Admission C-reactive protein, WBC count, glucose, and body temperature in severe odontogenic infections: a retrospective study using severity scores

Evolution of the treatment of severe odontogenic infections over 50 years: A comprehensive review

“…Some laboratory tests, such as C-reactive protein and white blood cell (WBC) counts, have been used to assess infection severity at patient admission, as a measure of treatment success for severe odontogenic infections. 4 , 10 , 19 , 20 , 21 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 Although few published articles have addressed this topic, the theme is increasingly being discussed. Four articles on tomographic examinations for diagnosis and therapy monitoring were evaluated.…”

“…WBC count and serum glucose are useful prognostic indicators of infection severity and must be determined upon admission for odontogenic infections. 10 , 11 , 12 A WBC count greater than 11,000/ml may be considered to indicate high risk 11 and is suitable for predicting infections in multiple sites. 13 The neutrophil/lymphocyte ratio is also valuable as a prognostic marker: a ratio greater than 5.19 is indicative of higher antibiotic doses and longer hospitalization.…”

“…Body temperature and mean platelet volume are not considered adequate prognostic indicators. 10 , 14 Whereas one article has stated that serum C-reactive protein (CRP) is not a good prognostic indicator, 10 several others have indicated that serum CRP is a good predictor of length of hospital stay and can be used to determine the severity of infection. 4 , 12 , 13 , 15 , 16 , 17 , 18 , 19 , 20 , 21 Therefore, CRP may be considered a useful tool for monitoring the effectiveness of applied therapy and decision-making regarding surgical management.…”

Is patient‐reported symptom onset associated with odontogenic infection severity?

“…This finding is similar to previous reports. [15][16][17] Also, patients with higher OISSs had a significantly longer hospital duration. This finding is expected because infections of higher severity require more surgical dissection and postoperative care.…”

Complications of Severe Odontogenic Infections: A Review

“…This is especially true for patients with poorly controlled diabetes, as the susceptibility to infection increases drastically [ 16 , 17 ]. In a study investigating severe odontogenic infections, Hammad et al found a significantly higher blood glucose level at admission in patients with odontogenic infection severity scores greater than or equal to five [ 18 ]. Other reported factors that play a role in the development of severe odontogenic infections include obesity, drug abuse, tobacco abuse, alcohol abuse, and malnutrition [ 19 , 20 , 21 ].…”