hyperglycemic status and is associated with the short-term poor prognosis in patients with acute myocardial infarction. In the current study we evaluated the association of SHR with adverse cardiovascular events among patients with acute coronary syndrome (ACS). RESEARCH DESIGN AND METHODS We consecutively enrolled 5,562 ACS patients who underwent drug-eluting stent (DES) implantation. All subjects were divided into five groups according to SHR, which was determined by the following formula: ABG / [(28.7 × HbA1c %) − 46.7], where ABG is admission blood glucose level. The primary end point was major adverse cardiovascular and cerebrovascular events (MACCE) at the 2-year follow-up, and the secondary end point included major adverse cardiovascular events (MACE) at 2-year follow-up, cardiac death, and nonfatal myocardial infarction (MI) at 2-year follow-up and in-hospital cardiac death and nonfatal MI. RESULTS A total of 643 MACCE were recorded during a median follow-up of 28.3 months. Kaplan-Meier survival analysis showed the lowest MACCE incidence in quintile 3 (P < 0.001). Moreover, the outcomes of restricted cubic spline analysis suggested that there was a U-shaped or J-shaped association between the SHR and early and late cardiovascular outcomes even after adjustment for other confounding factors. CONCLUSIONS There were U-shaped associations of SHR with MACCE rate and MACE rate at 2-year follow-ups and J-shaped associations of SHR with in-hospital cardiac death and MI and that at 2-year follow-up in ACS patients who underwent DES implantation, and the inflection point of SHR for poor prognosis was 0.78.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

The Impact of the Stress Hyperglycemia Ratio on Short-term and Long-term Poor Prognosis in Patients With Acute Coronary Syndrome: Insight From a Large Cohort Study in Asia

Yang

Zheng

et al. 2022

Diabetes Care

View full text Add to dashboard Cite

show abstract

“…Blood glucose level on admission is an important prognostic factor for patients with AMI. 7 , 8 Studies have shown that LGI may be a marker of systemic inflammatory response and a good predictor of adverse outcomes in various situations in critical care medicine, such as MI and stroke. 6 , 9–13…”

Section: Introductionmentioning

confidence: 99%

Prognostic Value of the Leuko-Glycemic Index in Acute Myocardial Infarction Patients with or without Diabetes

Qi¹,

Liu²,

Cheng³

et al. 2022

DMSO

View full text Add to dashboard Cite

“…Many observational studies have documented that hyperglycemia frequently occurs among patients hospitalized with the acute coronary syndrome (ACS) and without diabetes mellitus ( Capes et al, 2000 ; Kosiborod et al, 2005 ; Ferreira et al, 2021 ). Epidemiological studies showed that 25–50% of ACS patients had elevated blood glucose levels at admission ( Deedwania et al, 2008 ).…”

mentioning

confidence: 99%

“…To date, despite numerous studies regarding hyperglycemia during cardiovascular events have been published, there’s not a clear definition for AH in the setting of ACS. Most early studies defined hyperglycemia by the first available glucose value or admission blood glucose levels ( Capes et al, 2000 ; Kosiborod et al, 2005 ; Deedwania et al, 2008 ; Ferreira et al, 2021 ). Nevertheless, the cutpoint of AH used to define hyperglycemia in patients with ACS was different from study to study.…”

mentioning

confidence: 99%

Editorial: Hyperglycemia and Coronary Artery Diseases: Physio-Pathological Findings and Therapeutic Implications

2022

View full text Add to dashboard Cite

Admission hyperglycemia and all-cause mortality in diabetic and non-diabetic patients with acute myocardial infarction: a tertiary center analysis

Cited by 25 publications

References 38 publications

The Impact of the Stress Hyperglycemia Ratio on Short-term and Long-term Poor Prognosis in Patients With Acute Coronary Syndrome: Insight From a Large Cohort Study in Asia

The Impact of the Stress Hyperglycemia Ratio on Short-term and Long-term Poor Prognosis in Patients With Acute Coronary Syndrome: Insight From a Large Cohort Study in Asia

Prognostic Value of the Leuko-Glycemic Index in Acute Myocardial Infarction Patients with or without Diabetes

Editorial: Hyperglycemia and Coronary Artery Diseases: Physio-Pathological Findings and Therapeutic Implications

Contact Info

Product

Resources

About